Place of Origin: | China |
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Brand Name: | HNB |
Certification: | ISO |
Model Number: | Rifampicin |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually 3-5 days |
Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order |
Supply Ability: | 5000kg/Month |
CAS: | 13292-46-1 | Mf: | C43H58N4O12 |
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MW: | 822.94 | Specification: | 99% |
Flash Point: | 183 ℃ | Appearance: | White Powder |
EINECS: | 236-312-0 | Sample: | Available |
High Light: | Pharmaceutical Rifampicin Powder,API Pharmaceutical 13292-46-1,Rifampicin Powder 99% |
CAS 13292-46-1 API Pharmaceutical Rifampicin 99%
Product name |
Rifampicin |
Appearance |
Red Powder |
CAS |
13292-46-1 |
MF |
C43H58N4O12 |
Purity |
99% |
Storage |
Keep in cool dry place. |
The Introductction of Rifampicin
Rifampicin, chemical name of which is 3 - [[(4-methyl-1-piperazinyl) imino] methyl] rifamycin, is an organic compound, chemical formula of which is C43H58N4O12. It is a broad-spectrum antibiotic drug belonging to the rifamycin family. It has strong antibacterial effect on tuberculosis, and also has curative effect on gram-positive or negative bacteria, viruses, etc. It is mainly used to treat tuberculosis, meningitis, and staphylococcus aureus infections, External use can treat trachoma, etc.
The Application & Function of Rifampicin
Rifampicin is a semi synthetic broad-spectrum antibacterial agent of rifamycin class, which is applicable to a variety of pathogenic microorganisms
Antibacterial activity. The drug has obvious bactericidal effect on Mycobacterium tuberculosis and some non tuberculosis mycobacteria (including Mycobacterium leprae, etc.) both inside and outside the host cells. Rifampicin has a good antibacterial effect on aerobic gram-positive bacteria, including staphylococcal enzyme producing strains and methicillin resistant strains, Streptococcus pneumoniae, other streptococci, enterococcus, listeria, anthrax, pneumococcus, diphtheria, anaerobes, etc.
It also has high antibacterial activity against aerobic gram-negative bacteria such as Neisseria meningitidis, Haemophilus influenzae and Neisseria gonorrhoeae. Rifampicin also has a good effect on Legionella, and has an inhibitory effect on chlamydia trachomatis, lymphogranuloma of sexually transmitted diseases, psittacosis and other pathogens. The bacteria were cross resistant to rifamycin antibiotics. Rifampicin and DNA dependent RNA polymerase β The subunit is firmly bound to inhibit the synthesis of bacterial RNA, prevent the enzyme from connecting with DNA, thus blocking the RNA transcription process and stopping the synthesis of DNA and protein.
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The COA of Rifampicin
ITEMS OF ANALYSIS |
SPECIFICATION
|
RESULT |
Characteristics | Red crystalline powder, odorless or practically odorless and practically tasteless | Complies |
Identification | IR: The infrared absorption spectrum should be concordant with the reference spectrum | Complies |
Solubility | Soluble in ethanol, chloroform, almost insoluble in water. | Complies |
Water
|
≤0.5% | 0.1% |
ash content
|
≤0.5% | 0.2% |
Assay
|
99% | 99.80% |
Conclusion
|
Conform with the standard |
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