CAS: | 58-14-0 | Mf: | C12H13ClN4 |
---|---|---|---|
MW: | 248.711 | Specification: | ≥98% |
Appearance: | White Powder | Purity: | 99%,99%min |
Shelf Life: | 2 Years | Grade: | Medical Grade,Phamaceutical Grade,Medicine & Tech,USP BP FCC EP |
Whatsapp: | +86 15202961574 |
Antibiotic API CAS 58-14-0 pyrimethamine powder
The Introductction
Product Name: | pyrimethamine |
Synonyms: |
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine |
CAS: | 58-14-0 |
MF: | C12H13ClN4 |
MW: | 248.711 |
The Application & Function
This product can inhibit the dihydrofolate reductase of Plasmodium parasites, thus interfering with the normal folate translation of plasmodium parasites. It is effective against falciparum malaria and Plasmodium vivax in the early erythrocyte stage, and is commonly used as a etiological preventive drug. In addition, it can also inhibit the development of malaria parasites in mosquitoes, so it can block transmission. It is clinically used to prevent malaria and anti-relapse therapy during resting period.
The COA
Item | Specification | Results |
APPEARANCE | WHITE | CONFORMS |
SOLUBILITY | FREELY SOLUBLE IN CHLOROFORM;SOLUBLE IN WATER OR METHANOL;INSOLUBLE IN ETH | CONFORMS |
PH | 5.0-7.2 | 6.51 |
LOSS ON DRYING | ≤4.5% | 3.10% |
RESIDUEON IGNITION | ≤2.5% | 0.281% |
HEAVY METALS | ≤20PPM | <15PPM |
TYRAMINE | ≤0.35% | 0.051% |
RELATED COMPOSITIONS | TYLOSIN A ≥80% A+B+C+D ≥95% | 93% 98% |
Conclusion | Confirm with the standard |