|Place of Origin:||China|
|Model Number:||Prostaglandin E1|
|Minimum Order Quantity:||1G|
|Packaging Details:||Aluminum foil bag|
|Payment Terms:||L/C, D/A, D/P, T/T, Western Union, MoneyGram，Alibaba Assurance Order|
|Einecs No.:||212-017-2||Appearance:||White Crystalline Powder|
|Sample:||Available||Whatsapp:||+86152 029 61574|
Alprostadil Prostaglandin E1 Powder,
Erectile Dysfunction Alprostadil Powder,
CAS 745-65-3 Alprostadil Prostaglandin E1
Erectile Dysfunction PGE1 Alprostadil Prostaglandin E1
Whatsapp: +86 15202961574
The Introductction of PGE1 Prostaglandin E1
Alprostadil, also known as prostaglandin E1(PGE1), is extracted by an enzymatic process using sheep seminal vesicles and evening primrose oil as starting materials.
PGE1 is a bioactive substance widely present in the body and treats diabetic neuropathy by the following mechanisms.
1, Improve hemodynamics, by increasing the CAMP content in vascular smooth muscle cells, exerting its vasodilating effect and reducing peripheral resistance.
2, Improve blood rheology, PGE1 can inhibit platelet agglutination , reduce platelet hyperreactivity and thromboxane A 2 (TXA 2) levels, can inhibit platelet activation , promote the reversal of activated platelets around the thrombus , improve the deformability of red blood cells.
3, PGE1 can activate lipoproteinase and promote triglyceride hydrolysis to reduce blood lipids and blood viscosity;
4, PGE1 can stimulate vascular endothelial cells to produce tissue-type fibrinolytic substances (t-PA), which has a certain direct thrombolytic effect.
5, through the inhibition of free Caz in vascular smooth muscle cells, inhibit the release of norepinephrine from vascular sympathetic nerve endings, so that vascular smooth muscle diastole and improve microcirculation.
1. PGE1 Prostaglandin E1 used for the treatment of Erectile Dysfunction
2. PGE1 Prostaglandin E1 used in maintaining a patent ductus arteriosus in newborns.
3. PGE1 Prostaglandin E1 used as urethral suppositories and in injectable form.
4. PGE1 Prostaglandin E1 used for critical limb ischemia.
5. PGE1 Prostaglandin E1 used for diabetic neuropathy, myocardial infarction, thromboangitis, arteriosclerosis obliterans, central retinal vein thrombosis.