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CAS 130-95-0 Pharmaceutical API Raw Material 99% Quinine Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Quinine
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 130-95-0 Mf: C20H24N2O2
MW: 324.42 Specification: 99%
EINECS No.: 205-003-2 Appearance: White Crystalline Powder
Sample: Available
High Light:

130-95-0 Pharmaceutical API

,

99% Quinine Powder

,

Quinine API Raw Material


Product Description

CAS 130-95-0 Pharmaceutical API Raw Material 99% Quinine Powder

CAS 130-95-0 Pharmaceutical API Raw Material 99% Quinine Powder 0

Product name

Quinine

Appearance

White crystalline powder

CAS

130-95-0

MF

C8H11NO3

Purity

99%

Storage

Keep in cool dry place.

CAS 130-95-0 Pharmaceutical API Raw Material 99% Quinine Powder 1

 

The Introductction of Quinine

Quinine, also known as cinchona cream and cinchona base, is the main alkaloid in the bark of the cinchona tree and its congeners of the Rubiaceae family.


Quinine chemically belongs to the quinoline class, and isomeric with quinidine. It is a white amorphous powder or crystalline, odorless, with a very bitter taste. Melting point 172.8°C, with levophoricity, [α]D20-168° (ethanol). Soluble in ethanol, chloroform, benzene, ethe*, slightly soluble in water. Its dilute sulfuric acid solution has blue fluorescence, add bromine water and excess ammonia drop by drop, it will show emerald green.


Quinine is one of the oldest antimalarial drugs. As early as the 15th century, cinchona bark containing quinine has been widely used as a potent drug for malaria treatment, and its antimalarial effect is similar to that of chloroquine, which works by interfering with DNA synthesis.

 

The Application & function of Quinine

Quinine is used clinically in patients with Plasmodium vivax infection resistant to chloroquine. It is also used for Plasmodium interna and Plasmodium falciparum. All medical uses are salts of quinine. The sulfate is for oral administration and the hydrochloride is for injection.


Quinine inhibits the intraerythrocytic phase of various Plasmodium species and controls the onset of malaria symptoms. It also has some effect on the gametophytes of Plasmodium interna and Plasmodium tris. However, it has no effect on the extra-erythrocytic stage.


In addition to medicinal use, quinine can be used in analytical chemistry as a detecting agent for metal ions such as bismuth and platinum, and as a precipitant for racemic organic acids.

 

 

Other Name of Quinine

 

Quinine
Quinine free base
Quinine anhydrous
(8R,9S)-Quinidine-d3
(-)-QUININE FOR RESOLUTION OF RACEMATES

 

 

The COA of Quinine

 

Batch No.: HNB221124
Product Name: Quinine
CAS No.: 550-99-2
Manufacture Date: Nov.12th,2022                    Expiry Date: Nov.11th,2024
Sample Date: Nov.13h,2022                            Analysis Date: Nov.12th,2022
Storage: Store in cool&dry place, in well-closed containers.
Shelf life: 24 Months when properly stored.
Reference standard: USP38
 
I
Items Specified Results

 

Appearance

White Crystalline Powder,soluble in water, almost insoluble in alcohol, chloroform and

diethyl ethe*

 

White Crystalline Powder

 

 

 

ID

Maximum UV absorption

Maximum UV absorption wavelength is at

257nm,329nm and 343nm respectively.

Conforms
  IR Conform to reference substance Conforms
  Sulpahte identification Positive Positive
Loss on Drying ≤2.0% 0.13%
pH 3.5—4.5 4.2
Mesh size 80mesh Conforms
Ordinary Impurities ≤1.0% Conforms
Methylene dichloride ≤0.06% 0.004%
Ethnol ≤0.5% 0.4%
Assay(on dried basis) 98.0% - 102.0% 99.3%
Bacteria ≤1000 cfu/g 10 cfu/g
Mold and Yeast ≤100cfu/g ≤10 cfu/g
E.coli Absent Absent
Live mite Absent Absent

Packing & Storage

Packed in paper-drums and two plastic-bags inside.

Net weight:25kg.

Shelf Life Two years if sealed and store away from direct sun light.
Conclusion Conforms With USP 38

Contact Details
Beryl Jia

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