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Diabetes Treatment API Raw Material Sitagliptin CAS 486460-32-6

Basic Information
Place of Origin: China
Brand Name: BCB
Certification: ISO
Model Number: Sitagliptin
Minimum Order Quantity: 1
Price: 500
Packaging Details: 1kg/bag, 25kg/drum
Delivery Time: 7 working days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram
Supply Ability: 10000kg/month
Detail Information
Purity: 99% Mf: C16h15f6n5o
Cas No.: 486460-32-6 Einecs No.: 690-730-1
Appearance: White Powder Usage: Pharmaceutical Intermediates
Shelf Life: 24 Month Test Method: HPLC
Melting Point: 114.1-115.7 °c
High Light:

API Active Pharmaceutical Ingredient

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Product Description

Diabetes Treatment API Raw Material Sitagliptin CAS 486460-32-6

 

Production name Sitagliptin
MOQ 1KG
CAS No. 486460-32-6
Appearance White to off white powder
Molecular Formula C16H15F6N5O
Molecular Weight 407.31
Assay 99%
Application Pharma grade

 

Diabetes Treatment API Raw Material Sitagliptin CAS 486460-32-6 0

 

The Introductction of Sitagliptin :

 

Sitagliptin is the first novel dipeptidyl peptidase IV inhibitor from Merck for the treatment of type 2 diabetes without weight gain and the incidence of hypoglycemia was similar to placebo. Sitagliptin acts by enhancing the body's incretin system, which helps to regulate glucose by affecting β and α cells in the pancreas.

 

The Application & Function of Sitagliptin :

Sitagliptin is a useful pharmaceutical drug. Could be useful for treating intestinal inflammation, diabetes, pre-?diabetes, impaired glucose tolerance, hepatitis, and inflammatory liver disease.

 

 

The COA of Sitagliptin  :

 

Items Specifications Test results
Appearance White crystalline powder Conform
Solubility Soluble in water Conform
Identification

IR

HPLC RT

Conform

Conform

Melting point 202.0~204.0°C 202.0~203.0°C
Water (by KF) 1.0% 0.9%
Specific rotation -18 ~ -23.0°(C=1.0 water) -21.3°
Residue on ignition ≤0.1% 0.01%
Heavy metals ≤20ppm Conform
Chiral impurity 1.0% 0.02%
Related substances Any single impurity0.5% 0.01%
Total impurity1.0% 0.05%
Assay (by HPLC) 98.0~102.0% 99.4%

 

 

Diabetes Treatment API Raw Material Sitagliptin CAS 486460-32-6 1Diabetes Treatment API Raw Material Sitagliptin CAS 486460-32-6 2Diabetes Treatment API Raw Material Sitagliptin CAS 486460-32-6 3

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