99% purity Nitrofurantoin CAS 67-20-9
|Yellow Crystal Powder
|Keep in cool dry place.
The Introductction of Nitrofurantoin :
Nitrofurantoin, sold under the trade name Macrobid among others, is an antibiotic used to treat bladder infections.It is not
effective for kidney infections. It is taken by mouth. Common side effects include nausea, loss of appetite, diarrhea, and headaches. Rarely numbness, lung problems, or liver problems may occur. It should not be used in people with kidney problems.While it looks like it is generally safe during pregnancy it should not be used near delivery.It works by slowing growth rather than killing bacteria.
The Application & Function of Nitrofurantoin :
Application of Nitrofurantoin
Nitrofurantoin has been available for the treatment of urinary tract infections (UTIs) since 1953. Its current uses include the treatment of uncomplicated UTIs and prophylaxis against UTIs in people prone to recurrent UTIs. Increasing bacterial antibiotic resistance to other commonly used agents, such as fluoroquinolones and trimethoprim/sulfamethoxazole, has led to increased interest in using nitrofurantoin.
Several trials comparing nitrofurantoin to other commonly used agents have shown this drug results in similar cure rates for uncomplicated UTIs.The efficacy of nitrofurantoin in treating UTIs combined with a low rate of bacterial resistance to this agent makes it one of the first-line agents for treating uncomplicated UTIs as recommended by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases.Nitrofurantoin is not recommended for the treatment ofpyelonephritis,prostatitis and intra-abdominal abscess,because of extremely poor tissue penetration and low blood levels. It is used in the treatment of infections caused by these organisms.Function of NitrofurantoinThe mechanism of action of nitrofurantoin is unique and complex. The works by damaging bacterial DNA, since its reduced form is highly reactive.This is made possible by the rapid reduction of nitrofurantoin inside the bacterial cell by flavoproteins
(nitrofuran reductase) to multiple reactive intermediates that attack ribosomal proteins, DNA,respiration, pyruvate metabolism and other macromolecules within the cell. Nitrofurantoin exerts greater effects on bacterial cells than mammalian cells because bacterial cells activate the more rapidly. It is not known which of the actions of nitrofurantoin is primarily responsible for its bactericidal activity. The broad mechanism of action for this likely is responsible for the low development of resistance to its effects, as the drug affects many different processes important to the bacterial cell.
HNB Biotech company details
Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian
International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the
leading researcher and one of the biggest manufacturer in high technology API area.
There are 8 experts in our research team. We insist in innovation and produce high quality
products. And GMP standard workshop and complete stainless extraction equipment.
We have 2 sales departments over 20 people and sell our products all over the world.
We also have strong professional research and development team, talented personnel and
completely equipped laboratory for the quality controlling. Various Detection Device is
equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto
titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.
HNB mainly engaged in export of products including, without limitation, pharmaceutical raw
materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant
extract, feed and food additives.
Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and
Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends
from both home and abroad.
Passion to innovate, Power to deliver !