Place of Origin: | China |
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Brand Name: | HNB |
Certification: | ISO |
Model Number: | Steptomycin sulfate |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually3-5days |
Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order |
Supply Ability: | 5000kg/Month |
CAS: | 3810-74-0 | Mf: | C21H42N7O18S1.5 |
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MW: | 1066.19 | Specification: | 99% |
EINECS No.: | 223-286-0 | Appearance: | White Crystalline Powder |
Sample: | Available | Whatsapp: | +86 15202961574 |
Veterinary API Antibiotics 99% cas 3810-74-0 Streptomycin Sulfate
Product name |
Steptomycin sulfate |
Appearance |
White Crystalline Powder |
CAS |
|
MF |
C21H42N7O18S1.5 |
Purity |
99% |
Storage |
Keep in cool dry place. |
whatsapp:+86 15202961574
what is Streptomycin Sulfate ?
Streptomycin sulfate as an aminoglycoside antibiotic drugs.Streptomycin sulphate of n/med tuberculosis bacili have strong antibacterial effect, for most gram-positive cocci (such as all kinds of streptococcus pneumoniae) and bacillus (e.g., pseudomonas aeruginosa, anaerobic bacteria) antibacterial effect is not strong, for many gram-negative bacilli has strong antimicrobial effect, tuberculosis is effective to all kinds of skin, inhibiting the bacteria and toxins produced by function, high concentration (> 0.4 mu g/mL) have antiseptic effect.
The Introductction of Steptomycin sulfate
The function of streptomycin sulfate is to treat tuberculosis, infective endocarditis and so on. Its contraindications include pregnant population.
1. Application: Streptomycin sulfate has an antibacterial effect on mycobacterium tuberculosis and can inhibit bacterial protein synthesis. It is mostly used for infectious endocarditis and plague caused by tuberculosis, Brucella and non-hemolytic Streptomyces.
Second, contraindications: pregnant and lactating women, patients allergic to streptomycin or other aminoglycosides should not use streptomycin sulfate, in addition to patients with renal dysfunction, neurological damage and other patients with caution. In addition, the adverse effects include renal toxicity symptoms. The specific medication should follow the doctor's advice. If necessary, it is recommended to seek medical treatment in time and deal with the symptoms.
Streptomycin sulfate is the sulfate form of streptomycin, an antibiotic produced by Streptomyces griseus in the soil. Streptomycin is the most effective and least toxic antibiotic obtained by Streptomyces for extra gastrointestinal application. It is a bactericidal agent, probably by its direct action on bacterial ribosomes and inhibition of protein synthesis, mainly acting on extracellular (including intracellular) Mycobacterium tuberculosis.
Streptomycin sulfate is white or off-white powder, odorless, slightly bitter, moisture-attracting, easily soluble in water, soluble in water and more stable in nature, insoluble in ethanol or trichloromethane, stable in dry condition, airtight and protected from light for more than 4 years with constant potency, aqueous solution can be stored at room temperature pH 3-7 for 2-4 weeks, easily destroyed by acid, alkali, oxidizing agents.
Streptomycin sulfate has antibacterial effect on most Gram-positive and negative bacteria, especially on many Gram-negative bacilli such as Escherichia coli, Salmonella, Bartonella, Borrelia burgdorferi, Bacillus pneumoniae, Bacillus dysenteriae, Bacillus pneumoniae and Bacillus rhinoceros. It is the drug of choice against Mycobacterium tuberculosis and has a strong effect on Mycobacterium tuberculosis, with strong antibacterial effect at low concentration and bactericidal effect at high concentration.
The function of streptomycin sulfate is to exert its bactericidal effect by inhibiting bacterial protein synthesis. The drug belongs to the aminoglycoside class of antibiotics, and the common dosage forms are tablets and injections.
Streptomycin sulfate is mainly used in combination with other anti-tuberculosis drugs to treat various forms of tuberculosis caused by mycobacterium tuberculosis infection, as well as to treat tulafiasis alone. In addition, streptomycin sulfate can be used in combination with other antibacterial drugs to treat diseases such as brucellosis, plague, groin granuloma and rat bite fever.
Before using Streptomycin sulfate, it should be noted that it is prohibited for people who are allergic to streptomycin or other aminoglycosides, and it should be discontinued during breastfeeding. In addition, the drug may cause adverse reactions such as nephrotoxicity, neuromuscular block and ototoxicity, which requires use under the guidance of a doctor and close attention to the body's reactions during use
The Application & Steptomycin sulfate
Streptomycin sulfate is effective against both gram-positive and gram-negative bacteria, but it is less effective than penicillin G against gram-positive bacteria such as streptococci and pneumococci, and is not effective against rickettsiae, protozoa, viruses and fungi; it is more effective against Mycobacterium tuberculosis and a variety of gram-negative bacteria, such as Escherichia coli, Borrelia burgdorferi, Bacillus pneumoniae, Mycobacterium influenzae, Mycobacterium dysenteriae, Mycobacterium plague, etc.
Streptomycin sulfate is mainly used for the treatment of pulmonary tuberculosis, bone tuberculosis, lymphatic tuberculosis, intestinal tuberculosis, tuberculous meningitis caused by Mycobacterium tuberculosis and meningitis, pneumonia, septicemia, abscess chest, pleurisy, peritonitis caused by sensitive strains, and also for urinary tract and respiratory tract infections caused by sensitive strains.
Other Name of Steptomycin sulfate:
Verstrep
Strep-sol
Streptomyc
Streptomycin sulfate
Streptomycin sulphate
STREPTOMYCIN SESQUISULFATE
N'',N'''''-[(1R,2R,3S,4R,5R,6S)-4-({(2xi)-5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-threo-pentofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (salt)
2-[(1S,2R,3S,4S,5R,6S)-5-(diaminomethylideneamino)-2-[(2R,3S,4S,5R)-3-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-methylamino-oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyl-oxolan-2-yl]oxy-3,4,6-trihydroxy-cyclohexyl]guanidine
The COA of Steptomycin sulfate
Batch No.: HNB211226 |
Product Name: Steptomycin sulfate |
CAS No.: 3810-74-0 |
Quantity: 1000kg |
Man. Date: Nov., 26th, 2021 Analysis Date: Nov., 27th, 2022 Expiry Date: Nov., 25th, 2025 |
Storage: Store in cool&dry place, in well-closed containers. |
Shelf life: 36 Months when properly stored. |
Standard: USP42 |
ITEMS OF ANALYSIS | SPECIFICATIONS | RESULT |
Characteristics | White or off-white powder, hygroscopic | Complies |
Identification | A,B,C complies | Complies |
Solubility | Soluble in water, insoluble in ethanol | Complies |
pH | 4.5~7.0 | 6.5 |
Sulfate | 18.0%~21.5% | 20% |
Related Substances |
Individual impurity: ≤ 2.0% Total impurities: ≤ 5.0% |
0.5% 1.2% |
Loss on drying | ≤ 6.0% | 5.3% |
Assay(on dry basis) | ≥ 720µg/mg | 780µg/mg |
Conclusion | Complies with the USP43 standard |