| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO9001 |
| Model Number: | Scopolamine Butylbromide |
| Minimum Order Quantity: | 1kg |
| Price: | 2700USD/kg |
| Packaging Details: | 1.1kg/bag;25kg/drum 2. Inside: steril plastic bag+aluminum foil bag Outside: carton/drum |
| Delivery Time: | 3-7days |
| Payment Terms: | T/T, ,, L/C, D/A, D/P |
| Supply Ability: | 1000kg per year |
| Product Name: | Scopolamine Butylbromide | Appearance: | White Powder |
|---|---|---|---|
| CAS No.: | 149-64-4 | Molecular Formula: | C21H30BrNO4 |
| Shelf Life: | 24months When Properly Stored | Purity: | 99%min |
| HS Code: | 2942000000 | Function: | Digestive System Medication |
| Storage Condition: | Store In Cool&dry Place, In Well-closed Containers. | Whatsapp: | 86 15202961574 |
| High Light: | Scopolamine Butylbromide Powder,CAS 149-64-4,API Pharmaceutical Hyoscine Butylbromide |
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API Pharmaceutical CAS 149-64-4 Hyoscine Butylbromide Scopolamine Butylbromide
Scopolamine is an organic substance with the chemical formula C17H21NO4. It is a scopolamine type alkaloid found in plants in the Solanaceae family. E. Schmidt was first isolated from scopolamine in 1892. The effect is similar to atropine, its mydriasis and inhibition of glandular secretion is stronger than atropine, has an exciting effect on the respiratory center, but has an obvious inhibitory effect on the cerebral cortex, in addition to the expansion of capillaries, improve microcirculation and anti-seasickness and other effects.
Scopolamine butylbromide is a spasmolytic drug. Its main clinical indications are: preoperative preparation for gastric, duodenal and colonic endoscopy, endoscopic retrograde cholangiopanchography, pneumato-barium hypotonic angiography of stomach, duodenum and colon, and preoperative preparation for abdominal CT scan, which can reduce or inhibit gastrointestinal peristalsis. It is used for gastrointestinal spasm, biliary colic, renal colic or gastrointestinal hyperperistalsis caused by various causes. Scopolamine bubromide can relax gastrointestinal smooth muscle, relieve smooth muscle spasm, and relieve or eliminate colic caused by gastrointestinal smooth muscle spasm.
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Function:
Scopolamine butylbromide is a competitive antagonist of muscarinic acetylcholine receptor (mAChR) with an IC50 of 55.3 ± 4.3 nM.Target: mAChRScopolamine (USAN), also known as levo-duboisine and hyoscine, sold as Scopoderm, is a tropane alkaloid drug with muscarinic antagonist effects. It is among the secondary metabolites of plants from Solanaceae (nightshade) family of plants, such as henbane, jimson weed (Datura), angel's trumpets (Brugmansia), and corkwood (Duboisia). Scopolamine exerts its effects by acting as a competitive antagonist at muscarinic acetylcholine receptors, specifically M1 receptors; it is thus classified as an anticholinergic, antimuscarinic drug. Its use in medicine is relatively limited, with its chief uses being in the treatment of motion sickness and postoperative nausea and vomiting. Scopolamine is named after the plant genus Scopolia. The name "hyoscine" is from the scientific name for henbane, Hyoscyamus niger.
Product analysis report
Product name:Scopolamine Butylbromide
Batch Quantity: 200kg
Batch Number: HNB20230401
CAS No.:1115-70-4
Manufacture Date: Apr.01,2023 Analysis Date: Apr.01,2023 Expiry date: April.01 2025
Storage:Store in cool & dry place. Store in well-closed containers.
Shelf life :2 years when properly stored.
| Test | Specification | Result |
| Appearance | White crystalline powder | Complies |
| Assay,% | ≥99.0% | 99.4% |
| Loss on drying % | ≤0.5% | 0. 12 |
| Residue on ignition % | ≤0. 1% | 0.03 |
| Identification | IR | Complies |
| HPLC | Complies | |
| Heavy metal | ≤ 10ppm | 5ppm |
| Pb | ≤3ppm | 1.5ppm |
| Hg | ≤0. 1ppm | 0.05ppm |
| Cd | ≤ 1ppm | 0.2ppm |
| Single impurity | ≤0.5% | 0. 12 |
| Total impurity | ≤ 1.0% | 0.29 |
| Total bacteria | ≤ 1000cfu/g | < 1000 |
| Yeast and Mould | ≤ 100 cfu/g | < 100 |
| E.coli/25g | Absent | Absent |
| Salmonella/25g | Absent | Absent |
| Conclusion | Conforms with standards |