Place of Origin: | China |
---|---|
Brand Name: | HNB |
Certification: | ISO |
Model Number: | Oxytetracycline hydrochloride |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually7-10days |
Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram |
Supply Ability: | 5000kg/Month |
CAS: | 2058-46-0 | Mf: | C22H25ClN2O9 |
---|---|---|---|
MW: | 496.89 | Specification: | 98% |
Einecs No.: | 218-161-2 | Appearance: | Yellow Crystalline Powder |
CAS 2058-46-0 Veterinary Antibiotic API Oxytetracycline hydrochloride
Product Name |
oxytetracycline hcl |
CAS No. |
2058-46-0 |
Appearance |
Yellow crystalline powder |
Molecular Formula |
C12H14Cl2FNO4S |
Heavy metal: |
≤0.005% |
Purity |
96.2% |
PH |
2.5 |
Water |
0.67% |
Standard: |
USP31 EP5.0, BP |
The Introductction of Oxytetracycline hydrochloride:
Oxytetracycline hydrochloride, antibiotics. Alias: Methomycin, oxytetracycline. Oxytetracycline hydrochloride is a broad-spectrum bacteriostatic agent, many Rickettsia, Mycoplasma genus, chlamydia, spirochetes, amoeba protozoa and some malaria parasites are also sensitive to this product. Enterococcus is resistant to it. Other such as actinomycetes,Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, Yersinia are sensitive.
The Application & Function of Oxytetracycline hydrochloride:
Oxytetracycline HCl belongs to the tetracyclines class of drugs. The medication is effective against a wide range of bacteria including those infecting the eyes, bones, sinuses, respiratory tract and blood cells. It works by interfering with the production of proteins that the bacteria need to multiply and divide, thus hampering the spread of the infection. Besides being used for preventing bacterial growth in cats and dogs, Oxytetracycline HCl is effective for the treatment of bacterial enteritis and bacterial pneumonia in pigs, cows, sheep, chicken, turkey, and even honey bees.
Oxytetracycline hydrochloride can be used as a drug for the following diseases:
(1) Rickettsia disease, including epidemic typhus, endemic typhus, rocky mountain fever, tsutsugamushi disease and Q fever.
(2) Mycoplasma infection.
(3) Chlamydia infection, including parrot fever, sexually transmitted diseases, lymphoid edema, nonspecific urethritis, salpingitis, cervicitis and trachoma.
(4) return to heat.
(5) brucellosis.
(6) Cholera.
(7) Rabbit fever.
(8) Plague.
(9) chancre.
Treatment of brucellosis and plague when combined with aminoglycosides.
As the current common pathogens resistant to oxytetracycline hydrochloride serious, only in the pathogen sensitive to the goods, can be used as a drug: the sensitive strains of Escherichia coli, Enterobacter aeruginosa, , Shigella, Haemophilus influenzae (respiratory tract infection only) and Klebsiella (limited to respiratory and urinary tract infections) and other Gram-negative bacilli infection.
Oxytetracycline hydrochloride should not be used for any type of staphylococcus or hemolytic streptococcal infection.
Oxytetracycline hydrochloride can be used for penicillin allergy to tetanus, gas gangrene, yas, syphilis, gonorrhea and leptospirosis as well as actinomycetes, Listeria infection in patients.
Oxytetracycline hydrochloride can be used for acute intestinal amebiasis and moderate to severe acne patients as adjuvant therapy.
The COA of Oxytetracycline hydrochloride:
Items |
Specifications |
Results |
|
Characters |
Yellow, Crystalline Powder |
Conform |
|
Solubility |
Freely soluble in water, Sparingly soluble in alcohol |
Conform |
|
Identification |
A: Thin-layer chromatography results |
Conforms |
|
B: Colour reaction with sulfuric acid |
Conforms |
||
C: Give reaction (a) of chlorides |
Conforms |
||
pH |
2.3~2.9 |
2.5 |
|
Specific optical rotation |
-188~-200 |
-196 |
|
Specific absorbance |
270~290 |
283 |
|
Light |
430nm |
≤0.50 |
0.18 |
490nm |
≤0.20 |
0.04 |
|
Related substances (%) |
Impurity A |
≤0.5 |
0.26 |
Impurity B |
≤2.0 |
0.47 |
|
Impurity C |
≤2.0 |
1.7 |
|
Total of impurities D. E and F |
≤2.0 |
0.2 |
|
Disregard limit |
≤0.1 |
conform |
|
Heavy metals (ppm) |
≤50 |
<50 |
|
Water(%) |
≤2.0 |
1.2 |
|
Sulfated ash(%) |
≤0.5 |
0.24 |
|
Assay (%) |
95.0~102.0 |
98.3 |
|
(ppm) |
≤3000 |
632 |
|
Conclusion |
The results can conforms with BP2018/EP9 |