CAS: | 53123-88-9 | Mf: | C51H79NO13 |
---|---|---|---|
Molecular Weight: | 914.172 | Specification: | ≥99% |
Appearance: | White Or Off-white Powde | Whatsapp: | +86 15202961574 |
Veterinary API CAS 53123-88-9 Rapamycin Powder
Prodcut name | Rapamycin |
MOQ | 1KG |
CAS No. | 53123-88-9 |
Appearance | White to off-white Powder |
Molecular Formula | C51h79no13 |
Molecular Weight | 914.19 |
Assay | 99% |
The Introductction of Rapamycin :
Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and to treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It inhibits activation of T cells and B cells by reducing the production of interleukin-2 (IL-2)..
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The Application & Function of Rapamycin :
Function of rapamycin
Anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties.
Application of rapamycin
Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins.
Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway..