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Anticoagulants API Pharmaceutical 99% Heparin Sodium Powder CAS 9041-08-1

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Heparin Sodium
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 9041-08-1 CAS: 9041-08-1
Mf: (C14H25NO20S3)n.xNa Mf: (C14H25NO20S3)n.xNa
MW: 6117 MW: 6117
Specification: 99% EINECS: 232-681-7
Appearance: White Crystalline Powder Sample: Available
High Light:

CAS 9041-08-1 Heparin Sodium Powder

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Heparin Sodium API Pharmaceutical

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Anticoagulants Heparin Sodium Powder


Product Description

Pharmaceutical API Anticoagulants Raw Material 99% Heparin Sodium Powder CAS 9041-08-1

Anticoagulants API Pharmaceutical 99% Heparin Sodium Powder CAS 9041-08-1 0

Product name

Heparin Sodium

Appearance

White crystalline powder

CAS

9041-08-1

MF

(C14H25NO20S3)n.xNa

Purity

99%

Storage

Keep in cool dry place.

Anticoagulants API Pharmaceutical 99% Heparin Sodium Powder CAS 9041-08-1 1

 

The Introductction of Heparin Sodium

Heparin sodium is an anticoagulant, a mucopolysaccharide, which is the sodium salt of glucosamine sulfate extracted from the intestinal mucosa of pigs, cattle and sheep, and is secreted by mast cells in the human body and exists naturally in the blood. Heparin sodium has the functions of preventing platelet aggregation and destruction, inhibiting the conversion of fibrinogen into fibrin monomer, inhibiting the formation of thrombin and counteracting the formed thrombin, preventing the conversion of prothrombin into thrombin and counteracting thrombin, etc.


Heparin sodium is white or off-white powder, odorless, moisture-attracting, easily soluble in water, insoluble in ethanol, aceton* and other organic solvents. It has a strong negative charge in aqueous solution and can combine with some cations to form molecular complexes. The aqueous solution is more stable at pH 7.

 

The Application & function of Heparin Sodium

Heparin sodium delays or prevents blood clotting in vitro and in vivo. Its mechanism of action is extremely complex and has an effect on many parts of the coagulation process.
Its effects are.
(1) Inhibit the formation and action of thrombin, thus preventing thrombinogen from becoming thrombin;
(2) Inhibit the role of thrombin and other coagulation factors at higher concentrations and prevent fibrinogen from becoming fibrin;
3) It can prevent the agglutination and destruction of platelets, etc. In addition, the anticoagulant effect of sodium he-parin is also related to its negatively charged sulfate in the molecule, and positively charged alkaline substances such as fish protein or toluidine blue can neutralize its negative charge, so it can inhibit its anticoagulant effect.
(4) Since heparin can activate and release lipoprotein esterase in the body, which can hydrolyze triglycerides and LDL of celiac particles, it also has a hypolipidemic effect.

 

Other Name of Heparin Sodium

 

SODIUM HEPARIN;SODIUM HEPARINATE;REVIPARIN SODIUM;PORCINE HEPARIN SODIUM;BOVINE HEPARIN SODIUM; BOVINE;HEP, NA, PORCINE;HEPARIN PORCINE SODIUM SALT

 

The COA of Heparin Sodium

 

Batch No.: HNB230124
Product Name: Heparin Sodium
CAS No.: 9041-08-1
Manufacture Date: Jan.23th,2023                    Expiry Date: Jan.22th,2025
Sample Date: Jan.22th,2023                            Analysis Date: Jan.24th,2023
Storage: Store in cool&dry place, in well-closed containers.
Shelf life: 24 Months when properly stored.
Reference standard: USP43
ITEMS OF ANALYSIS SPECIFICATIONS RESULT
Appearance White or almost white powder Complies
Identification Pass Complies
Specific optical rotation ≥+50.0° +52.3°
Total N 1.3%~2.5% 2.1%
Loss on drying ≤5.0% 1.38%
Heavy metals ≤30ppm Complies
Residue on ignition 28.0%~41.0% 32%
Na 10.5%~13.5% 12.3%
Any other single impurity N.M.T.0.10% No detected
Total impunities N.M.T. 1.0% No detected
Bacterial endotoxins <0.010EU Complies
Assay The potency of each 1mg of anti-factor IIa should not be less than 180IU, and the potency ratio of anti-factor Xa to anti-factor IIa should be 0.9~1.1 Complies
Conclusion

Up to the standard

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