Place of Origin: | China |
---|---|
Brand Name: | HNB |
Certification: | ISO |
Model Number: | Oxyclozanide |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually3-5days |
Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order |
Supply Ability: | 5000kg/Month |
CAS: | 2277-92-1 | Mf: | C13H6Cl5NO3 |
---|---|---|---|
MW: | 401.46 | Specification: | 99% |
EINECS: | 218-904-0 | Appearance: | Off-white Powder |
Sample: | Available |
CAS 2277-92-1 Pharmaceutical Grade 99% Oxyclozanide Antiparasitic API Powder
Product name |
Oxyclozanide |
Appearance |
Off-white powder |
CAS |
2277-92-1 |
MF |
C13H6Cl5NO3 |
Purity |
99% |
Storage |
Keep in cool dry place. |
The Introductction of Oxyclozanide
The powder of Oxyclozanide is off-white or beige, odorless or almost odorless. It is insoluble in water, soluble in aceton*
, soluble in ethanol (96%), slightly soluble in chloroform. In the production process of the preparation, the water insolubility and other characteristics of the drug should be fully taken into account, and the suspension preparation is often used in foreign countries, which not only solves the above problems, but also improves the bioavailability of the drug to a certain extent. Pentachlorolimus has a high melting point of about 208℃. It has the maximum light absorption at 300 nm in the ultraviolet region with an absorbance of 0.76, which provides a reference for its content determination.
Oxyclozanide, as the drug of choice for clinical anthelmintic infections, has excellent properties such as broad-spectrum, low toxicity and low residue. The chemical name is 2,3,5-dichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide. Pentachlorolimus, as a chemical synthetic drug against helminth infections, has excellent properties such as broad spectrum, low toxicity, low residue, etc. It is the first choice of clinical anti-helminth infections as it is effective in the treatment of helminth infections such as trematode and tapeworm, and there is no report of related drug resistance so far.
The Application & Function of Oxyclozanide
Oxyclozanide has good efficacy in the process of antihelminthic infections, especially in the treatment of liver flake trematode infections, and there is no drug resistance phenomenon, it is the first choice of antihelminthic drugs.
Oxyclozanide can also be used to treat roundworm and tapeworm infections.
Oxyclozanide as the main drug for the treatment of liver flukes, it has been widely used in foreign countries, there are tablets, oral suspension, compound tablets, compound suspension and other products on the market.
Other Name of Oxyclozanide
Oxycloxanide
OXYCLOZANIDE BPV
OXYCLOZANIDE B.P
BPV OXYCLOZANIDE BPV
3,3',5,5',6-pentachloro-2,2'-dihydroxybenzanilide
2,2'-dihydroxy-3,3',5,5',6-pentachlorobenzanilide
2,3,5-TRICHLORO-N-(3,5-DICHLORO-2-HYDROXYPHENYL)-6-HYDROXYBENZAMIDE
2,3,5-trichloro-n-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-benzamid
2,3,5-trichloro-N-(3,5-dichloro-2-hydroxy-phenyl)-6-hydroxy-benzamide
The COA of Oxyclozanide
Product Name: | OXYCLOZANIDE VET BP85 | ||
Batch No.: | HNB20230720 | Manufacture Date: | Jul-20-2023 |
Batch Size: | 25kg/drum | Analysis Date: | Jul-21-2023 |
Batch: | 1300kg | Expiry Date: | Jul-19-2026 |
Storage: | Store in cool & dry place, in well-closed containers. | ||
Shelf life: | 36 Months when properly stored. |
ITEMS OF ANALYSIS | SPECIFICATIONS | RESULT |
Appearance | A pale cream or cream coloured powder | Complies |
Solubility | Very Slightly soluble in water, Freely soluble in aceton*, soluble in ethanol(96%) Slightly soluble in Chloroform | Complies |
Identification | IR: The infrared absorption spectrum of sample should concordant with the spectrum of Oxyclozanide Standard | Complies |
UV: The light absorption of 0.003% solution of test sample in the range 250-350 nm exhibits absorption maxima at 300nm about 0.76 | Complies | |
Melting point | About 208°C | 208.0°C~210.0°C |
Ionisable Chlorine(% w/w) | Not more than 0.25 | 0.18% |
Loss on drying(% w/w) (at 60°C under vacuum) |
Not more than 1.0 | 0.37% |
Sulphated ash(% w/w) | Not more than 0.2 | 0.07% |
Related substances by HPLC(%) | ||
Before main peak | Not more than 0.3% | 0.18% |
After main peak | Not more than 1.0 | 0.48% |
Assay(% w/w) (On dried bass) |
Between 98.0% and 101.0 | 99.61% |
Conclusion: The material conforms with the BP VET specification |