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HNB Synthetic Quinolone Pazufloxacin Mesylate CAS 163680-77-1

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Pazufloxacin mesylate
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 163680-77-1 Mf: C17H19FN2O7S
MW: 414.405 Specification: ≥98%
Einecs No.: N/A Appearance: Yellow Powder
High Light:

Synthetic Quinolone Pazufloxacin mesylate

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CAS 163680-77-1 Pazufloxacin mesylate

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CAS 163680-77-1 anti infective drugs


Product Description

CAS 163680-77-1 Synthetic anti-infective drugs Quinolone Pazufloxacin mesylate Powder

HNB Synthetic Quinolone Pazufloxacin Mesylate CAS 163680-77-1 0

Product Name

Pazufloxacin mesylate

Function

APIs

Specification

99%Tech

Chemical Name

(3S)-10-(1-Aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid methanesulfonate (1:1)

CAS No.

163680-77-1

Empirical Formula

C17H19FN2O7S

Toxicology

Dangerous decomposition products: carbon monoxide, carbon dioxide, nitrogen oxides (NOx), hydrogen fluoride, sulfur oxides

Applications

Pazufloxacin (T-3761) mesylate is a quinolone antibiotic.

Package

1kg/bag,25kg/drum

 

The Introductction of Pazufloxacin mesylate:

 

Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic.Target: AntibacterialPazufloxacin (T-3761), a new quinolone derivative, showed broad and potent antibacterial activity. T-3761 showed good efficacy in mice against systemic, pulmonary, and urinary tract infections with gram-positive and gram-negative bacteria, including quinolone-resistant Serratia marcescens and Pseudomonas aeruginosa. The in vivo activity of T-3761 was comparable to or greater than those of ofloxacin, ciprofloxacin, norfloxacin, and tosufloxacin against most infection models in mice.

 

The Application & Function of Pazufloxacin mesylate:

 

This product is suitable for the following infections caused by sensitive bacteria:
(1) Secondary infections of chronic respiratory diseases, such as chronic bronchitis, diffuse bronchiolitis, bronchiectasis, emphysema, pulmonary interstitial fibrosis, bronchial asthma, old tuberculosis, etc.; Pneumonia, lung abscess;
(2) pyelonephritis, complex cystitis, prostatitis;
(3) burn wound infection, surgical wound infection;
(4) cholecystitis, cholangitis, liver abscess;
(5) intra-abdominal abscess and peritonitis;
(6) infection of reproductive organs, such as adnexitis and endometritis; Pelvic inflammatory disease.

 

Application:

 

The activities of T-3761 were lower than those of tosufloxacin against gram-positive bacterial systemic and pulmonary infections in mice but not against infections with methicillin-resistant Staphylococcus aureus [1]. T-3761 had a broad spectrum of activity and had potent activity against gram-positive and -negative bacteria. The MICs of T-3761 against 90% of the methicillin-susceptible Staphylococcus aureus, methicillin-susceptible and -resistant Staphylococcus epidermidis, and Clostridium spp. tested were 0.39 to 6.25 micrograms/ml. The MBCs of T-3761 were either equal to or twofold greater than the MICs. The 50% inhibitory concentrations of T-3761 for DNA gyrases isolated from E. coli and P. aeruginosa were 0.88 and 1.9 micrograms/ml, respectively

 

The COA of ​Pazufloxacin mesylate

HNB Synthetic Quinolone Pazufloxacin Mesylate CAS 163680-77-1 1

 

Contact Details
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