|Place of Origin:||China|
|Minimum Order Quantity:||1KG|
|Packaging Details:||Aluminum foil bag|
|Payment Terms:||L/C, D/A, D/P, T/T, Western Union, MoneyGram，Alibaba Assurance Order|
|Einecs No.:||259-559-6||Appearance:||White Crysalline Powder|
Antiparasitics Veterinary API 99% Praziquantel Powder for fish
The Introductction of Praziquantel
Praziquantel is a synthetic broad-spectrum anthelmintic that was discovered abroad in the 1970s.
Praziquantel is a colorless crystalline powder, odorless and slightly bitter, stable under normal conditions. It is soluble in chloroform, dimethyl sulfoxide and other organic solvents, slightly soluble in ethanol and insoluble in water.
Praziquantel has a significant effect on killing adult schistosomes. The mechanism of killing, from the molecular level, is that praziquantel rapidly disrupts the Ca2+ balance in the body of the worm, which leads to excitement and muscle contracture on the one hand, so that the parasitic schistosomes in the portal system can not be adsorbed in the blood vessel wall and carried into the liver by the blood flow (liver shift), and then damaged; secondly, the conductive Chemicalbook causes damage to the syncytial cortex of schistosomes, in addition to the absorption, excretion and secretion of the worm In addition to affecting the absorption, excretion and secretion functions of schistosomes, leading to disorders of glucose metabolism and enzyme systems, the antigenic determinants on the surface of the worm are exposed and recognized by the host's immune system, attracting a large number of inflammatory cells such as neutrophils, eosinophils and macrophages to gather around the worm and attack it.
Praziquantel is a broad-spectrum antiparasitic drug, an anthelmintic effective against Schistosoma japonicum, Schistosoma mansoni and Schistosoma egypti, Schistosoma mansoni, Schistosoma haematobium, Schistosoma capsulatum, Cestodes and Cysticerci. In particular, it has a powerful killing effect on cestodes and is one of the best schistosomiasis drugs available.
Praziquantel is active against both larvae and adults of many trematodes, and is the first choice for the treatment of schistosomes. It can also be used for the treatment of infections caused by Schistosoma haematobium, Schistosoma lungeri, Schistosoma hepatica, Schistosoma gingerbread, and Schistosoma posterior, as well as for the treatment of tapeworm and cysticercosis infections, and in combination with albendazole for the treatment of encysticercosis.
|Product Name||Praziquantel||Batch No.||HNB-220901|
|Standards||Comply with the requirement of USP32 standard|
|Issuing Date||2022.09.01||Expiry Date||2024.09.01|
|Test parameter||Test Limit||Results|
|Appearance||White crystalline powder||Conforms|
|Melting Point||136 ~ 142℃||141℃|
|Loss on Drying||≤0.5%||0.2%|
|Residue on Ignition||≤0.1%||0.01%|
|Related Substances||A ≤0.2%||0.01%|
|Conclusion||The above material complies with USP32|