| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Oxazepam |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually3-5days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram，Alibaba Assurance Order |
| Supply Ability: | 5000kg/Month |
| CAS: | 604-76-1 | Mf: | C15H11ClN2O2 |
|---|---|---|---|
| MW: | 286.713 | Specification: | 99% |
| EINECS: | 210-076-9 | Appearance: | White Crystalline Powder |
| Sample: | Available | Other Name: | Dioxopromethaxine HCL |
API Pharmaceutical USP 99% Oxazepam Powder for antianxiety CAS 604-76-1
|
Product name |
Oxazepam |
|
Appearance |
White crystalline powder |
|
CAS |
604-76-1 |
|
MF |
C15H11ClN2O2 |
|
Purity |
99% |
|
Storage |
Keep in cool dry place. |
The Introductction of Oxazepam
Oxazepam is the main active metabolite of dizepam. It is a short-acting benzodiazepine, which has similar pharmacological effects to dizepam and has less impact on liver function, so it is more suitable for elderly patients or patients with liver disease.
The Application & Function of Oxazepam
1. Oxazepam is synergistic with ethanol, other sedatives, central nervous system depressants (antihistamines, barbiturates, muscle relaxants, analgesics, anesthetics, antiepileptics and clonidine) and tricyclic antidepressants when used together. The dosage of opioid analgesics should be reduced to at least half.
2, when combined with antihypertensive drugs or diuretic antihypertensive drugs, can make antihypertensive effect.
3. Combination with calcium channel blockers may aggravate hypotension.
4. Oxazepam can reduce the efficacy of carbamazepine, levodopa, oral anticoagulant and rifampicin, so the dose needs to be adjusted.
5, disulfiram, oral contraceptives, isoniazid and cimetidine can increase the blood concentration of oxazepam, and then cause toxic reactions, should avoid combined use.
6. Antacids can prolong the absorption of oxazepam.
1. Short-term treatment for anxiety disorders and anxiety-related insomnia.
2. Used to control alcohol withdrawal symptoms.
Other Name of Oxazepam
Prothanon;
Keke Min;
Dioxoprome;
Dioxoprothazine;
Dioxypromethazine;
ProMethazine Sulfone;
9,9-Dioxopromethazine;
DIOXOPROMETHAZINE HCL;
Dioxopromethaxine HCL;
Promethazine Impurity 5
The COA of Oxazepam
| ITEMS OF ANALYSIS | SPECIFICATION | RESULT |
| Appearance | White to pale yellow powder | Complies |
| Identification | IR: The IR absorption map should be consistent with that of chloroquine sulfate | Complies |
|
The reaction of Chloride |
Complies | |
| Clarify and color of solution | The solution should be clear and the color should not be darker than yellow 2 | Complies |
| Sulphate | ≤ 0.025% | 0.012% |
| pH | 4.2 - 5.1 | 4.9 |
| Related substances | Single Impurities: ≤0.5% | Complies |
| Total impurities: ≤1% | Complies | |
| Heavy Metals | ≤ 10ppm | Complies |
| Loss on drying | ≤ 0.5% | 0.35% |
| Residue on ignition | ≤ 0.1% | Complies |
| Assay(Dry based) | ≥ 99% | 99.9% |
| Conclusion | Confirm with the standard |