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CAS 50-23-7 Pharmaceutical API Hydrocortisone Powder Hormone

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: HNB-Hydrocortisone
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 50-23-7 Mf: C21H30O5
MW: 362.460 Specification: ≥98%
Appearance: White Powder Purity: 99%,99%min
Shelf Life: 2 Years Grade: Medical Grade,Phamaceutical Grade,Medicine & Tech,USP BP FCC EP
High Light:

CAS 50-23-7 Pharmaceutical API

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Pharmaceutical Grade Hydrocortisone Powder

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Steroid Hormone Hydrocortisone Powder


Product Description

CAS 50-23-7 Pharmaceutical API Hydrocortisone powder hormone

CAS 50-23-7 Pharmaceutical API Hydrocortisone Powder Hormone 0

Product Name: Hydrocortisone
Synonyms:

17a-Hydroxycorticosterone

CAS: 50-23-7
MF: C21H30O5
MW: 362.460

The Introductction

Hydrocortisone is a hormone or glucocorticoid secreted by the adrenal cortex.
Hydrocortisone, also known as cortisol, is an organic compound with the chemical formula C21H30O5. It is extracted from the adrenal cortex and has the strongest effect on carbohydrate metabolism. It is a kind of glucocorticoid.
 

The Application & Function

 

Hydrocortisone is mainly used for diseases caused by adrenal insufficiency, rheumatoid arthritis, rheumatic fever, gout, bronchial asthma, and can also be used for atopic dermatitis, seborrheic dermatitis, pruritus and so on.

1. Alternative therapy should be performed after acute and chronic adrenocortical hypofunction (including adrenal crisis), adenohypopituitarism and subtotal adrenal resection.

 
2, severe infection with toxemia: such as toxic pneumonia, toxic dysentery, fulminant meningococcal meningococcal meningitis (epidemic cerebrospinal meningitis), fulminant hepatitis, severe typhoid fever, acute miliary tuberculosis, scarlet fever, sepsis, etc. Hydrocortisone can be used as adjuvant therapy while effective antibiotics are used to control infection.
 
3, allergic diseases: such as bronchial asthma, asthma status, serum disease, angioneurotic edema and other symptoms can be relieved by hydrocortisone.
 
4, anti-shock treatment: toxic shock infection, in the application of antibiotics at the same time, can be early, short time, large dose of hydrocortisone surprise use, after the effect can be stopped. For anaphylactic shock, it can be combined with epinephrine, the drug of choice. In hypovolemic shock, fluid replacement, electrolyte supplementation or blood transfusion should be used first, and hydrocortisone can be used in combination if the efficacy is poor.
 
5, prevent the sequelae of some inflammation: such as tuberculous meningitis, pleuritis, pericarditis, rheumatic valvulitis, iritis, keratitis, retinitis, optic neuritis, burn, etc., early application can prevent the occurrence of sequelae.
 
6. Others: hydrocortisone can be used in thyroid crisis, acute rejection after organ transplantation, severe pemphigus, erythroderma (exfoliative dermatitis), etc. For arthritis, tenosynovitis, tendon strain can be intrathecal injection or joint cavity injection. For contact dermatitis, eczema, psoriasis (psoriasis) can be used locally.
 

7, antitoxin effect: improve the body's tolerance to bacterial endotoxin, moderate the body's response to endotoxin, reduce cell damage, relieve toxemia. And can inhibit hypothalamus response to pyrogen, inhibit the generation and release of leukocyte pyrogen, reduce the thermoregulatory center to pyrogen sensitivity.

 

8, anti-shock effect: can inhibit the vasoconstrictive effect of vasoconstricting active substances, relieve arteriolar spasm, stabilize lysosome membrane, reduce the formation of myocardial inhibitory factors. It can prevent the release of proteolytic enzymes and the weakening of myocardial contraction caused by myocardial inhibitory factors, prevent the circulation disorders such as reduced cardiac output and systole of visceral vessels, and improve microcirculation, which has an adverse effect on toxic shock, hypovolemic shock and cardiogenic shock.

 
9, the role of the digestive system: can stimulate the secretion function of the digestive gland, promote the secretion of gastric acid and pepsin, can improve appetite, promote digestion.
 
10, reduce the pathological hyperplasia of connective tissue. For contact dermatitis, seborrheic dermatitis, neurodermatitis, pruritus and smaller areas of psoriasis.
 
11. Hydrocortisone suspension of 2.5% hydrocortisone acetate was used for intradermal injection, 0.5 ~ 1mL each time, mixed with 0.5% ~ 1% procaine 2 ~ 5mL.
 

12, 1% hydrocortisone ointment hydrocortisone acetate for dermatitis eczema, dermatitis membrane for neurodermatitis. Topical for ophthalmology and skin allergic diseases.

 

The COA

 

Item Specification Results
APPEARANCE WHITE CONFORMS
SOLUBILITY FREELY SOLUBLE IN CHLOROFORM;SOLUBLE IN WATER OR METHANOL; CONFORMS
PH 5.0-7.2 6.51
LOSS ON DRYING ≤4.5% 3.10%
RESIDUEON IGNITION ≤2.5% 0.281%
HEAVY METALS ≤20PPM <15PPM
TYRAMINE ≤0.35% 0.051%
RELATED COMPOSITIONS TYLOSIN A ≥80% A+B+C+D ≥95% 93% 98%
Conclusion Confirm with the standard  

 

CAS 50-23-7 Pharmaceutical API Hydrocortisone Powder Hormone 1CAS 50-23-7 Pharmaceutical API Hydrocortisone Powder Hormone 2CAS 50-23-7 Pharmaceutical API Hydrocortisone Powder Hormone 3CAS 50-23-7 Pharmaceutical API Hydrocortisone Powder Hormone 4

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