| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Piperaquine phosphate Powder |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually7-10days |
| Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram |
| Supply Ability: | 5000kg/Month |
| CAS: | 85547-56-4 | Mf: | C29H35Cl2N6O4P |
|---|---|---|---|
| MW: | 633.506 | Specification: | ≥98% |
| Einecs No.: | N/A | Appearance: | White To Pale Yellow |
| High Light: | Antiparasitic Antimalaria Piperaquine Phosphate,Piperaquine Phosphate CAS 85547-56-4,CAS 85547-56-4 active pharmaceutical intermediates |
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CAS 85547-56-4 Antiparasitic Raw Materials Antimalaria Piperaquine phosphate Powder
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Product Name |
Piperaquine phosphate |
|
Function |
Antimalaria |
|
Specification |
99%Tech |
|
Chemical Name |
4,4'-(Propane-1,3-diyldipiperazine-4,1-diyl)bis(7-chloroquinoline) phosphate (1:1) |
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CAS No. |
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Empirical Formula |
C29H35Cl2N6O4P |
|
Toxicology |
t 1/2 =17.8 d; AUC=33.5 mg•h/L; apparent clearance=1.55 L/h/kg; apparent volume of distribution=956 L/kg. |
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Applications |
Piperaquine is a diquinoline antimalarial drug commonly used as an antimalarial companion to artemisinin drug combination therapy (ACT). |
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Package |
1kg/bag,25kg/drum |
The Introductction of Piperaquine phosphate:
Piperaquine phosphate to chemical synthesis, its main ingredients are: piperazine hexahydrate, heated to dissolve (about 50°), in its addition such as 4.7- dichloroquinoline mixed reaction, after pickling (PH 2.5-3.5), alkaline washing (PH 9-10), water (PH 7- 8) and obtained. Light yellow powder.
The Application & Function of Piperaquine phosphate:
Antimalarial action of this product is similar to that of chloroquine. After oral absorption, stored in the liver, slowly released into the blood, has a long-term preventive effect. It is mainly used for the suppressive prevention of malaria symptoms and also for the treatment of malaria. It is also used in the prevention and treatment of silicosis.
Application:
1 For malaria treatment, the first dose is 0.5g, followed by another 0.25g to 0.5g 8 to 12 hours later, and the total dose is 0.75g to 1g.
2 Malaria prevention take 0.5g once a month before going to bed. Can even take 3 ~ 4 months, not more than 6 months.
3 the prevention and treatment of silicosis 0.5g/ time, 10 ~ 15 days to take 1 time, 1 month of 1g ~ 1.5g. The treatment dose was 0.5g to 0.75g/ time, once a week, 2g/month, half a year as a course; After an interval of 1 month, a second course of treatment can be carried out. The total course of treatment is about 3 ~ 5 years.
The COA of Piperaquine phosphate:
