|Place of Origin:||China|
|Minimum Order Quantity:||1KG|
|Packaging Details:||1.1kg/bag;25kg/drum 2. Inside: steril plastic bag+aluminum foil bag Outside: carton/drum|
|Payment Terms:||T/T, Western Union,, L/C, D/A, D/P|
|Supply Ability:||1 Metric tons per month|
|Product Name:||Sitagliptin||Appearance:||White Powder|
|CAS No.:||486460-32-6||Molecular Formula:||C16H15F6N5O|
|Shelf Life:||24months When Properly Stored||Purity:||99%min|
|HS Code:||2933990099||Function:||Regulating Blood Lipids|
|Storage Condition:||Store In Cool&dry Place, In Well-closed Containers.|
API Active Pharmaceutical Ingredient,
Human API Pharma Ingredients
Human API Regulating Blood Lipids Drugs Sitagliptin Powder CAS 486460-32-6
Sitapliptin is a dipeptidyl peptidase-4 (DPP-4) suppressor that controls blood sugar levels by protecting and enhancing the action of endogenous gut glucogenin. Glucose-dependent insulin-releasing stimulating peptide (GIP) and glucagon-like peptide-1 (GLP-1) are intestinal hypoglycemic hormones released in response to dietary intake.
Sitapliptin inhibits the degradation of intestinal glucagon via DPP-4, thereby enhancing the function of GLP-1 and GIP, increasing insulin release and reducing circulating glucagon levels in a glucose-dependent manner. The drug selectively inhibited DPP-4, but had no inhibitory activity on DPP-8 or DPP-9.
Product analysis report
Batch No.: HNB20230205
Product Name: Sitagliptin
Manufacture Date: 05th,Feb.,2023 Analysis Date: 05th,Feb.,2023 Expiry Date: 04th,Feb.,2025
Storage: Store in cool&dry place, in well-closed containers.
Shelf life: 24 Months when properly stored.
|Inspection Standard||Enterprise Standard Nutraceuticals Grade|
|Description||white powder||White powder|
|Identification IR||Similar with the Reference Spectrum||Complies|
|Optical Rotation||- 15.5° ~ - 17.5°||- 16.3°|
|Clearity and color of solution||Clear and colourless||Clear and colourless|
|Heavy Metals||Not more than 10ppm||Complies|
|Arsenic||Not more than 1ppm||Complies|
|Sulphates||Not more than 300ppm||Complies|
|Ammonium||Not more than 200ppm||Complies|
|Iron||Not more than 10ppm||Complies|
|Cadmium||Not more than 1ppm||Complies|
|Lead||Not more than 3ppm||Complies|
|Mercury||Not more than 0. 1ppm||Complies|
|Related Substances||Total||Not more than 2.0%||0.9%|
|GSSG||Not more than 1.5%||0.3%|
|Loss on Drying||Not more than 0.5%||0.2%|
|Residue on Ignition||Not more than 0. 1%||0.04%|
|Assay||98.0% to 101.0%||99.0%|
|Total plate count||≤1000cfu/g||Complies|
|Yeast and mold count||≤100cfu/g||Complies|
|Total coli forms||≤100cfu/g||Complies|
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