| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Piroxicam |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually3-5days |
| Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram，Alibaba Assurance Order |
| Supply Ability: | 5000kg/Month |
| CAS: | 36322-90-4 | Mf: | C15H13N3O4S |
|---|---|---|---|
| MW: | 331.35 | Specification: | 99% |
| Melting Point: | 198-200°C | Appearance: | Off-white To Light Yellow Crystalline Powder |
| Sample: | Available | ||
| High Light: | 36322-90-4 Antipyretic Analgesic,Analgesic Piroxicam Powder,API Pharmaceutical Piroxicam Powder |
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Pharmaceutical Antipyretic Analgesic API 99% Piroxicam Powder CAS 36322-90-4
|
Product name |
Piroxicam |
|
Appearance |
Off-white to light yellow crystalline powder |
|
CAS |
36322-90-4 |
|
MF |
C15H13N3O4S |
|
Purity |
99% |
|
Storage |
Keep in cool dry place. |
The Introductction of Piroxicam
Piroxicam is off-white or slightly yellow-green crystalline powder, odorless and tasteless. Almost insoluble in water, slightly soluble in ethanol or ether, easily soluble in chloroform, slightly soluble in acetone, soluble in acid.
Piroxicam is a long-acting non-steroidal anti-inflammatory analgesic and antipyretic drug with analgesic, anti-inflammatory and antipyretic effects. Piroxicam exerts its pharmacological effects by inhibiting cyclooxygenase, reducing the synthesis of local prostaglandins in tissues and inhibiting the chemotaxis of leukocytes and the release of lysosomal enzymes. Tmax3~5h. T1/2 is 30~86h, PPB is more than 90%, T1/2 is prolonged in patients with renal insufficiency, mainly metabolized by the liver. Due to the long T1/2, a single dose can maintain a relatively stable blood concentration for 24h, and multiple doses can easily lead to accumulation. The effective blood concentration is 1.5~2μg/ml. stable blood concentration can be reached only 7~12d after starting treatment. 66% is excreted from kidney, 33% is excreted from feces, and <5% is in its original form.
The Application & Function of Piroxicam
Piroxicam is a non-steroidal anti-inflammatory drug with antipyretic, analgesic and anti-inflammatory effects.
Piroxicam is indicated for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute muscular human bone injury and acute gout.
Piroxicam in the treatment of rheumatic and rheumatoid arthritis, has a more obvious analgesic, anti-inflammatory and certain anti-clock effect, its effect is slightly stronger than indomethacin.
Other Name of Piroxicam:
Feldene;Pipoxicam;Prioxicam;4-HYDROXY-2-METHYL-3-(PYRID-2-YL-CARBAMOYL)-2H-1,2-BENZOTHIAZINE 1,1-DIOXIDE;Baxo;Erazon;Pirkam;Riacen;Zunden;chf1251
The COA of Piroxicam
| Product Name | Piroxicam | Batch No. | HNB-190302 |
| Quantity | 100kg | Test Sample | 10g |
| Manuf.Date | 2022.12.02 | Test Date | 2022.12.02 |
| Issuing Date | 2022.12.02 | Expiry Date | 2024.12.01 |
| Test parameter | Test Iimit | Results | |
| Appearanco | Off-white to light yellow crystalline powder | Light yellow crystalline Powder | |
| Identification | A: IR | Conforms | |
| B: HPLC | Conforms | ||
| Solubility | Easily soluble in trichloromethane, slightly soluble in acetone, slightly soluble in ethanol or ether, almost insoluble in water; soluble in acid, slightly soluble in alkali. | Conforms | |
| Assay | ≥98.5% | 99.6% | |
| Choride | ≤ 0.1% | 0.03% | |
| Melting point |
198~202℃
|
200℃ | |
| Related Substances | Individual impurity: ≤0.5% | Conforms | |
| Total impurties: ≤1.0% | Conforms | ||
| Residue on Ignition | ≤0.1% | 0.03% | |
| Heavy metals | ≤10ppm | Conforms | |
| As | ≤ 2ppm | Conforms | |
| Loss on drying | ≤05% | 0.3% | |
| Conclusion | The above material complies with USP 43 standard | ||
