products

Antibiotic Antiparasitic Drug Ivermectin Powder For Anti-Leishmaniasis CAS 70288-86-7

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO9001
Model Number: Ivermectin
Minimum Order Quantity: 1kg
Price: 280USD/kg
Packaging Details: 1.1kg/bag;25kg/drum 2. Inside: steril plastic bag+aluminum foil bag Outside: carton/drum
Delivery Time: 3-7days
Payment Terms: T/T, Western Union,, L/C, D/A, D/P
Supply Ability: 10Metric tons per month
Detail Information
Product Name: Ivermectin Appearance: White Crystalline Powder
CAS No.: 70288-86-7 Molecular Formula: C48H74O14
Shelf Life: 24months When Properly Stored Purity: 99%min
HS Code: 2932999099 Function: Antiparasitic Drug
Storage Condition: Keep Away From Heat, Open Flames And Sparks.
High Light:

70288-86-7 Ivermectin Powder

,

Anti Leishmaniasis Ivermectin Powder


Product Description

Antibiotic Antiparasitic Drug Ivermectin Powder For Anti-Leishmaniasis CAS 70288-86-7

Antibiotic Antiparasitic Drug Ivermectin Powder For Anti-Leishmaniasis CAS 70288-86-7 0

Product Introduction

Ivermectin is a new type of antibiotic antiparasitic drug with broad spectrum, high efficiency and low toxicity. It has good repellent effect on both in vivo and in vitro parasites, especially nematodes and arthropods. But not to tapeworms, trematode and protozoa. Large ring lactone class parasite drug resistance to nematodes and the function of flooding killed by arthropods, is to increase the insect body inhibitory neurotransmitter gamma aminobutyric acid (GABA) release, and open the glutamic acid control Cl ion channels, strengthen the nerve membrane permeability of Cl, thereby blocking nerve signal transmission, nerve palsy, eventually lose muscle contraction ability, This causes the body to die.

 

Function:

This product is a derivative of avermectin, which is an oral semi-synthetic broad-spectrum antiparasitic drug. This product has action on most (but not all) nematodes of various life cycles; It was effective against the microfilariae of Onococca, but not against the adults. It is also effective against strongylodes faecalis, which live only in the gut. This product has a selective inhibitory effect. By binding with the high affinity of glutamate as the valve of chloride ion channel in nerve cells and muscle cells of non-spinal animals, it leads to an increase in the permeability of cell membrane to chloride ion, resulting in hyperpolarization of nerve cells or muscle cells, and paralysis or death of parasites. It may also interact with the chloride channels of other ligand valves, such as the neurotransmitter G-aminobutyric acid (GABA). The selectivity of this product is due to the absence of glutamate-chloride channels in some mammals and the low affinity of abamectin for mammalian ligand-chloride channels. This product cannot penetrate the human blood-brain barrier. Onchocerciasis and strongyloidosis and hookworm, roundworm, whipworm, pinworm infection.

 

Product analysis report

 

Product Name Ivermectin Batch No 2021041201 Quantity 750kgs
Manufacturing Time Apr.12.2021 Expiry Date Apr.12.2023 Test Date Apr,12,2021
Specification USP40
Tests Specification Results
Appearance While or yellowish-white crystalline powder Qualified

 

Solubility

Practically insoluble in water. freely soluble inmethylene

chloride, soluble in alcohol (96%)

 

Qualified

 

 

Identification

IR Corresponds with that of CRS standard Qualified
 

 

HPLC

The retention time for H2Bla and H2B1b corresponds with that of standard preparation

 

Qualified

Appearance of solution Clear and not more intensely colored than BY7 Qualified

Specific optical rotation (anhydrous and

solvent-free substance)

 

-17~-20

 

-18.2

 

 

 

 

 

Related substances (%)

Individual impurities(RRTI.3-1.5)≤2.5 l-l:<0.05; K:2.l
 

 

 

 

Any other individual impurities≤l

C:0.07 A:027 J:0.20 H:0. 16 D:0.08 F: 0.07

E:0.57 1-2:0.14

RRT 1.09:0.06

  Total≤5 3.7
  Disregard limit ≤0.05 0.05

 

Ethanol and Formamide(%)

Ethanol≤5.0 3.7
  Formamide ≤3.0 2.6
Water (%) ≤1.0 0.12
Sulphated ash (%) ≤0.1 0.08
Cat(ug/g) ≤1.0 <1
Assay(%) H2B1a(H2B1a+H2Blb)≥90.0 97.5
(HPLC. On dry basis) 95.0≤H2B1a+H2B1b≤102.0 96.1
Conclusion Conforms With USP40

 

 

Competitive Advantages

1.Golden Manufactory under ISO/GMP with large stock.
2.We offer high quality products at competitive price.
3.Shortest delivery time.
4.Flexible payment terms.
5.Timely after-sale service.
6.International Authorized Third-Party Test For The Products You Demand.
7.Our products have been exported to USA, Japan, Germany, France, United Kingdom, Italy, Brazil, Canada, Russia,Turkey,South Korea,French,Thailand,Malaysia,Spain and many other countries.

 

FAQ

1.Can I get samples for testing?

Yes,sample can be provided,but you will need to pay the freight.

 

2.What's the delivery leadtime?
3-7 days by air after payment, if it is by sea, the shipment time should be determined according to the shipping date.
 
3.Do you accept customized or OEM service?
OEM service: capsules, tablets and packaging powder for retail. Detailed package, private label is available for large order, above 10,00 Pieces/bottles.
 
4.What’s your standard & documents?
Normally, our product standard is basis on USP, EP, CP or Enterprise standard. GMP, ISO, COA, MSDS, DGM, form A and so on has been passed. We have good quality control.
 
5.Are you a manufacture?
Yes, we are manufacture, pictures, vedios, docs can be provided. Welcome to visit our factory.

Contact Details
Marshall Liu

Phone Number : +8615691930561

WhatsApp : +8618629242069