| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Acarbose |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually3-5days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram，Alibaba Assurance Order |
| Supply Ability: | 5000kg/Month |
| CAS: | 56180-94-0 | Mf: | C25H43NO18 |
|---|---|---|---|
| MW: | 645.61 | Specification: | 99% |
| EINECS: | 260-030-7 | Appearance: | White Powder |
| Sample: | Available | Other Name: | Cortisol |
| High Light: | Pharmaceutical Raw Material 56180-94-0,99% Acarbose Powder,Pharmaceutical Grade Acarbose Powder |
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API Pharmaceutical Raw Material 99% Acarbose Powder CAS 56180-94-0
|
Product name |
Acarbose |
|
Appearance |
White powder |
|
CAS |
56180-94-0 |
|
MF |
C25H43NO18 |
|
Purity |
99% |
|
Storage |
Keep in cool dry place. |
The Introductction of Acarbose
Acarbose is an oral hypoglycemic drug that belongs to the class of alpha-glucosidase inhibitors. It slows down the rate of blood sugar increase by blocking the activity of alpha-glucosidase in the intestine and slowing down the digestion and absorption of starch and sucrose from food. It is primarily indicated for the treatment of type 2 diabetes.
Acarbose is usually obtained by synthesis. The specific method of preparation includes esterification reaction of glucose to acarbose, acid hydrolysis, reduction and etherification.
The following safety information is important to keep in mind when using acarbose:
1. tell your doctor about your history of allergies or other drug sensitivities before using this medication;
2. avoid drinking alcohol, which increases the risk of hypoglycemia;
3. because acarbose can affect the digestive system, it may cause gastrointestinal reactions (e.g., bloating, diarrhea, etc.), seek medical attention if you experience severe gastrointestinal reactions;
4. When using Acarbose, it is recommended that a low glycemic diet and moderate exercise be taken at the same time to improve the efficacy of the treatment.
Overall, Acarbose is a more commonly used oral hypoglycemic drug in controlling type 2 diabetes, but it is still necessary to follow doctor's instructions, control the dosage, and pay attention to individual differences and safety issues in the process of use.
The Application & Function of Acarbose
1. inhibits the digestion and absorption of sugars in the intestines, slowing the rate of blood glucose increase.
2. delaying the passage of food through the intestinal tract, making it easier for the patient to feel full, thus reducing the amount of food ingested.
3. promotes insulin secretion by improving insulin sensitivity, further reducing blood glucose levels.
4. reduces blood sugar fluctuations and maintains blood sugar stability.
Other Name of Acarbose
acarbose
Glucobay
Acarbose
Acarbose API
Acarbose Hydrate
Acarbose (Acarbosum)
AMylostatin J, Bay g 5421, alpha-GHI
(2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-
O-4,6-Dideoxy-4-[[[1S-(1α,4α,5β,6α)]-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-glucose
The COA of Acarbose
| ITEMS OF ANALYSIS | SPECIFICATIONS | RESULT |
| Appearance | White powder | Complies |
| Identification | IR: The spectra should be accord to the spectra of hydrocortisone CRS | Complies |
| HPLC: The principal peak in chromatogram obtained with the test solution should be accord to the principal peak in chromatogram obtained with reference solution. | Complies | |
| Solubility | Extremely soluble in water, soluble in methanol, almost insoluble in dichloromethane. | Complies |
| Related Substances | Max. Single impurity ≤ 0.5% | 0.15% |
| Total impurities ≤ 2.0% | 0.5% | |
| Loss on drying | ≤ 1.0% | 0.32% |
| Content (C21H30O5) | 98.0%~ 101.0% (on dry basis) | 99.3% |
| Conclusion | Complies with the USP standard | |