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CAS 6902-77-8 Pharmaceutical Grade 98% Genipin Powder Natural Bio-Crosslinking Agents

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Genipin
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 6902-77-8 Mf: C11H14O5
MW: 226.23 Specification: 98%
EINECS: 300-006-4 Appearance: White Crystalline Powder
Sample: Available
High Light:

98% Genipin Powder


Pharmaceutical Grade Genipin Powder


API Pharmaceutical 6902-77-8

Product Description

CAS 6902-77-8 Pharmaceutical Grade 98% Genipin Powder Natural Bio-Crosslinking Agents

CAS 6902-77-8 Pharmaceutical Grade 98% Genipin Powder Natural Bio-Crosslinking Agents 0

Product name



White crystalline powder








Keep in cool dry place.


The Introductction of Genipin

Genipin is white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from gardenia fruit.


Genipin is a natural cross-linking agent extracted from the fruit of Gardenia jasminoides. It can prevent lipid peroxidation and nitric oxide production. Genipin protects hippocampal neurons from Alzheimer′s disease β-amyloid toxicity. Has anti-inflammatory and anti-angiogenic effects. Involved in drug delivery system.


Genipin is generally prepared by extracting genipin glycosides from gardenia, then hydrolyzing them with β-glucosidase, followed by extraction with ethe*, vacuum concentration, and recrystallization, or it can be prepared by microbial transformation.


The Application & Function of Genipin

Genipin has a variety of biological activities including protein modulation, anti-tumor, anti-inflammatory, immunosuppressive, anti-thrombotic and hippocampal neuron protection.Genipin is also used in type 2 diabetes research.


Genipin is an anticholinergic inhibitor of gastric function, anticancer and hepatoprotective.


Genipin increases mitochondrial membrane potential, increased ATP levels, closed KATP channels, and stimulated insulin secretion in pancreatic islet cells. Genipin causes suppression of insulin signal transduction through hyperactivation of c-Jun N-terminal kinase (JNK) and subsequent serine phosphorylation of insulin receptor substrate-1 (IRS-1), thus impairing insulin-stimulated glucose uptake in 3T3-L1 adipocytes. Genipin activates IRS-1, PI3-K, and downstream signaling pathway and increases concentrations of calcium, resulting in glucose transporter 4 (GLUT4) translocation and glucose uptake increase in C2C12 myotubes. Cytochrome c content increases significantly in the cytosol of Genipin-treated FaO cells. Activation of caspase-3 and caspase-7 is ultimately responsible for Genipin-induced apoptotic process in hepatoma cells. ROS level notably increases in Hep3B cells treated with 200 μM Genipin.


Other Name of Genipin






The COA of Genipin



Appearance White crystalline powder Complies
Assay(HPLC) 98.0%~101.0%(on dried basis) 99.8%
Identification HPLC Complies
IR Complies
Solubility Complies Complies
Loss on drying ≤ 0.5% 0.18%
Residue on ignition ≤ 0.1% 0.03%
Heavy Metals ≤ 20ppm <20ppm
Conclusion Complies With USP43 standard


Contact Details
Beryl Jia

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