| Place of Origin: | China |
|---|---|
| Brand Name: | BCB |
| Certification: | ISO |
| Model Number: | Sitagliptin |
| Minimum Order Quantity: | 1 |
| Price: | 500 |
| Packaging Details: | 1kg/bag, 25kg/drum |
| Delivery Time: | 7 working days |
| Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram |
| Supply Ability: | 10000kg/month |
| Purity: | 99% | Mf: | C16h15f6n5o |
|---|---|---|---|
| Cas No.: | 486460-32-6 | Einecs No.: | 690-730-1 |
| Appearance: | White Powder | Usage: | Pharmaceutical Intermediates |
| Shelf Life: | 24 Month | Test Method: | HPLC |
| Melting Point: | 114.1-115.7 °c | ||
| High Light: | API Active Pharmaceutical Ingredient,Human API Pharma Ingredients |
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Diabetes Treatment API Raw Material Sitagliptin CAS 486460-32-6
| Production name | Sitagliptin |
| MOQ | 1KG |
| CAS No. | 486460-32-6 |
| Appearance | White to off white powder |
| Molecular Formula | C16H15F6N5O |
| Molecular Weight | 407.31 |
| Assay | 99% |
| Application | Pharma grade |
The Introductction of Sitagliptin :
Sitagliptin is the first novel dipeptidyl peptidase IV inhibitor from Merck for the treatment of type 2 diabetes without weight gain and the incidence of hypoglycemia was similar to placebo. Sitagliptin acts by enhancing the body's incretin system, which helps to regulate glucose by affecting β and α cells in the pancreas.
The Application & Function of Sitagliptin :
Sitagliptin is a useful pharmaceutical drug. Could be useful for treating intestinal inflammation, diabetes, pre-?diabetes, impaired glucose tolerance, hepatitis, and inflammatory liver disease.
The COA of Sitagliptin :
| Items | Specifications | Test results |
| Appearance | White crystalline powder | Conform |
| Solubility | Soluble in water | Conform |
| Identification |
IR HPLC RT |
Conform Conform |
| Melting point | 202.0~204.0°C | 202.0~203.0°C |
| Water (by KF) | ≤1.0% | 0.9% |
| Specific rotation | -18 ~ -23.0°(C=1.0 water) | -21.3° |
| Residue on ignition | ≤0.1% | 0.01% |
| Heavy metals | ≤20ppm | Conform |
| Chiral impurity | ≤1.0% | 0.02% |
| Related substances | Any single impurity≤0.5% | 0.01% |
| Total impurity≤1.0% | 0.05% | |
| Assay (by HPLC) | 98.0~102.0% | 99.4% |