|Place of Origin:||China|
|Minimum Order Quantity:||1kg|
|Packaging Details:||1.1kg/bag;25kg/drum 2. Inside: steril plastic bag+aluminum foil bag Outside: carton/drum|
|Payment Terms:||T/T, Western Union,, L/C, D/A, D/P|
|Supply Ability:||10Metric tons per month|
|Product Name:||Ivermectin||Appearance:||White Crystalline Powder|
|CAS No.:||70288-86-7||Molecular Formula:||C48H74O14|
|Shelf Life:||24months When Properly Stored||Purity:||99%min|
|HS Code:||2932999099||Function:||Antiparasitic Drug|
|Storage Condition:||Keep Away From Heat, Open Flames And Sparks.|
70288-86-7 Ivermectin Powder,
Anti Leishmaniasis Ivermectin Powder
Antibiotic Antiparasitic Drug Ivermectin Powder For Anti-Leishmaniasis CAS 70288-86-7
Ivermectin is a new type of antibiotic antiparasitic drug with broad spectrum, high efficiency and low toxicity. It has good repellent effect on both in vivo and in vitro parasites, especially nematodes and arthropods. But not to tapeworms, trematode and protozoa. Large ring lactone class parasite drug resistance to nematodes and the function of flooding killed by arthropods, is to increase the insect body inhibitory neurotransmitter gamma aminobutyric acid (GABA) release, and open the glutamic acid control Cl ion channels, strengthen the nerve membrane permeability of Cl, thereby blocking nerve signal transmission, nerve palsy, eventually lose muscle contraction ability, This causes the body to die.
This product is a derivative of avermectin, which is an oral semi-synthetic broad-spectrum antiparasitic drug. This product has action on most (but not all) nematodes of various life cycles; It was effective against the microfilariae of Onococca, but not against the adults. It is also effective against strongylodes faecalis, which live only in the gut. This product has a selective inhibitory effect. By binding with the high affinity of glutamate as the valve of chloride ion channel in nerve cells and muscle cells of non-spinal animals, it leads to an increase in the permeability of cell membrane to chloride ion, resulting in hyperpolarization of nerve cells or muscle cells, and paralysis or death of parasites. It may also interact with the chloride channels of other ligand valves, such as the neurotransmitter G-aminobutyric acid (GABA). The selectivity of this product is due to the absence of glutamate-chloride channels in some mammals and the low affinity of abamectin for mammalian ligand-chloride channels. This product cannot penetrate the human blood-brain barrier. Onchocerciasis and strongyloidosis and hookworm, roundworm, whipworm, pinworm infection.
Product analysis report
|Product Name||Ivermectin||Batch No||2021041201||Quantity||750kgs|
|Manufacturing Time||Apr.12.2021||Expiry Date||Apr.12.2023||Test Date||Apr,12,2021|
|Appearance||While or yellowish-white crystalline powder||Qualified|
Practically insoluble in water. freely soluble inmethylene
chloride, soluble in alcohol (96%)
|IR||Corresponds with that of CRS standard||Qualified|
|The retention time for H2Bla and H2B1b corresponds with that of standard preparation||
|Appearance of solution||Clear and not more intensely colored than BY7||Qualified|
Specific optical rotation (anhydrous and
Related substances (%)
|Individual impurities(RRTI.3-1.5)≤2.5||l-l:<0.05; K:2.l|
Any other individual impurities≤l
C:0.07 A:027 J:0.20 H:0. 16 D:0.08 F: 0.07
|Disregard limit ≤0.05||0.05|
Ethanol and Formamide(%)
|Sulphated ash (%)||≤0.1||0.08|
|(HPLC. On dry basis)||95.0≤H2B1a+H2B1b≤102.0||96.1|
|Conclusion||Conforms With USP40|
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