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99% Finasteride Powder Anti Hair Lossing Ingredients CAS 98319-26-7

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Finasteride
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 98319-26-7 Mf: C23H36N2O2
Grade: Cosmetic Grade; Specification: 99%
MW: 372.54 Appearance: White Crystalline Powder
Sample: Available
High Light:

99% Finasteride Powder

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CAS 98319-26-7 Cosmetics Raw Materials

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Anti Hair Lossing Finasteride Powder


Product Description

Cas 98319-26-7 Anti-Hair Lossing Ingredients 99% Finasteride Powder

99% Finasteride Powder Anti Hair Lossing Ingredients CAS 98319-26-7 0

Product name

Finasteride

Appearance

White Crystalline Powder

CAS

98319-26-7

MF

C23H36N2O2

Purity

99%

Storage

Keep in cool dry place.

99% Finasteride Powder Anti Hair Lossing Ingredients CAS 98319-26-7 1

 

The Introduction of Finasteride

 

Finasteride, with the chemical formula C23H36N2O2, is a 4-azasteroid compound. It is a specific inhibitor of intracellular enzyme II type 5a reductase in the process of test*sterone metabolism to dihydrotest0sterone. It can effectively reduce dihydrotest0sterone in the blood and prostate by inhibiting the conversion of test0sterone to dihydrotest0sterone (DHT), reducing prostate volume and improving symptoms, increasing urinary flow rate, and preventing benign prostatic hyperplasia (BPH).


Finasteride is a white or almost white crystalline solid. Easily soluble in chloroform, dimethyl sulfoxide, ethanol, methanol or n-propanol, insoluble in propylene glycol or polyethylene glycol 400, very slightly soluble in 0.1mol/ChemicalbookL hydrochloric acid, 0.1mol/L sodium hydroxide solution or water. The melting point is about 257 ℃; There is also a melting point of 252-254 ℃. [ α] D-59 ° (C=l, methanol).


Finasteride is a basic drug used in the treatment of benign prostatic hyperplasia and prostatitis in China. It is a synthetic 4-nitrosteroid hormone compound that belongs to the class of resistant hormone drugs and can selectively inhibit 5 α– Reductase, which converts testoster0ne into 5 α– The process of dihydrotestoster0ne (DHT) becomes blocked, the levels of male hormones in prostate cells decrease, the prostate specific antigen in serum decreases, the enlarged prostate volume decreases, and the urine flow rate increases, thereby alleviating the symptoms of patients and achieving the goal of treating prostate hyperplasia. The characteristic of this drug is its ability to selectively block the stimulating effect of androgens on the prostate. Prostate hyperplasia, also known as prostate enlargement, causes compression of the bladder neck and posterior urethra, causing urinary tract obstruction and other symptoms and complications, causing deep pain to patients. It is more common in men over the age of 50.

 

Finasteride is also a type of 5 α– A specific inhibitor of reductase, belonging to the class of resistant hormone drugs, which can prevent the conversion of testoster0ne to dihydrotestoster0ne, thereby reducing the synthesis of dihydrotestoster0ne, reducing the content of dihydrotestoster0ne in scalp hair follicles and serum, restoring the hair growth function of already suppressed hair follicles and nipples, promoting hair growth and preventing further hair loss. Finasteride is currently the only oral drug approved by the US Food and Drug Administration FDA for the treatment of male type hair loss, The recommended dose is 1mg per dose.

 

The Application & Function of Finasteride

 

Finasteride is used to treat prostate enlargement and baldness in men.

 

Other Name of Finasteride:

mk-0906
proscar
l-652,931
finasteride
17beta-(n-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one
n-tert-butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide
n-(2-methyl-2-propyl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide
(5alpha,17beta)-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5alpha,17beta
(5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5-alpha,17-be
(4aR,4bS,6aS,7S,9aS,9bS)-N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
(4aR,4bS,6aS,9aS,9bS,11aR)-N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide

 

The COA of Finasteride

 

Product Name: Finasteride

CAS No.: 98319-26-7

Batch No.: HNB20230418

Batch Size: 50kg

Manufacture Date: Apr., 18th, 2023     Analysis Date: Apr., 19th, 2023     Expiry date: Apr., 17th, 2025

Storage: Store in cool&dry place, in well-closed containers.

Shelf life: 24 Months when properly stored.

 

ITEMS SPECIFICATIONS RESULT
Appearance White or almost white crystalline powder Complies
Solubility Free soluble in chloroform and in alcohol,very slightly soluble in water Complies
Identification (IR,HPLC) Complies with the standard Complies
Melting point About 257℃ 256.0℃-257.0℃
Specific rotation -56.0°~-60.0° -58.4°
Water ≤0.3% 0.25%
Residue on ignition ≤0.1% 0.04%
Heavey metals ≤10ppm <10ppm
Loose density(g/cm3) 0.27~0.37 0.31
Tapped dinsity(g/cm3) 0.40~0.56 0.52
Particle size 100%≤20um,90%≤10um Complies
Any individual impurity ≤0.5% 0.12%
Total impurities ≤1.0% 0.44%
Assay(HPLC) 98.5%~101.0% 99.2%
Aceton* ≤5000ppm Complies
Chloroform ≤60ppm Complies
THF ≤720ppm Complies
Dichloromethane ≤600ppm Complies
Toluene ≤890ppm Complies
Methanol ≤3000ppm Complies
Organic volatile substances Meet the ICH requirements Complies
Conclusion Conform with the Standard

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