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Pharmaceutical API Raw Material 99% Phenylephrine Hydrochloride Powder CAS 61-76-7

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Phenylephrine Hydrochloride
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 61-76-7 Mf: C9H14ClNO2
MW: 203.67 Specification: 99%
EINECS No.: 200-517-3 Appearance: White Crystalline Powder
Sample: Available
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Pharmaceutical Phenylephrine Hydrochloride Powder

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CAS 61-76-7 API Pharmaceutical

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Phenylephrine Hydrochloride API Raw Material


Product Description

Pharmaceutical API Raw Material 99% Phenylephrine Hydrochloride Powder CAS 61-76-7

Pharmaceutical API Raw Material 99% Phenylephrine Hydrochloride Powder CAS 61-76-7 0

Product name

Phenylephrine Hydrochlorid

Appearance

White crystalline powder

CAS

61-76-7

MF

C9H14ClNO2

Purity

99%

Storage

Keep in cool dry place.

Pharmaceutical API Raw Material 99% Phenylephrine Hydrochloride Powder CAS 61-76-7 1

 

The Introductction of Phenylephrine Hydrochloride

 

Phenylephrine hydrochloride is a white or off-white crystalline powder. Melting point 140-145℃. Soluble in water and ethanol, insoluble in chloroform and ether. The melting point of levorotatory free base is 169-172℃.


Dosage of Phenylephrine Hydrochloride.
1. Common dosage for adults.
(1) vasoconstriction, local anesthetic solution can add 1mg of this product in every 20ml to reach 1:20000 concentration; subarachnoid block, every 2-3ml to reach 1:1000 concentration.
(2) Elevated blood pressure, mild or moderate hypotension, intramuscular injection of 2-5mg, re-administration interval not shorter than 10-15 minutes, intravenous injection of 0.2mg once, as needed every 10-15 minutes.
(3) Paroxysmal supraventricular tachycardia, the initial amount of intravenous injection of 0.5mg, injected within 20-30 seconds, later the dosage increases, each time the amount of additional drug does not exceed 0.1-0.2mg, once the amount of 1mg is limited.
(4) Severe hypotension and shock (including drug-related hypotension) can be administered intravenously, 5% glucose injection or 0.9% sodium chloride injection with 10mg of this product per 500ml (1:50000 concentration), the initial drip rate is 100-180 drops per minute, after the blood pressure stabilization decreases to 40-60 drops per minute, if necessary, the concentration can be doubled, the drip rate is adjusted according to the blood pressure. If necessary, the concentration can be doubled, and the rate of drip is adjusted according to the blood pressure.
(5) To prevent hypotension during subarachnoid block, 2-3 mg of this product can be injected intramuscularly 3-4 minutes before the block.

 

The Application & Function of Phenylephrine Hydrochloride

 

Phenylephrine hydrochloride is an epinephrine-like drug. Has a constricting effect on local body blood vessels.


Phenylephrine hydrochloride is used for prolonging local anesthesia for surgical procedures and for decongesting and decongesting nasal mucous membrane congestion.


Phenylephrine hydrochloride is used for prolonging local time in surgery, decongesting nasal mucous membrane congestion, pupil dilation in ophthalmology, and boosting acute hypotension, and cold medicine.

 

Other Name of Phenylephrine Hydrochloride

 

Phenylephrine HCL
L(-)-PHENYLEPHRINE HCL
PHENYLEPHRINE HYDROCHLORIDE
Phenylephrine Hydrochloride
L-Phenylephrine hydrochloride
L(-)-Phenylephrine hydrochloride
d-(-)-phenylephrinehydrochloride
Phenylephrine Hydrochloride (200 mg)
L-(3-HYDROXYPHENYL)-N-METHYLETHANOLAMINEHYDROCHLORIDE
L-1-(M-HYDROXYPHENYL)-2-METHYLAMINOETHANOL HYDROCHLORIDE
(-)-3-[1(R)-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride
(R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
L-A-HYDROXY-B-METHYLAMINO-3-HYDROXY-1-ETHYLBENZENE HYDROCHLORIDE
(R)-3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
(-)-3-HYDROXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL HYDROCHLORIDE
PHENYLEPHRINE HCL BP ((R)-3-HYDROXY-ALPHA-(METHYLAMINO) METHYL] BENZENEMETHANOLHYDROCHL ORIDE)

 

The COA of Phenylephrine Hydrochloride

 

Batch No.: HNB221224
Product Name: Phenylephrine Hydrochloride
CAS No.: 61-76-7
Manufacture Date: Dec.24th,2022                    Expiry Date: Dec.23th,2024
Sample Date: Dec.25th,2022                            Alalysis Date: Dec.25th,2022
Storage: Store in cool&dry place, in well-closed containers.
Shelf life: 24 Months when properly stored.
Reference standard: USP38
 
ITEMS OF ANALYSIS SPECIFICATIONS RESULT
Appearance White or off-white crystalline powder Complies
Identification Complies Complies
Solubility Soluble in water or ethanol, insoluble in trichloromethane or ether. Complies
Melting Point
140~145℃
143℃
pH 4.5~5.5 4.9
Adrenalone ≤0.2(A310nm) 0.037
Loss on drying ≤ 1.0% 0.3%
Residue on ignition ≤ 0.2% <0.05%
Assay 98%~102% 99.4%
Conclusion Complies with the USP38 standard

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