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Antipyretic Analgesic Cas 15687-27-1 NSAID Brufen Ibuprofen

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Ibuprofen powder
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 15687-27-1 Mf: C13H18O2
MW: 206.28 Specification: ≥98%
Einecs No.: 239-784-6 Appearance: White Crystalline Powder

Product Description

Antipyretic Analgesic Cas 15687-27-1 NSAID Brufen Ibuprofen

Antipyretic Analgesic Cas 15687-27-1 NSAID Brufen Ibuprofen 0

 

Product Name

Ibuprofen

Synonyms

RARECHEM AL BO 0989;MOTRIN(TM);(+/-)-2-(4-ISOBUTYLPHENYL)-PROPIONIC ACID;2-(4-ISOBUTYLPHENYL)PROPIONIC ACID;4-ISOBUTYL-ALPHA-METHYLPHENYLACETIC ACID;AKOS NCG1-0060;(+/-)-ALPHA-METHYL-4-(2-METHYLPROPYL)-BENZENEACETIC ACID;ALPHA-METHYL-4-[2-METHYLPROPYL]BENZENEACETIC ACID

CAS

15687-27-1

MF

C13H18O2

MW

206.28

EINECS

239-784-6

Product Categories

Active Pharmaceutical Ingredients;API;APIs;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Lipid signaling;Isotopically Labeled Pharmaceutical Reference Standard;ADVIL;Other APIs;Pharmaceutical ingredients;pharmacetucial intermediate

 

The Introductction of Ibuprofen powder:

 

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used for relief of symptoms of arthritis, fever, as an analgesic (pain reliever), especially where there is an inflammatory component, and dysmenorrhea.

Ibuprofen is known to have an antiplatelet effect, though it is relatively mild and short-lived when compared with aspirin or other better-known antiplatelet drugs.

 

Ibuprofen belongs to a non-steroidal anti-inflammatory analgesic. It has excellent anti-inflammatory, analgesic and antipyretic effect with less adverse reactions. It has been widely used in the world, as the world's best-selling non-prescription drugs. It, together with aspirin and paracmol are listed as the three key antipyretic analgesics products. In our country, it is mainly used in pain alleviation and anti-rheumatism, etc. It has much less applications in the treatment of cold and fever compared with paracol and aspirin. There are a dozens of pharmaceutical companies qualified for production of ibuprofen in China. But the bulk of the domestic market sales of ibuprofen have been occupied by Tianjin Sino-US Company.
The Ibuprofen was co-discovered by Dr. Stewart Adams (later he becomes a professor and won the Medal of the British Empire) and his team including CoLinBurrows and Dr. John Nicholson. The aim of the initial study was to develop a "super aspirin" to obtain an alternative for the treatment of rheumatoid arthritis that is comparable to that of aspirin but with less serious adverse reactions. For other drugs such as phenylbutazone, it has a high risk of causing adrenal suppression and other adverse events such as gastrointestinal ulcers. Adams decided to look for a drug with good gastrointestinal resistance, which is particularly important for all non-steroidal anti-inflammatory drugs.
Phenyl acetate drugs have aroused people's interest. Although some of these drugs have been found to be at risk of causing ulcers based on the dog's test, Adams is aware of that this phenomenon may be due to a relatively long half-life of the drug clearance. In this class of drugs there is a compound - ibuprofen, which has a relatively short half-life, sustaining only 2 hours. Among the screened alternative drugs, although it is not the most effective, it is the most secure. In 1964, ibuprofen had become the most promising alternative to aspirin.

 

The Application & Function of Ibuprofen powder:

 

1.Ibuprofen is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis and rheumatoid arthritis.

 

2.It is also used to relieve mild to moderate pain, including menstrual pain. Nonprescription

 

3.ibuprofen is used to reduce fever and to relieve mild pain from headaches, muscle aches, arthritis, menstrual periods, the common cold, toothaches, and backaches.

 

Mainly used in clinical arthritis, mild to moderate pain, dysmenorrhea, gout, and so on. The gastrointestinal irritation than aspirin light.

 

Ibuprofen for rheumatoid arthritis, rheumatoid arthritis, osteoarthritis pain, joint swelling, limited mobility and other symptoms result is better.

 

The COA of Ibuprofen powder:

 

ITEM

SPECIFICATION

RESULT

Appearance

White, crystalline powder or colorless crystals

Conforms

Identification

Accord With BP2007

Conforms

Assay

98.5%~101.0%

99.97%

Melting point

75°C~78°C

77°C

Optical rotation

-0.05°~+0.05°

0.00°

Heavy metals

≤ 0.001%

<0.001%

Related substances

Impurity B

≤ 0.3%

Conforms

Any other impurity

≤ 0.3%

Conforms

Total of all impurities apart from impurity B

≤ 0.7%

Passes

Impurity F

≤ 0.1%

Not detected

Sulphated ash

≤ 0.1%

0.02%

Appearance of solution

Accord With BP2007

Conforms

Contact Details
Gary Liu

Phone Number : +8615202961574

WhatsApp : +8618629242069