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CAS 11115-82-5 Veterinary API Virginiamycin Enramycin Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Enramycin
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 11115-82-5 Mf: C106H135Cl2N26O31
MW: 2340.27 Specification: 99%
Other Name: ENDURACIDIN HYDROCHLORIDE Appearance: Grayish-brown Powder
Sample: Available Whatsapp: +86 15202961574
High Light:

99% Enramycin Powder

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Veterinary API 11115-82-5

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Enramycin Veterinary API


Product Description

Veterinary API virginiamycin CAS 11115-82-5 Enramycin Powder

CAS 11115-82-5 Veterinary API Virginiamycin Enramycin Powder 0

 

Product name

Enramycin

Appearance

Grayish-brown powder

CAS

11115-82-5

MF

C106H135Cl2N26O31

Purity

99%

Storage

Keep in cool dry place.

whatsapp:+86 15202961574

CAS 11115-82-5 Veterinary API Virginiamycin Enramycin Powder 1

 

The Introductction of Enramycin

Enramycin is produced by fermentation of actinomycetes (Streptomyces fungicidicus), and the main components are Enramycin A and B, applied in their hydrochloride form.


Enramycin is white or slightly yellowish-white powder (the crude product is gray or gray-brown powder with peculiar odor). 234~238℃ decomposition, soluble in dilute hydrochloric acid, slightly soluble in water, methanol, ethanol, insoluble in aone.


Enramycin has strong activity against Gram-positive bacteria, especially against the harmful Clostridium difficile (Clostridium) in the intestine with strong inhibition. It is not easy to produce resistance after long-term use, because it changes the bacterial group in the intestinal tract, so it has good effect on the utilization of nutrients in the feed, which can promote the weight gain of pigs and chickens and improve the feed conversion rate.

 

Enramycin hydrochloride has excellent stability to heat, light and moisture. Enramycin has high stability in feed, little degradation in long term storage at room temperature, also very stable in the process of making pellets, and little decrease in potency after mixing with feed in long term storage at room temperature. Enramycin is not degraded in the intestinal tract and can maintain its original antibacterial activity.

 
1) Enlamycin has a strong effect on gram-positive bacteria, and the main mechanism is to inhibit the synthesis of bacterial cell walls. The main component of the bacterial cell wall is mucopeptide, which accounts for 65-95% of the total cell wall in Gram-positive bacteria. Enlamycin can prevent the synthesis of mucopeptide, make the cell wall defect, lead to increased osmotic pressure in the cell, and the extracellular fluid penetrates into the bacteria, causing the bacteria to deform and swell, rupture and death. Enramycin mainly acts on the fission stage of bacteria, not only bactericidal, but also bacteriolytic. The minimum inhibitory concentration is 0.05-3.13μg/ml.
 
2) The antibacterial ability of enlamycin against Clostridium percapsulens, which is widespread in feed, can damage the small intestine, aggravate the severity of coccidiosis, and reduce the production performance of livestock and poultry. It is one of the main causes of wet stool, necrotizing enteritis and diarrhea in pigs. Has become a universal concern of the world. In the test of Clostridium perfringens isolated from several growth-promoting antibiotics, it was found that enlamycin had the strongest antibacterial ability, and no drug-resistant strains were found.
 
Advantage of enramycin
1) The microaddition of enramycin in the feed can play a good role in promoting growth and significantly increasing feed reward.
2) Enramycin showed good antibacterial action against gram-positive bacteria under both aerobic and anaerobic conditions. Enlamycin is extremely effective against Clostridium perfringens, which is the main cause of growth inhibition and necrotizing enteritis in pigs and chickens.
3) There is no cross-resistance to enramycin.
4) The development of resistance to enlamycin is very slow, and no enlamycin resistant Clostridium perfringens has been isolated.
5) Because enramycin is not absorbed in the intestine, there is no need to worry about drug residues, and there is no withdrawal period.
6) Enlamycin is stable in the feed and remains active even during the processing of pellets.
7) Enlamycin can reduce the situation of chicken stool.
8) Enlamycin can inhibit ammonia producing microorganisms, thus reducing the ammonia concentration in the intestines and blood of pigs and chickens, thereby reducing the ammonia concentration in the livestock house.
9) Enlamycin can reduce the clinical symptoms of coccidiosis, probably because Enlamycin has a strong inhibitory effect on the anaerobic bacteria of secondary infection.
 
