| Place of Origin: | China |
|---|---|
| Brand Name: | BCB |
| Certification: | ISO |
| Model Number: | Indometacin |
| Minimum Order Quantity: | 1 |
| Price: | 100 |
| Packaging Details: | 1kg/bag, 25kg/drum |
| Delivery Time: | 7 working days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram |
| Supply Ability: | 10000kg/month |
| Purity: | 98% | Appearance: | White To Off-white Powder |
|---|---|---|---|
| MF: | C19H16ClNO4 | MW: | 357.79 |
| CAS No.: | 53-86-1 | EINECS: | 200-186-5 |
| High Light: | Anti Inflammatory Raw Material Indomethacin Powder,Indomethacin Powder CAS 53-86-1 |
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Anti-Inflammatory Raw Material Indometacin Powder CAS 53-86-1
| Prodcut name | Indomethacin |
| MOQ | 1kg |
| Specification | 99% |
| Appearance | White powder |
| CAS No. | 53-86-1 |
| MF | C19H16ClNO4 |
The introduction of Indometacin Powder :
Indometacin belongs to BCS class drugs, high permeability, low solubility, poor dissolution, low bioavailability in vivo. Indomethoxacin is a non-steroidal anti-inflammatory drug (NSAIDs), which has anti-inflammatory, antipyretic and analgesic effects. It plays an anti-inflammatory role by inhibiting cyclooxygenase and reducing prostaglandin synthesis, while the antipyretic effect is related to inhibiting prostaglandin synthesis in the hypothalamus.
The Application & Function of Indometacin Powder :
1.Indometacin or indomethacin is a non-steroidal anti-inflammatory drug (NSAID), to reduce fever, pain, stiffness, and swelling.
2.Indomethacin is commonly used as a prescription medication to treat fever, analgesic or inflammation caused by many conditions such as arthritis, gout, ankylosing spondylitis, bursitis, rheumatism, or tendinitis.
3.Indometacin works by reducing the production of prostaglandins, Prostaglandins are chemicals that the body produces and which cause the fever and pain that are associated with inflammation. Indometacin is similar to ibuprofen (Motrin) and naproxen (Naprosyn, Aleve).
The COA of Indometacin Powder :
| Items | Standards | Results | |
| Appearance | White or off-white solid powder | Complies | |
| Identification | By IR | Complies | |
| By HPLC | Complies | ||
| Solubility | Soluble in DMF, sparingly soluble in THF, slightly soluble in meth-anol and acet-onitrile, very sightly soluble in ethanol and dichloro-methane, insoluble in water | Complies | |
| Polymorphic Form | Polymorphic form 1 | Complies | |
| Melting Point | 211ºC~216ºC | 212.8ºC~214.9ºC | |
| Water Content | ≤ 0.50% | 0.10% | |
| Heavy Metals | ≤ 20ppm | Complies | |
| Residue on Ignition | ≤ 0.20% | 0.09% | |
| Related Substance | Any single impurity: ≤0.10% | 0.06% | |
| Total Impurities: ≤1.00% | 0.16% | ||
| Assay (on the anhydrous basis) | 98.0%~102.0% | 99.94% | |
| Particle Size | D90: ≤100µm | Complies | |
| Reference Standard | In-house Standard | ||
| Conclusion | The product complied to In-house standard. | ||
| Storage | Preserve in tight,light-resistant containers in a cool place | ||