| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | D-Penicillamine |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually3-5days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram，Alibaba Assurance Order |
| Supply Ability: | 5000kg/Month |
| CAS: | 52-67-5 | Mf: | C5H11NO2S |
|---|---|---|---|
| MW: | 149.21 | Specification: | 98% |
| EINECS: | 200-148-8 | Appearance: | White Crystalline Powder |
| Sample: | Available | ||
| High Light: | CAS 52-67-5,98% D-Penicillamine Powder,Antidotes D-Penicillamine Powder |
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CAS 52-67-5 Pharmaceutical Grade 98% D-Penicillamine Powder Antidotes
|
Product name |
D-Penicillamine |
|
Appearance |
White crystalline powder |
|
CAS |
52-67-5 |
|
MF |
C5H11NO2S |
|
Purity |
99% |
|
Storage |
Keep in cool dry place. |
The Introductction of D-Penicillamine
D-Penicillamine is a colorless powdery crystal with a faint odor of aminosulfur, soluble in water, slightly soluble in ethanol, and practically insoluble in ethe*, chloroform, carbon tetrachloride, aliphatic or aromatic hydrocarbons.
D-Penicillamine is one of the drugs to increase urinary copper excretion, and it is also the world's first oral drug for the treatment of WD, which has been clinically applied since 1956, and it is still the first-line drug for the treatment of this disease, and it is the drug of choice in developing countries. D-Penicillamine can chelate copper through sulfhydryl group and promote the excretion of copper from urine; it can also induce the production of hepatic cell metallothionein, which can reduce the hepatotoxicity of copper after combining with copper. The response and tolerance of D-penicillamine are highly variable among patients, and individualized treatment regimens should be developed according to different patients.
The Application & Function of D-Penicillamine
D-Penicillamine is mainly used for copper poisoning, also effective for aluminum, mercury and zinc, etc., the exclusion of lead is not as good as calcium EDTA, and the exclusion of mercury is not as good as BAL.
D-Penicillamine is used for rheumatoid arthritis, chronic active hepatitis, scleroderma, dry mouth and eyes, arthritis syndrome and other autoimmune diseases, can be seen to have a significant therapeutic effect. Rheumatoid arthritis, can reduce joint pain, swelling and oozing, morning stiffness, blood Shen rate and other clinical symptoms significantly improved, generally need a few weeks before the effect can be seen, premature discontinuation of the drug is easy to relapse.
D-Penicillamine can make chronic active hepatitis patients aminotransferase decreased or normalized. Used in the treatment of scleroderma, can make the skin collagen cross-linkage decrease, tension increase.
Other Name of D-Penicillamine
H-D-Pen-OH
Penicilllamine
D-Penicillamine
D(-)-Penicillamine
D-(-)-Penicillamine
N,N-dimethylcysteine
3,3-Dimethyl-D(-)-cysteine
D-minus-penicillamine free base
3,3-Dimethyl-D-cysteine~3-Mercapto-D-valine
The COA of D-Penicillamine
| ITEMS OF ANALYSIS | SPECIFICATIONS | RESULT |
| Appearance | White crystalline powder | Complies |
| Assay(HPLC) | 98.0%～101.0%(on dried basis) | 99.6% |
| Identification | HPLC | Complies |
| IR | Complies | |
| Solubility | Complies | Complies |
| Loss on drying | ≤ 0.5% | 0.32% |
| Residue on ignition | ≤ 0.1% | 0.06% |
| Heavy Metals | ≤ 20ppm | <20ppm |
| Conclusion | Complies With USP43 standard | |
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