|Place of Origin:||China|
|Model Number:||Benzocaine hydrochloride|
|Minimum Order Quantity:||1KG|
|Packaging Details:||Aluminum foil bag|
|Payment Terms:||L/C, D/A, D/P, T/T, Western Union, MoneyGram，Alibaba Assurance Order|
|Einecs No.:||N/A||Appearance:||White Crystalline Powder|
|Sample:||Available||Whatsapp:||+86152 029 61574|
|Other Names:||3 5-Diiodo-L-thyronine|
Anesthetic Lidocaine Benzocaine,
API Hydrochloride Lidocaine 99%
Antipyretic Analgesic Lidocaine Benzocaine Hydrochloride Procaine HCL
The Introductction of Benzocaine hydrochloride(Benzocaine HCl)
Benzocaine hydrochloride, also known as ethyl para-aminobenzoate, is a fat-soluble surface anesthetic, colorless rhomboidal crystals, odorless and tasteless. Soluble in alcohol, ether, chloroform, soluble in almond oil, olive oil, dilute acid, insoluble in water. It is used clinically for analgesia and antipruritic of trauma, ulcer surface, burns, skin abrasion and hemorrhoids.
Compared with several other local anesthetics such as lidocaine and dicaine, Benzocaine has less strength of action and thus does not cause discomfort due to anesthetic effect when acting on mucous membranes. It is a fat-soluble drug, so it is easy to combine with the lipid layer of mucous membrane or skin, but it is not easy to penetrate into the body and produce toxicity.
Benzocaine, as a non-water-soluble local anesthetic, has the effect of pain relief and itching, and is clinically used for trauma anesthesia, ulcer surface anesthesia, mucosal surface anesthesia and hemorrhoid anesthesia, whose pharmacological effect is mainly to block nerve endings to relieve pain and itching.
The local anesthetic effect of benzocaine is weaker than that of procaine, which cannot be used for infiltration and has a slow and long-lasting local absorption. It is hydrolyzed to para-aminobenzoic acid, which has no irritation and toxicity at a normal use concentration of 2% to 10%, and its toxicity is only equivalent to 5% of cocaine or 1Chemicalbook 0%, and the maximum safe amount for local use is 5g or 20% solution 25mL. It inhibits the conduction of nerve impulses from sensory nerve endings and dulls the sense of taste, and its structure is similar to that of procaine, so it is absorbed slowly and has a long-lasting anesthetic effect. The structure is similar to that of procaine, so it is absorbed slowly and the anesthetic effect is long lasting.
Benzocaine can cause allergic reactions. The positive reaction rate of benzocaine patch test in patients is 3.3% to 5.9%. Occasionally, dizziness, nausea, local or systemic allergic reactions such as rash, urticaria, and edema are seen.
Benzocaine HCl can be used as a precursor raw material for oxytocin, oxycaine, procaine, etc..
Benzocaine HCl is also used as a local anesthetic in medicine, with pain and itching relief, mainly for trauma, ulcer surface, mucosal surface and hemorrhoids anesthesia pain and itching relief, its ointment can also be used as a lubricating pain relief for nasopharyngeal catheter, endoproctoscope, etc.
Benzocaine HCL temporarily relieves the discomfort of painful and itchy skin, mild burns, sunburn, wounds and insect bites.
Benzocaine HCL ear preparations are used to relieve pain and itching in acute congestive and concentrated otitis externa, swimmer's ear, and for external use in the ear.
Benzocaine HCl is also effective for toothache, sore throat, mouth ulcers, various types of hemorrhoids, anal fissures, and vulvar itching.
Benzocaine HCl is used as a male genital desensitizer to slow ejaculation.
Benzocaine HCl is also used as an anesthetic lubricant for catheters and endoscopic tubes.
|Product||Benzocaine hydrochloride(CHClNO||batch No.||21012604|
|Mfg. date||2021.01.26||Expiry date||2023.01.25|
|Character||White or light yellow crystalline powder, and specific odor||White crystalline powder|
|Insoluble in water,very easily soluble in ethanol(96%)and chloroform,||Conforms|
|Identification||(1) IR conform with reference substance||Conforms|
|(2) the main peak retention time conform with the reference substance||Conforms|
|Residue on ignition||≤0.1%||0.05%|
|Assay||(CHClNO content should between 97.5%～102.5%||99.87%|
|Conclusion: conform with USP40|