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CAS 58-14-0 pyrimethamine powder Antibiotic API powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: HNB-pyrimethamine
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 58-14-0 Mf: C12H13ClN4
MW: 248.711 Specification: ≥98%
Appearance: White Powder Purity: 99%,99%min
Shelf Life: 2 Years Grade: Medical Grade,Phamaceutical Grade,Medicine & Tech,USP BP FCC EP

Product Description

CAS 58-14-0 pyrimethamine powder Antibiotic API powder

 

 

The Introductction

 

Pyrimethamine(RP4753) interferes with tetrahydrofolate synthesis by inhibiting dihydrofolate reductase (DHFR), which can act on protozoan infection.
Pyrimethamine, an organic compound with the chemical formula C12H13ClN4, is mainly used as an antimalarial drug for the prevention of malaria and anti-relapse treatment during the rest period.
 
Product Name: pyrimethamine
Synonyms:

5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine

CAS: 58-14-0
MF: C12H13ClN4
MW: 248.711

 

CAS 58-14-0 pyrimethamine powder Antibiotic API powder 0

 

The Application & Function

 

This product can inhibit the dihydrofolate reductase of Plasmodium parasites, thus interfering with the normal folate translation of plasmodium parasites. It is effective against falciparum malaria and Plasmodium vivax in the early erythrocyte stage, and is commonly used as a etiological preventive drug. In addition, it can also inhibit the development of malaria parasites in mosquitoes, so it can block transmission. It is clinically used to prevent malaria and anti-relapse therapy during resting period.

 

The COA

 

Item Specification Results
APPEARANCE WHITE CONFORMS
SOLUBILITY FREELY SOLUBLE IN CHLOROFORM;SOLUBLE IN WATER OR METHANOL; CONFORMS
PH 5.0-7.2 6.51
LOSS ON DRYING ≤4.5% 3.10%
RESIDUEON IGNITION ≤2.5% 0.281%
HEAVY METALS ≤20PPM <15PPM
TYRAMINE ≤0.35% 0.051%
RELATED COMPOSITIONS TYLOSIN A ≥80% A+B+C+D ≥95% 93% 98%
Conclusion Confirm with the standard  

 

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