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Pharmaceutical Chemicals Panadol Acetaminophen CAS 103-90-2 Paracetamol Raw Material

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Panadol Acetaminophen/ Paracetamol
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability: 5000kg/Month
Detail Information
Mf: C8H9NO2 CAS: 103-90-2
Specification: ≥99% MW: 151.163
Appearance: White Powder Density: 1.3±0.1 G/cm3
Flashing Point: 188.4±23.2 °C Melting Point: 168-172 °C(lit.)
EINECS: 203-157-5

Product Description

Pharmaceutical Chemicals Panadol Acetaminophen CAS 103-90-2 Paracetamol Raw Material

 

Pharmaceutical Chemicals Panadol Acetaminophen CAS 103-90-2  Paracetamol Raw Material 0

Prodcut name Acetaminophen
Acetaminophen Paracetamol
MOQ 1KG
CAS No. 103-90-2
Appearance White Powder
Molecular Formula C8H9NO2
Molecular Weight 151.16
Assay 99%
Application Pharma grade


The Introductction of Acetaminophen:

 

Acetaminophen is an acetanilid antipyretic analgesic. By inhibiting cyclooxygenase, selectively inhibiting the synthesis of prostaglandin in the hypothalamic body temperature regulation center, leading to peripheral vasodilation and sweating to achieve antipyretic effect, the intensity of antipyretic effect is similar to aspirin; by inhibiting the synthesis of prostaglandins, etc. And release, increase the pain threshold and play an analgesic role, which belongs to peripheral analgesics, the effect is weaker than aspirin, only effective for mild to moderate pain.

 

The Application & Function of Acetaminophen:

 

Function :

1.Paracetamol is the most commonly used non-anti-inflammatory antipyretic analgesics, antipyretic effect similar analgesic effect is weak, no anti-inflammatory anti-rheumatic effects, acetanilide drugs is the best varieties. Particularly suitable for patients who can not use carboxylic acids. For cold, toothache embolism. Acetaminophen is also an intermediate for organic synthesis, hydrogen peroxide stabilizer, and photographic chemicals.

 

2.Paracetamol for antipyretic, analgesic, anti-rheumatic drugs

 

3.Paracetamol for organic synthesis intermediates, hydrogen peroxide stabilizer, photographic chemicals, non-anti-inflammatory antipyretic analgesics.

 

Application:

 

Paracetamole is approved for reducing fever in people of all ages. Paracetamole is used for the relief of pains associated with many parts of the body. It has analgesic properties comparable to those of aspirin, while its anti-inflammatory effects are weaker. It is better tolerated than aspirin in patients in whom excessive gastric acid secretion or prolongation of bleeding time may be a concern.

 

 

The COA of Acetaminophen:

 

Tests Standards Results
Appearance White or almost white ,crystalline powder. White,crystalline powder.
Identification A:IR absorption Complies
  B:UV absorption Complies
  C:TLC Complies
Melting point 168~172°C 169.0~170.9°C
Water Not more than0.5% 0.08%
Related substance ImpurityJ(chloroacetanilide)not more than 10 ppm 2ppm
  Impurity K(4-aminophenolly)not more than 50 ppm 15 ppm
  Impurity F(4-nitrophenolly)not more than 0.05% Not detected
  any other impurity not more than 0.05% 0.01%
  Total of other impurities not more than 0.1% 0.02%
Residue on ignition Not more than 0.1% 0.05%
Chloride Not more than 0.014% Less than 0.014%
Sulfate Not more than 0.02% Less than 0.02%
Sulfide Conforms Conforms
Heavy metals Not more than 0.001% Less than 0.001%
Free p-aminophenol Not more than 0.005% Less than 0.005%
Limit of P-chloroacetanilide Not more than 0.001% Less than 0.001%
Readily carbonizable substances Conforms Conforms
Residual solvents Residual content of acetic acid is limited by the test of loss on dryingnot more than0.5% 0.08%
Assay(anhydrous basis) 99.0~101.0% 99.6%
Conclusion: Complies with USP34/ BP2011

 

 

 

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