| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO9001 |
| Model Number: | Vinpocetine |
| Minimum Order Quantity: | 10grams |
| Price: | 35USD/gram |
| Packaging Details: | 1.1kg/bag;25kg/drum 2. Inside: steril plastic bag+aluminum foil bag Outside: carton/drum |
| Delivery Time: | 3-7days |
| Payment Terms: | T/T, ,, L/C, D/A, D/P |
| Supply Ability: | 10Metric tons per month |
| Product Name: | Vinpocetine | Appearance: | White Crystalline Powder |
|---|---|---|---|
| CAS No.: | 42971-09-5 | Molecular Formula: | C22H26N2O2 |
| Shelf Life: | 24months When Properly Stored | Purity: | 99%min |
| HS Code: | 2933990090 | Function: | Peripheral Vasodilator |
| Storage Condition: | Keep Away From Heat, Open Flames And Sparks. | Whatsapp: | 86 15202961574 |
| High Light: | API Pharmaceutical 143-67-9,Pharmaceutical Grade Vincristine Sulfate,99%Min Purity Vincristine Sulfate Powder |
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Circulatory system medication Peripheral vasodilator Vinpocetine Powder CAS 42971-09-5
Vinpocetine is a semisynthetic derivative of the alkaloid vincamine, an extract from the periwinkle plant.Vinpocetine is reported to have cerebral blood-flow enhancing and neuroprotective effects, and is usedas a drug in Eastern Europe for the treatment of cerebrovascular disorders and age-related memoryimpairment.It binds tubulin, thereby inhibiting the assembly of microtubules. It is M phase cell cycle specific since microtubules are a component of the mitotic spindle and the kinetochore which are necessary for the separation of chromosomes during anaphase of mitosis. Toxicities include bone marrow suppression (which is dose-limiting), gastrointestinal toxicity, potent vesicant (blister-forming) activity, and extravasation injury (forms deep ulcers).Vinblastine paracrystals may be composed of tightly-packed unpolymerized tubulin or microtubules.
Vinpocetine is a kind of drug for improving cerebral vessels, which has the effect of expanding cerebral vessels, improving cerebral metabolism and improving cognition.
1, expansion of cerebral vessels long spring etine can expand cerebral vessels, increase blood flow to the brain, for cerebral thrombosis, cerebral infarction and other diseases have a certain therapeutic effect, but also can prevent the recurrence of cerebral infarction.
2, improve brain metabolism vinpocetine can improve brain metabolism, promote the repair and regeneration of nerve cells, for brain nerve function damage, memory loss, senile dementia and other diseases, has a certain therapeutic effect.
3, improve cognition Vinpocetine can improve cognition, improve cognitive ability, chronic brain ischemia, cerebral blood insufficiency, mild cognitive dysfunction, etc., has a certain therapeutic effect.
In addition, vinpocetine also has the effect and efficacy of inhibiting platelet aggregation. Patients need to use drugs correctly under the guidance of doctors, and can not blindly use drugs, so as not to aggravate the condition and not conducive to the recovery of the body. If discomfort occurs during the use of drugs, it is necessary to stop the drug and seek medical treatment in time.
Whatsapp:+86 15202961574
Function:
1.Vinpocetine is chemically related to, and derived from vincamine, an alkaloid found in the periwinkle plant.
2. It was introduced into clinical practice in Europe more than two decades ago for its role in cerebrovascular disorders and related symptoms.
3.Experiments with this periwinkle extract indicate that it can dilate blood vessels, cross the blood-brain barrier, enhance circulation in the brain, improve oxygen utilization, make red blood cells more pliable, and inhibit aggregation of platelets.
4.Vinpocetine even has antioxidant properties. Levels peak in the bloodstream within an hour and a half after ingestion.
Application
1.Applied in the food field, it has become a new raw material which used in food and beverage industry;
2.Applied in the health product field;
3.Applied in the pharmaceutical field.
Product analysis report
| Product Name:Vinpocetine |
| Test sample: 1gram Sample base: 5gram |
| Manufacture Date: 1st Nov,2022 Analysis Date: 1st Nov, 2022 |
| Batch NO.:HNB221101-4 |
| Storage: Store in cool & dry place, in well-closed containers. |
| Shelf life: 24 Months when properly stored. |
| ITEMS OF ANALYSIS | SPECIFICATIONS | RESULT |
| Appearance |
White crystalline or slightly crystalline powder
|
White crystalline powder |
| Solubility | Practically insoluble in water, soluble in methylene chloride, slightly soluble in anhydrousethanol | Complies |
| Identification (IR) | Same wave numbers as that of the Vinpocetine, CRS similarly prepared | Complies |
| Specific Optical Rotation (On dried basis) | Between +127°and +134° | +132.7° |
| Residue on ignition | ≤0.10% | 0.04% |
| Melting Point | 149～153℃ | 150℃ |
| Loss on drying | ≤0.5% | 0.04% |
| Sulphated ash | ≤0.1% | 0.07% |
| Related Substances | Ethyl vincaminate(A) ≤0.6% | Complies |
| Apovincamine(B) ≤0.5% | Complies | |
| Methoxyvinpocetine(C) ≤0.3% | Not detected | |
| Dihydrovinpocetine(D) ≤0.5% | Not detected | |
| Other single impurity ≤0.10% | Complies | |
| Total impurity ≤1.0% | 0.19% | |
| Heavy metals | ≤10ppm | Complies |
| Assay | 98.0~102.0% (Calculated on anhydrous basis) | 99.4% |
| Conclusion | The above material complies with USP38 | |