| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | 58001-44-8 |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually3-5days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram，Alibaba Assurance Order |
| Supply Ability: | 5000kg/Month |
| CAS: | 58001-44-8 | Mf: | C8H9NO5 |
|---|---|---|---|
| MW: | 199.16 | Specification: | 99% |
| Flash Point: | 169 To 171 ℃ | Appearance: | White Powder |
| EINECS: | 261-069-2 | Sample: | Available |
| Whatsapp: | +86 15202961574 | ||
| High Light: | Amoxycillin Clavulanic Acid Powder,Antibiotic API 58001-44-8,Antibiotic Amoxycillin Clavulanic Acid |
||
Antibiotic API CAS 58001-44-8 Amoxycillin Clavulanic Acid powder
|
Product name |
Clavulanic acid |
|
Appearance |
White Powder |
|
CAS |
58001-44-8 |
|
MF |
C8H9NO5 |
|
Purity |
99% |
|
Storage |
Keep in cool dry place. |
The Introductction of Clavulanic acid Powder
Clavulanic acid is a mold product with only weak intrinsic antibacterial activity, but it is an excellent irreversible inhibitor of most β-lactamases. It is believed to acylate the active site serine by mimicking the normal substrate. Hydrolysis occurs with some β-lactamases, but in many cases, subsequent reactions occur that inhibit the enzyme irreversibly. This leads to its classification as a mechanism-based inhibitor (or so-called suicide substrate). The precise chemistry is not well understood, but when clavulanic acid is added to ampicillin and amoxicillin preparations, the potency against β-lactamase-producing strains is markedly enhanced.
Clavulanic acid belongs to irreversible competitive type β-- The lactamase inhibitor can inactivate the enzyme after it is firmly combined with the enzyme, so it has a strong effect, not only on Staphylococcus aureus β-- Lactamase β— Lactamases also have a role. When combined with penicillin and cephalosporins, the antibacterial activity is greatly improved, the minimum inhibitory concentration (MIC) can be significantly reduced, and the drug can increase the efficacy several times to more than ten times, so that the drug resistant strains can recover their sensitivity. This product, also known as clavulanic acid, is a new oxygen-containing mother nucleus produced by Streptomyces β— Lactam antibiotics. Potassium clavulanate is acicular crystal and soluble in water
The Application & Function of Clavulanic acid Powder
Clavulanic acid is a broad-spectrum inhibitor produced by gram-positive bacteria (such as Staphylococcus aureus) β— Lactamase and type I, II, IV and V produced by gram-negative bacteria β— The lactamase has a strong inhibitory effect
Whatsapp:+86 15202961574 Mail: gary@xahnb.com
The COA of Clavulanic acid Powder
| ITEMS OF ANALYSIS |
SPECIFICATION
|
RESULT |
| Characteristics | White crystalline powder, odorless or practically odorless and practically tasteless | Complies |
| Identification | IR: The infrared absorption spectrum should be concordant with the reference spectrum | Complies |
| Solubility | Soluble in ethanol, chloroform and ane, almost insoluble in water. | Complies |
|
Water
|
≤0.5% | 0.1% |
|
ash content
|
≤0.5% | 0.2% |
|
Assay
|
99% | 99.80% |
|
Conclusion
|
Conform with the standard |
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HNB Biotech company details
