| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Doxylamine succinate |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually3-5days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram，Alibaba Assurance Order |
| Supply Ability: | 5000kg/Month |
| CAS: | 562-10-7 | Mf: | C21H28N2O5 |
|---|---|---|---|
| MW: | 388.46 | Specification: | 99% |
| Melting Point: | 103 - 108ºC | Appearance: | White Crystalline Powder |
| Sample: | Available | ||
| High Light: | API Active Pharmaceutical Ingredient,Human API Pharma Ingredients |
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CAS 6700-34-1 Pharmaceutical API Diclegis Raw Material 99% Doxylamine succinate Powder
|
Product name |
Doxylamine succinate |
|
Appearance |
White crystalline powder |
|
CAS |
562-10-7 |
|
MF |
C21H28N2O5 |
|
Purity |
99% |
|
Storage |
Keep in cool dry place. |
The Introduction of Doxylamine succinate
Doxylamine is an ethanolamine antihistamine, it is usually an over-the-counter (OTC) medication used to treat allergy and cold symptoms.
Doxylamine succinate is commonly used to relieve the symptoms of allergies, hay fever and the common cold. This medication works by blocking certain natural substances (histamine, acetylcholine) produced by the body. This effect helps relieve allergy/cold symptoms such as tearing, runny nose and sneezing.
The Application & function of Doxylamine succinate
Doxylamine succinate tablets are used clinically for the treatment of various allergic skin diseases, hay fever, allergic rhinitis, asthmatic bronchitis, and as a hypnotic for the short-term treatment of insomnia. The harmful effects of doxylamine succinate tablets are often manifested as a sedative effect on the nervous system.
A small number of patients may experience drowsiness after using doxylamine succinate tablets in clinical practice. In addition, some patients may develop hypersensitivity reactions to doxylamine succinate tablets and the ingredients in the formulation, which may manifest as skin rashes and itching and may be life-threatening. In men with lower urinary tract symptoms or benign prostatic hyperplasia, treatment with doxylamine succinate tablets may result in decreased urine flow or urinary retention due to the sedative effect on the nervous system. Female patients with stenosing peptic ulcers and pyloroduodenal obstruction may experience significant worsening of existing symptoms when treated with doxylamine succinate tablets. In addition, the drug may also induce asthma and may increase the symptoms of bladder neck obstruction. Therefore, it needs to be applied with caution in clinical practice.
Other Name of Doxylamine succinate
alsadorm
decapryn
doxylamine succinate
DOXYLAMINE SUCCINATE
LABOTEST-BB LT00244822
DOXYLAMINE SUCCINATE SALT
doxylamine hydrogen succinate
2-dimethylaminoethoxyphenylmethyl-2-picolinesuccinate
N,N-dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine
2-(alpha-(2-dimethylaminoethoxy)-alpha-methylbenzyl)pyridinesuccinate
2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-pyridinsuccinate
The COA of Doxylamine succinate
Product Name: Doxylamine succinate
Batch No.: HNB20220210
Batch Size: 150 KG
Manufacture Date: Feb., 10th, 2022 Analysis Date: Feb., 11th,, 2022 Expiry date: Feb., 09th, 2024
Storage: Well sealed in cool and dry place
Shelf life: 24 Months when properly stored.
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ITEMS |
SPECIFICATIONS |
RESULT |
|
Appearance |
White or off-white powder |
Off-white powder |
|
Identification |
(1)Positive color reaction |
Complies |
|
(2)UV |
Complies |
|
|
(3)IR |
Complies |
|
| Melting point |
103.0-108.0 ℃ |
106.5℃ |
|
Solubility |
very soluble in water,freely soluble in alcohol |
Complies |
| UVmax | 262.0nm | Complies |
|
Loss on drying |
≤ 0.5% |
0.36% |
|
Residue on Ignition |
≤ 0.1% |
0.07% |
|
Related Substances |
Impurity A≤0.5%;Impurity B≤0.5%; Impurity C≤0.5%;Impurity E≤0.5% Impurity G≤0.5% |
Complies |
|
Single impurity ≤1% |
0.01% |
|
|
Total impurities ≤2% |
0.015% |
|
|
|
Diethyl ethe*≤0.5% |
Not Detected |
|
Aceton* ≤ 0.5% |
Not Detected |
|
|
Iso-propyl ethe* ≤ 0.5% |
Not Detected |
|
|
Toluene ≤ 0.089% |
0.006% |
|
|
Conclusion |
This product complies with USP Standard |
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