| Place of Origin: | China |
|---|---|
| Brand Name: | BCB |
| Certification: | ISO |
| Model Number: | Omeprazole |
| Minimum Order Quantity: | 1 |
| Price: | 500 |
| Packaging Details: | 1kg/bag, 25kg/drum |
| Delivery Time: | 7 working days |
| Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram |
| Supply Ability: | 10000kg/month |
| Purity: | 99% | Mf: | C17h19n3o3s |
|---|---|---|---|
| Cas No.: | 73590-58-6 | Einecs No.: | 615-996-8 |
| Appearance: | White Powder | Usage: | Pharmaceutical Intermediates |
| Shelf Life: | 24 Month | Test Method: | HPLC |
| Melting Point: | 188-190°C | ||
| High Light: | API Active Pharmaceutical Ingredient,Human API Pharma Ingredients |
||
Pharamceutical Raw Material CAS 73590-58-6 Omeprazole
| Production name | Omeprazole |
| MOQ | 1KG |
| CAS No. | 73590-58-6 |
| Appearance | White to off white crystalline powder |
| Molecular Formula | C17H19N3O3S |
| Molecular Weight | 345.416 |
| Assay | 99% |
| Application | Pharma grade |
The Introductction of Omeprazole :
Omeprazole (omeprazole) is a kind of proton pump inhibitor used for the treatment of peptic ulcer and gastroesophageal reflux disease (GERD) and other diseases. The active form of sulfonamide is then irreversibly combined with the sulfhydryl group of the proton pump through a disulfide bond to generate a complex of sulfenamide and proton pump (H+-K+-ATPase), thereby inhibiting the enzyme activity and making the intracellular H+ cannot be transported into the gastric cavity, blocking the final step of gastric acid secretion, which can greatly reduce the amount of gastric acid in the gastric juice. Therefore, this product has a strong and long-lasting inhibitory effect on gastric acid secretion caused by various reasons (such as basal gastric acid secretion and gastric acid secretion caused by histamine, pentagastrin and stimulation of the vagus nerve, including the inability of H2 receptor blockers. Inhibited gastric acid secretion by dibutyl cyclic adenylate). This has a certain relationship with the irreversibility of the inhibitory effect of this product on the proton pump, and the acid secretion can be restored only after the formation of a new proton pump.
The Application & Function of Omeprazole :
The COA of Omeprazole :
| items | standards | results |
| appearance | white or almost white powder | complies |
| solubility | very slightly soluble in water,soluble in methylene chlori,sparingly soluble in ethanol(96 per cent)and in methano it dissolves in dilute solutions of alkali hydroxides | complies |
| identification | IR | complies |
| appearance of solution | solution S is clear | complies |
| impurities F and G | absorbance of solution S:0.10max | 0.0085 |
| related substances | impurity D:0.10%max | 0.030% |
| impurity E:0.10%max | 0.012% | |
| any individual unspecified impurity:0.10%max | not detected | |
| total:0.5% max | 0.04% | |
| loss on drying | 0.2% max | 0.09% |
| residual solvents | methylene chlori:600ppm max | not detected |
| methan:3000ppm max | 98ppm | |
| sulfated ash | 0.1%max | 0.04% |
| particle size | D50:2μm~3μm | 2μm |
| D90:5μm~7μm | 6μm | |
| assay | 99.0%~101.0% | 99.8% |