|Place of Origin:||China|
|Minimum Order Quantity:||1KG|
|Packaging Details:||1.1kg/bag;25kg/drum 2. Inside: steril plastic bag+aluminum foil bag Outside: carton/drum|
|Payment Terms:||T/T, Western Union,, L/C, D/A, D/P|
|Supply Ability:||1 Metric tons per month|
|Product Name:||Lovastatin||Appearance:||White Powder|
|CAS No.:||75330-75-5||Molecular Formula:||C24H36O5|
|Shelf Life:||24months When Properly Stored||Purity:||99%min|
|HS Code:||2932999099||Function:||Regulating Blood Lipids|
|Storage Condition:||Store In Cool&dry Place, In Well-closed Containers.|
API Active Pharmaceutical Ingredient,
Human API Pharma Ingredients
Human Medcine Regulating Blood Lipids Drugs Lovastatin Powder CAS 75330-75-5
Lovastatin is a drug used in the cardiovascular system, which can prevent the development of arteriosclerosis and reduce the risk of myocardial infarction.
Lovastatin blocks endogenous cholesterol synthesis by inhibiting the rate-limiting enzyme HMG-CoA reductase of cholesterol synthesis, reduces intracellular cholesterol content, and feedingly increases the number of LDL receptors on the cell surface. The absorption and degradation of LDL particles in the blood circulation are accelerated, and the total cholesterol and very low density lipoprotein (VLDL), LDL and triglycerides in the plasma are reduced. As the conversion of HMG-CoA to mevalonate is an early step in the cholesterol biosynthesis pathway, the use of lovastatin does not cause the accumulation of potentially toxic cholesterol substances, and HMG-CoA can also be quickly reverse-metabolized into acetyl-coA and participate in other biosynthesis pathways in vivo. This inhibition effect is incomplete and reversible, and there is A dose-effect relationship. At therapeutic doses, the amount of cholesterol required for normal cell membrane function is not affected. Therefore, lovastatin has a significant lipid-lowering effect with few side effects.
Product analysis report
Batch No.: HNB20230205
Product Name: Lovastatin
Manufacture Date: 05th,Feb.,2023 Analysis Date: 05th,Feb.,2023 Expiry Date: 04th,Feb.,2025
Storage: Store in cool&dry place, in well-closed containers.
Shelf life: 24 Months when properly stored.
|Inspection Standard||Enterprise Standard Nutraceuticals Grade|
|Description||white powder||White powder|
|Identification IR||Similar with the Reference Spectrum||Complies|
|Optical Rotation||- 15.5° ~ - 17.5°||- 16.3°|
|Clearity and color of solution||Clear and colourless||Clear and colourless|
|Heavy Metals||Not more than 10ppm||Complies|
|Arsenic||Not more than 1ppm||Complies|
|Sulphates||Not more than 300ppm||Complies|
|Ammonium||Not more than 200ppm||Complies|
|Iron||Not more than 10ppm||Complies|
|Cadmium||Not more than 1ppm||Complies|
|Lead||Not more than 3ppm||Complies|
|Mercury||Not more than 0. 1ppm||Complies|
|Related Substances||Total||Not more than 2.0%||0.9%|
|GSSG||Not more than 1.5%||0.3%|
|Loss on Drying||Not more than 0.5%||0.2%|
|Residue on Ignition||Not more than 0. 1%||0.04%|
|Assay||98.0% to 101.0%||99.0%|
|Total plate count||≤1000cfu/g||Complies|
|Yeast and mold count||≤100cfu/g||Complies|
|Total coli forms||≤100cfu/g||Complies|
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