| Place of Origin: | China |
|---|---|
| Brand Name: | BCB |
| Certification: | ISO |
| Model Number: | Artesunate |
| Minimum Order Quantity: | 1 |
| Price: | 100 |
| Packaging Details: | 1kg/bag, 25kg/drum |
| Delivery Time: | 7 working days |
| Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram |
| Supply Ability: | 10000kg/month |
| Appearance: | White Powder | CAS No.: | 88495-63-0 |
|---|---|---|---|
| Purity: | 98% | MF: | C19H28O8 |
| MW: | 384.421 | Melting Point: | 132-135ºC |
| Shelf Life: | 24 Months | Storage: | Cool Dry Place |
| High Light: | API Active Pharmaceutical Ingredient,Human API Pharma Ingredients |
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98% Antimalarial Powder CAS 88495-63-0 Artesunate
| Product name | Artesunate |
| Appearance | White crystal Powder |
| CAS No. | 88495-63-0 |
| MF | C19H28O8 |
| Purity | 99% |
| Storage | Keep in cool dry place. |
The Introductction of Artesunate :
Artesunate is used primarily as treatment for malaria; it has also been shown to be >90% efficacious at reducing egg production in Schistosoma haematobium infection. According to WHO intravenous AS is the drug of choice for severe malaria both in children and adults where there is low transmission.In regions where transmission is high, randomized trials among Asian adults and African children strongly advocates the use of artesunate over quinine as the treatment of choice for falciparum malaria. Artesunate is prepared from dihydroartemisinin (DHA) by reacting it with succinic acid anhydride in basic medium. As base/solvent, sodium bicarbonate and catalyst DMAP have been used, with yields of up to 100%. A large scale process involves treatment of DHA with a mixture, a catalytic amount of DMAP and succinic anhydride. The mixture is stirred for 6-9 h to get artesunate in quantitative yield. The product is further re-crystallized. alpha-Artesunate is exclusively formed (m.p 135-137C)..
The Application & Function of Artesunate:
1. With function of controlling of vivax malaria and falciparum malaria symptom, as well as treatment of chloroquine-resistant strain of insect.
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