CAS 73-31-4 Pharmaceutical API Melatonine Powder Sleep Improve

Melatonin (MT) is a hormone secreted by the brain's pineal gland. Melatonin belongs to the indole heterocyclic compound, its chemical name is n-acetyl-5-methoxytryptamine, also known as pineal hormone, melatonin, melatonin. Melatonin is synthesized and stored in the pineal gland, where sympathetic excitation innervates pineal cells to release melatonin. The secretion of melatonin has an obvious circadian rhythm, which is suppressed during the day and active at night. Melatonin can inhibit the hypothalamic-pituitary-gonadal axis, reduce the contents of gonadotropin releasing hormone, gonadotropin, luteinizing hormone and follicular , and directly act on the gonads to reduce the contents . In addition, MT has strong neuroendocrine immunomodulatory activity and free radical scavenging antioxidant ability, which may become a new antiviral therapy method and pathway. MT is ultimately metabolized in the liver, and damage to liver cells can affect the level of MT in vivo .

The well-known function of melatonin is mainly to improve sleep quality (dosage 0.1-0.3 mg), shorten the time to wake up before bedtime and to fall asleep, improve sleep quality, significantly reduce the number of awakenings during sleep, short light sleep stage, prolonged deep sleep stage, and lower arousal threshold the next morning. It has a strong function of adjusting time difference .

The best thing about melatonin is that it is the strongest endogenous free radical scavenger ever discovered. The basic function of melatonin is to participate in the antioxidant system, preventing oxidative damage to cells. In this respect, it surpasses all known substances in the body. The latest research proves that MT is the endocrine commander-in-chief, which controls the activity of various endocrine glands in the body. Which indirectly controls the functions of our whole body.