 

The Application & Function of Enramycin

Advantage of Enramycin

1. Enramycin, when added in trace amounts to feeds, can provide good growth promotion and significantly increase feed remuneration.
2. Enramycin shows good antimicrobial activity against gram-positive bacteria both in aerobic and anaerobic conditions. Enramycin has a strong effect on Clostridium perfringens, which is the main cause of growth inhibition and necrotizing enteritis in pigs and chickens.
3. Enramycin is not yet cross-resistant.
4. Enramycin develops resistance very slowly and Clostridium perfringens resistant to enramycin has not been isolated.
5. Because Enramycin is not absorbed in the intestinal tract, there is no need to worry about drug residues and there is no withdrawal period.
6. Enramycin has stable performance within the feed and remains active even during processing of pellets.
7) Enramycin can reduce the situation of chickens excreting scanty feces.
8. Enramycin can inhibit ammonia-producing microorganisms, thus reducing ammonia concentration in the intestines and blood of pigs and chickens, and thus reducing ammonia concentration in the barn.
9. Enramycin reduces the clinical signs of coccidiosis, probably due to the extremely strong inhibitory effect of enramycin on secondary infecting anaerobic bacteria.

 

Effect on chickens
Enramycin is effective in promoting growth and improving feed remuneration for both broilers and laying hens.
Effectiveness in preventing watery stool
(1) Chickens may have watery stools due to the disturbance of intestinal flora. Enramycin mainly acts on the intestinal flora, which can improve the bad condition of watery stool.
(2) Enramycin can enhance the anticoccidial activity of anticoccidial drugs or reduce the occurrence of coccidiosis.

 

Efficacy on pigs
Enramycin mixing has the effect of promoting growth and improving feed remuneration for both piglets and finishing pigs.
According to the results of several tests, the recommended dose for pigs is 2.5-10ppm.
Prevention of dysentery. Adding Enramycin to piglet opening feed can not only promote growth and improve feed remuneration. It can also reduce the occurrence of dysentery in piglets.

 

Aquatic application effect
Adding 2,6,8ppm Enramycin to the bait can significantly increase the daily weight gain of fish and reduce the bait coefficient.

 

Other Name of Enramycin

Enradin
Enramycin
Enramicina
Enduracidin
Enramycinum
Enramycinum [inn-latin]
Enramycinum [INN-Latin]
Enramicina [inn-spanish]
enduracidin hydrochloride

 

The COA of Enramycin

 

TEST ITEMS SPECIFICATIONS RESULT
Characteristics White or off-white powder Complies
Identification HPLC: The retention time of the two main peaks in the test solution should be the same as that of the corresponding two main peaks in the control solution. Complies
IR: The infrared absorption spectra of this product should be consistent with those of the Cloxacillin control product treated by the same method Complies
Solubility soluble in dilute hydrochloric acid, slightly soluble in water, methanol, ethanol, insoluble in acene Complies
Loss on drying ≤ 1.0% 0.35%
Residue on ignition ≤ 0.1% 0.07%
Heavy metals ≤10ppm Complies
Related Substances Single Impurity: ≤ 0.1% Complies
Total Impurities: ≤ 0.5% 0.18%
Assay (Dry Based) ≥ 98% 99.5%
Conclusion Complies with the USP standard

Contact Details
Gary Liu

Phone Number : +8615202961574

WhatsApp : +8618629242069