Place of Origin: | China |
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Brand Name: | HNB |
Certification: | ISO |
Model Number: | Sulfamethoxazole |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually3-5days |
Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order |
Supply Ability: | 5000kg/Month |
CAS: | 723-46-6 | Mf: | C10H11N3O3S |
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MW: | 253.28 | Specification: | 99% |
EINECS No.: | 211-963-3 | Appearance: | White Crystalline Powder |
Sample: | Available | ||
High Light: | Antibacterial Agent Sulfamethoxazole Powder,Veterinary API 723-46-6,Veterinary API Sulfamethoxazole Powder |
99% Sulfamethoxazole Powder Veterinary API Antibacterial agent CAS 723-46-6
Product name |
|
Appearance |
White Crystalline Powder |
CAS |
723-46-6 |
MF |
C10H11N3O3S |
Purity |
99% |
Storage |
Keep in cool dry place. |
The Introductction of Sulfamethoxazole
Sulfamethoxazole, also known as Synthroid, is a broad-spectrum antimicrobial agent with particularly strong effects on Staphylococcus and Escherichia coli, and is used to treat urinary tract infections as well as avian cholera. Sulfamethoxazole is a medium-acting sulfa drug for systemic application, which can act competitively with PABA on dihydrofolate synthase in bacteria to prevent the synthesis of dihydrofolate in bacteria, thus inhibiting the growth and reproduction of bacteria. With sulfadiazine, sulfisoxazole, trisulfadiazine three sulfonamides are currently better drugs for the treatment of nocardia. Half-life of 10-12 hours, can be partially acetylated.
Sulfamethoxazole is a white crystalline powder, odorless and slightly bitter in taste. Melting point 168℃. Very slightly soluble in water, easily soluble in dilute acid, dilute alkali solution or ammonia.
Sulfamethoxazole has wide antibacterial spectrum and fast absorption. Strong antibacterial effect, antibacterial effect on most gram-positive and negative bacteria, the bacteria produce resistance to this product slowly. It is suitable for respiratory system infection, urinary system infection, intestinal tract infection, local soft tissue or skin purulent infection, etc. Because of the slow excretion, the effective concentration in blood lasts longer.
The Application & Sulfamethoxazole
Sulfamethoxazole is particularly effective against Staphylococcus and Escherichia coli as an antibacterial agent. It is mainly used for the treatment of avian cholera, etc.
Sulfamethoxazole, as an anti-infective agent, is used for the prevention of urinary tract infections, respiratory tract infections, intestinal infections, Salmonella spp. infections, pediatric acute otitis media, and rheumatoid encephalitis.
Sulfonamides, mainly used for the treatment of acute and chronic urinary tract infections, also used for the prevention of meningitis and acute otitis media caused by H. influenzae, etc.
Other Name of Sulfamethoxazole:
sulfomethoxazole
sulfamethoxazole
Sulphamethoxazole
Sulfamethoxazole solution
5-Methyl-3-sulfanilamidoisoxazole
3-Sulfanilamido-5-methylisoxazole
5-Methyl-3-sulfonylamidoisoxazole
5-methyl-3-sulfanylamidoisoxazole
3-Sulphanilamido-5-methylisoxazole
N1-(5-methylisoxazol-3-yl)sulphanilamide
3-(p-aminophenylsulfonamido)-5-methylisoxazole
3-(para-Aminophenylsulphonamido)-5-methylisoxazole
4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide
4-amino-n-(5-methyl-3-isoxazolyl)-benzenesulfonamid
The COA of Sulfamethoxazole
Product Name: Sulfamethoxazole |
Pharmacopoeia: USP-NF |
Batch No.: A-3021205017 |
Batch Quantity: 2017.665kg |
CAS No.: 723-46-6 |
Manufacture Date: 8th, May., 2022 Analysis Date: 10th, May., 2022 Expiry Date: Apr., 2027 |
Storage: Store in cool&dry place, in well-closed containers. |
Shelf life: 5 Years when properly stored. |
ITEMS OF ANALYSIS | SPECIFICATIONS | RESULT |
Characters | White or almost white crystalline powder | Complies |
Identification |
IR: Complies with reference spectroscopy (USP<197K>)
|
Complies |
HPLC: RT of major peak of sample solution corresponds to that of standard solution | Complies | |
Loss on drying | ≤ 0.5% (USP<731>) | 0.09% |
Residue on ignition | ≤ 0.1% (USP<281>) | 0.02% |
Related substances | Impurity A ≤ 0.10% | Not Detected |
Impurity B ≤ 0.10% | 0.03% | |
Impurity C ≤ 0.10% | Not Detected | |
Sulfanilic acid ≤ 0.10% | Not Detected | |
Sulfanilamide ≤ 0.10% | Not Detected | |
Impurity F ≤ 0.10% | 0.02% | |
Any other impurity ≤ 0.10% | 0.01% | |
Total impurities ≤ 0.30% | 0.07% | |
Assay (on dry basis) | 98.0%~102.0% (USP<621>) | 99.2% |
Conclusion | Complies with the USP-NF standard |