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API Pharmaceutical 98% Tacrolimus powder Immunosuppressive CAS 104987-11-3

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Tacrolimus
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram
Supply Ability: 5000kg/Month
Detail Information
MF: C44H71NO13 MW: 822.033
Appearance: White To Light Yellow Crystalline Powder CAS: 104987-11-3
Assay: 99% Melting Point: 127-129°

Product Description

 API Pharmaceutical 98% Tacrolimus powder Immunosuppressive CAS 104987-11-3

 

Production name  Tacrolimus
MOQ 1KG
CAS No. 109581-93-3
Appearance White crystalline powder
Molecular Formula C44H71NO13
Molecular Weight 822.033
Assay 99%

 

 

The Introduction of Tacrolimus:

 

Tacrolimus, isolated from the microorganism Streptomyces tsukubaensis, is a macrolide immunosuppressant developed by Fujisawa for organ transplantation. It displays similar but more potent immunosuppressive activity than cyclosporin. It inhibits both cell mediated and humoral immune responses.

In animal models of organ transplantation, tacrolimus has been shown to prolong survival of hepatic, renal, cardiac, small intestine, pancreatic and skin allografts and to reverse cardiac and renal allograft rejection. It has been used effectively in humans as rescue or primary immunosuppressant therapy in liver or kidney transplantation.

 

 

The Application & Function of Tacrolimus :

 

FK-506 (Tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system

 

API Pharmaceutical 98% Tacrolimus powder Immunosuppressive CAS 104987-11-3 0

 

The COA of Tacrolimus :

 

Items Specifications Result
Appearance White or almost white crystalline powder Conform
Identification IR
HPLC
Conform
Conform
Water 1.6% to 3.0% Max 2.2%
Residue on Ignition 0.2% Max 0.02%
Heavy Metals 20 PPM Max Conform
Ascomucin 0.8% Max 0.68%
Related Substances Dihydrotacrolimus 0.6% Max
Total Impurities 1.5% Max
0.46%
0.17%
Residual Solvents Aceton 2000PPM Max
Ethanol 2000PPM Max
Not Detected
Not Detected
Assay (dried basis) 98% to 102% 99.1%
Conclusion Conform with the Standards

 

 

API Pharmaceutical 98% Tacrolimus powder Immunosuppressive CAS 104987-11-3 1API Pharmaceutical 98% Tacrolimus powder Immunosuppressive CAS 104987-11-3 2API Pharmaceutical 98% Tacrolimus powder Immunosuppressive CAS 104987-11-3 3

Contact Details
Eric Tong

Phone Number : +8618220855851

WhatsApp : +8618629242069