| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Bifonazole |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually7-10days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram |
| Supply Ability: | 5000kg/Month |
| CAS: | 60628-96-8 | Mf: | C22H18N2 |
|---|---|---|---|
| Melting Point: | 310.4 | Specification: | ≥98% |
| Einecs No.: | 262-336-6 | Appearance: | White Crystalline Powder |
| High Light: | CAS 60628-96-8 Medicine Raw Material,Medicine Raw Material Antifungals Bifonazole,CAS 60628-96-8 antifungal powder for skin |
||
CAS 60628-96-8 Antibacterial Raw Material Antifungals Bifonazole
|
Product name |
Bifonazole |
|
CAS No. |
60628-96-8 |
|
Molecular formula |
C22H18N2 |
|
Molecular weight |
310.4 |
|
Purity |
99% |
|
Appearance |
White or almost white powder |
|
Package |
Aluminum Bag;Drums |
|
Shelf life |
2 years |
The Introductction of Bifonazole:
Bifonazole is an imidazol antifungal drug. Bifonazole is marketed by Bayer under the trade mark Canespor in ointment form.
Bifonazole has dual mode of action.It blocks transformation of 24-methylendihydrolanosterol to desmethylsterol in fungitogether with inhibition of HMG-CoA. This enables fungicidal properties against dermatophytes and distinguishes bifonazole from other antifungal drugs.Canesten bifonazole once daily cream contains the active ingredient bifonazole, which is an antifungal medicine. It is used to treat athlete's foot, which is a skin condition caused by infection with fungi.
Bifonazole kills the fungi that are causing the infection by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.
The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As bifonazole causes holes to appear in the cell membranes, essential constituents of the fungal cells can leak out. This kills the fungi and treats the infection.
The Application & Function of Bifonazole:
Bifonazole for imidazol antifungal agent, has a broad spectrum antifungal, skin fungi, yeast, mold and other fungi, such as mold with chaff scales spot, tiny rod-shaped bacilli is valid. In vitro experiments show that this medicine fungi (such as Trichophyton) effect is bactericidal, and is mainly bacteriostatic effect on yeast. Well, this drug through the infected skin, role in the rapid and long duration, maintaining more than 48 HR.
Bifonazole for acute and the chronic skin fungi disease, especially skin hair Tinea bacteria is, small spores bacteria is, Floc epidermal Tinea bacteria; yeast bacteria, as white beads bacteria and the other type of yeast; mold, as song mold due to of skin fungi disease; with chaff-like scales spot mold by caused of spotted bran rash; Rod-like Bacillus due to of Red Tinea; above fungi due to skin shallow table infection.
The COA of Bifonazole:
|
Item |
Specification |
Result |
|
Appearance |
white to off-white powder |
Complies |
|
Related substance (HPLC) |
Total impurity ≤0.5% |
0.2% |
|
Odor |
Characteristic |
Complies |
|
Assay |
99% |
99.8% |
|
Sieve analysis |
100% pass 80 mesh |
Complies |
|
Loss on Drying |
≤1.0% |
0.12% |
|
Heavy Metal |
<10ppm |
Complies |
|
As |
<0.1ppm |
0.05ppm |
|
Pb |
<0.1ppm |
0.05ppm |
|
Cd |
<0.1ppm |
0.05ppm |
|
Residual Solvents |
<100ppm |
Complies |
