|Place of Origin:||China|
|Minimum Order Quantity:||1KG|
|Packaging Details:||Aluminum foil bag|
|Payment Terms:||L/C, D/A, D/P, T/T, Western Union, MoneyGram|
|Melting Point:||252 ℃||Specification:||≥98%|
|Einecs No.:||200-685-8||Appearance:||White To Slightly Yellow Crystalline Powder|
CAS 68-35-9 Sulfadiazine Powder,
Sulfadiazine Powder For Meningococcal Meningitis,
Sulfadiazine common antibacterial drugs
CAS 68-35-9 Antibacterial Sulfadiazine 99% Powder
|Appearance||White to slightly yellow crystalline powder|
|Product Name||CAS No.||Product Name||CAS No.|
|Vitamin K2||11032-49-8||Vitamin D3||67-97-0|
The Introductction of Sulfadiazine :
Sulfadiazine is a sulfonamide anti-infective drug commonly used in clinical practice in my country, also known as sulfadiazine, diazine, and the molecular structure of sulfadiazine is similar to p-aminobenzoic acid (PABA), which can compete with PABA to act in bacteria Dihydrofolate synthase, which prevents PABA as a raw material from synthesizing folic acid required by bacteria, reducing the amount of metabolically active tetrahydrofolate, which is used by bacteria to synthesize purine, thymidine and deoxyribonucleic acid (DNA) essential substances, thus inhibiting the growth and reproduction of bacteria. Sulfadiazine is effective against Hemolytic Streptococcus, Staphylococcus, Meningococcus, Pneumococcus, Neisseria gonorrhoeae, Escherichia coli, Shigella, and other sensitive bacteria, as well as Chlamydia trachomatis, Actinomyces, Plasmodium, Nocardia stellaris and Toxoplasma gondii, etc. Microorganisms have inhibitory effects.
The Application & Function of Sulfadiazine :
1. For the prevention and treatment of meningococcal meningitis caused by sensitive bacteria
2. For the treatment of acute bronchitis, mild pneumonia, otitis media and skin and soft tissue infections caused by sensitive bacteria.
3. For the treatment of nocardiosis.
4. It can be used as a secondary drug for the treatment of neonatal inclusion body conjunctivitis caused by Chlamydia trachomatis.
5. It can be used as an adjuvant drug for the treatment of falciparum malaria resistant to chloroquine.
6. Toxoplasmosis caused by Toxoplasma gondii is treated in combination with pyrimethamine.
The COA of Sulfadiazine :
|CAS No.||68-35-9||Outer Packing||25kg|
|Production date||2021.6.17||Shelf life||2023.6.16|
|Items of analysis||Specification||Results|
|appearance||white or pale yellow crystalline power,and it is odorless and testeless||conform|
|solubility||it is freely slouble in pyridine,slightly soluble in acetone , very slightly soluble in ethanol, and practically insoluble in water an erher.it dissolves in dilute hydrochloric acid, sodium hydroxide TS and ammonia TS.||conform|
|identification(A)||the solution responds to Qualitative Tests for paimary aromatic amines||conform|
|identification(B)||the chloroform layer develops a pale-gree color||conform|
|identification(C)||the chloroform layer develops a gree color||conform|
|identification(D) IR||it exhibits at wave about 3440 cm-1,3360cm-1,3040cm-1,1652cm-1,1582cm-1,1494cm-1,1327cm-1,1158cm-1,797cm-1||conform|
|melting point||about 252ºC||256~228.4ºC|
|clarity and color of solution||the solution is clear and colorless to pale yellow||conform|
|acidity||a yellow color develops||conform|
|heavy metals||NMT 20ppm||conform|
|related substances||the spots other than the principal spot form the sample solution are not more intense than the spot form the standard solution.||conform|
|loss on drying||NMT 0.5%||0.09%|
|residue on ignition||NMT 0.1%||0.04%|