CAS: | 22916-47-8 | Mf: | C18H14Cl4N2O |
---|---|---|---|
MW: | 416.129 | Specification: | ≥98% |
Appearance: | White Powder | Purity: | 99%,99%min |
Shelf Life: | 2 Years | Grade: | Medical Grade,Phamaceutical Grade,Medicine & Tech,USP BP FCC EP |
CAS 22916-47-8 Miconazole powder for antifungal use
The Introductction
Product Name: | Miconazole |
Synonyms: |
1-[2,4-Dichloro-b-[(2,4-dichlorobenzyl)oxy]phenethyl]imidazole |
CAS: | 22916-47-8 |
MF: | C18H14Cl4N2O |
MW: | 416.129 |
The Application & Function
Miconazole is a highly effective, safe, broad-spectrum antifungal drug, which has an effect on almost all pathogenic fungi. Its mechanism is to inhibit the sterol synthesis of fungal cell membrane, affect the membrane permeability, inhibit fungal growth, and lead to death. The concentration below 4 µg/mL can inhibit most clinically isolated fungi, among which Cryptococcus neoforme, candida and pachyspora are sensitive to this product, Blastomyces dermatitis and histoplasmosis are highly sensitive to this product, but aspergillus is less sensitive. In addition, miconazole also has antibacterial effects on Staphylococcus aureus and streptococcus, gram-positive coccus and anthrax. For skin fungal infections, such as hand, foot, body, and jock itch.
indication
Dermatophyton, yeast candida, etc. caused by the skin. Nail infection, such as tinea capitis, tinea hand, tinea foot, tinea corporis, tinea femoris, tinea versicolor, paronychitis; Vaginal or peni glans fungal infection; Ocular aspergillus or other fungal infection. The cream is widely used to treat vaginal fungal infections, such as candida vaginitis, with a cure rate of about 90%, and can still be effective after switching to patients who have used one or more other antifungal ineffective, and the treatment time is also shorter. Topical application of the product is equally effective against erosion or smooth skin fungal infections. The diluted solution (0.2% ~ 0.5%) of this product can be safely used for bladder, trachea and wound fungal flushing.
The COA
Item | Specification | Results |
APPEARANCE | WHITE | CONFORMS |
SOLUBILITY | FREELY SOLUBLE IN CHLOROFORM;SOLUBLE IN WATER OR METHANOL; | CONFORMS |
PH | 5.0-7.2 | 6.51 |
LOSS ON DRYING | ≤4.5% | 3.10% |
RESIDUEON IGNITION | ≤2.5% | 0.281% |
HEAVY METALS | ≤20PPM | <15PPM |
TYRAMINE | ≤0.35% | 0.051% |
RELATED COMPOSITIONS | TYLOSIN A ≥80% A+B+C+D ≥95% | 93% 98% |
Conclusion | Confirm with the standard |