| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO9001 |
| Model Number: | Allopurinol |
| Minimum Order Quantity: | 25kg |
| Price: | 55USD/kg |
| Packaging Details: | 1.1kg/bag;25kg/drum 2. Inside: steril plastic bag+aluminum foil bag Outside: carton/drum |
| Delivery Time: | 3-7days |
| Payment Terms: | T/T, ,, L/C, D/A, D/P |
| Supply Ability: | 5 Metric tons per month |
| Product Name: | Allopurinol | Appearance: | White Powder |
|---|---|---|---|
| CAS No.: | 315-30-0 | Molecular Formula: | C5H4N4O |
| Shelf Life: | 24months When Properly Stored | Purity: | 99%min |
| HS Code: | 2933990099 | Function: | Antipyretic Analgesics |
| Storage Condition: | Keep Away From Heat, Open Flames And Sparks. | ||
| High Light: | Anti Gout Allopurinol Powder,CAS 315-30-0 Antipyretic Analgesic,Medical Grade Allopurinol Powder |
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Anti-Gout Medicine Allopurinol Powder CAS 315-30-0
llopurinol (Zyloprim) is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.Target: XAOAllopurinol (Zyloprim, and generics) is a drug used primarily to treat hyperuricemia (excess uric acid in blood plasma) and its complications, including chronic gout. It is a xanthine oxidase inhibitor which is administered orally. A common misconception is that allopurinol is metabolized by its target, xanthine oxidase, but this action is principally carried out by Aldehyde oxidase. The active metabolite of allopurinol is oxypurinol, which is also an inhibitor of xanthine oxidase. Allopurinol is almost completely metabolized to oxypurinol within two hours of oral administration, whereas oxypurinol is slowly excreted by the kidneys over 18–30 hours. For this reason, oxypurinol is believed responsible for the majority of allopurinol's effect.Allopurinol is a purine analog; it is a structural isomer of hypoxanthine (a naturally occurring purine in the body) and is an inhibitor of the enzyme xanthine oxidase. In addition to blocking uric acid production, inhibition of xanthine oxidase causes an increase in hypoxanthine and xanthine. While xanthine cannot be converted to purine ribotides, hypoxanthine can be salvaged to the purine ribotides adenosine and guanosine monophosphates. Increased levels of these ribotides may cause feedback inhibition of amidophosphoribosyl transferase, the first and rate-limiting enzyme of purine biosynthesis. Allopurinol, therefore, decreases uric acid formation and may also inhibit purine synthesis.
Function:
1.Primary and secondary hyperuricemia, especially hyperuricemia, is also used for renal insufficiency hyperuricemia;
2,for the treatment of gout, suitable for recurrent attacks or chronic gout. It can relieve symptoms and reduce the formation of kidney uric acid stones in gouty nephropathy patients.
3.Gouty stone;
4,for uric acid kidney stones and/or uric acid nephropathy.
Product analysis report
| Product Name | Allopurinol | ||
| Batch No.: | HNB20230218 | Manufacture Date: | Feb-18-2023 |
| Batch Size: | 25kg/fibre drum | Analysis Date: | Feb-20-2023 |
| Sample: | 50g | Expiry Date: | Feb-18-2025 |
| Storage: | Store in cool & dry place, in well-closed containers. | ||
| Shelf life: | 24 Months when properly stored. | ||
| ITEMS OF ANALYSIS | SPECIFICATIONS | RESULT | |
| Appearance | White Powder | Complies | |
| Identification | A: Chemical reaction | Complies | |
| B: Matches IR Reference standard | Complies | ||
| Assay | 94.5-97.5% | 90.1% | |
| Loss on drying | 0.50-1.50% | 0.62% | |
| Bulk density | 0.40-0.70g/ml | 0.70g/ml | |
| Sieve Analysis | Retained on 100Mesh | ≥20% | 90.54% |
| Retained on 20Mesh | ≥70% | 95.86%% | |
| Residue on ignition | ≤0.20% | <0.20% | |
| Heavy Metals | ≤0.002% | <0.002% | |
| Related Substances | Impurity J | (4-Chloroacetanilide)≤9ppm | Below LOD |
| Impurity K | (4-Aminophenol)≤45ppm | Below LOD | |
| Impurity F | (4-nitrophenol)≤0.045% | Below LOD | |
| Anyother impurity | ≤0.045% | <0.045% | |
| Total of other impurities | ≤0.09% | <0.09% | |
| Microbial Limits | Total acrobic bacteria count | NMT≤500cfu/g | <500cfu/g |
| Mold and yeast count | NMT≤50cfu/g | <50cfu/g | |
| Encherichia coli | None | None | |
| Conclusion: Conforms Standard | |||
Competitive Advantages
1.Golden Manufactory under ISO/GMP with large stock.
2.We offer high quality products at competitive price.
3.Shortest delivery time.
4.Flexible payment terms.
5.Timely after-sale service.
6.International Authorized Third-Party Test For The Products You Demand.
7.Our products have been exported to USA, Japan, Germany, France, United Kingdom, Italy, Brazil, Canada, Russia,Turkey,South Korea,French,Thailand,Malaysia,Spain and many other countries.
FAQ
1.Can I get samples for testing?
Yes,sample can be provided,but you will need to pay the freight.
