| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO coa |
| Model Number: | HNB-Phenothiazine |
| Minimum Order Quantity: | 1kg |
| Price: | 138 |
| Packaging Details: | 25kg |
| Delivery Time: | 5-10 |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram |
| Supply Ability: | 50000 |
| Name: | Phenothiazine | CAS: | Phenothiazine |
|---|---|---|---|
| MF: | C13H8N2S | MW: | 166.22 |
| Whatsapp: | +86152 029 61574 | ||
| High Light: | Thiodiphenylamine Pesticides Raw Materials,Phenothiazine Pesticides Raw Materials,2-Cyano-Phenothiazine Powder |
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Pesticides Raw Materials CAS 38642-74-9 2-Cyano-Phenothiazine Thiodiphenylamine
| Product name: | Phenothiazine | ||||||||||||||||
| Molecular formula : | C12H9NS | ||||||||||||||||
| Molecular weight: | 166.22 | ||||||||||||||||
| Quality Index : |
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| Shape and properties: | light yellow or light yellow crystalline powder | ||||||||||||||||
| Industrial standard: |
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Whatsapp:+86 15202961574
Phenothiazines are neuroleptic agents that affect a variety of receptors including dopaminergic receptor sites. Phenothiazines are used to treat psychosis including schizophrenia; violent, agitated, disturbed behavior; and mania secondary to bipolar disorder. Other uses include treatment of pain, headache, hiccups, acute severe anxiety, idiopathic dystonia, withdrawal, taste disorders, leishmaniasis, acute intermittent porphyria, and alleviation of nausea and vomiting. Phenothiazines allow smoother induction of anesthesia, potentiate anesthetic agents, and treat behavioral symptoms secondary to Alzheimer disease and senile dementia. Some phenothiazines exert an antipruritic effect and are useful for the treatment of neurodermatitis and pruriginous eczema, and relieve psychogenic itching.
Phenothiazine is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis. In addition, these agents have peripherally or centrally antagonistic activity against alpha adrenergic, serotonergic, histaminic, and muscarinic receptors.
Phenothiazines are used to treat serious mental and emotional disorders, including schizophrenia and other psychotic disorders. Some are used also to control agitation in certain patients, severe nausea and vomiting, severe hiccups, and moderate to severe pain in some hospitalized patients. Chlorpromazine is used also in the treatment of certain types of porphyria, and with other medicines in the treatment of tetanus. Phenothiazines may also be used for other conditions as determined by your doctor.
| Item | Standard | Results |
| Appearance | Yellow to yellow-green crystalline powder | Yellow crystalline powder |
| Identification-Melting pointHPLC | ≥202ºCThe same retain time with reference standard | 203.5ºCConform |
| Actonic solution appearance | ≤standard II | Conform |
| Assay(HPLC) | ≥98.5% | 99.7% |
| Loss of drying | ≤0.5% | 0.1% |
| Sulphated ash | ≤0.5% | 0.1% |
| Impurity | ||
| Sulfoxyde | ≤0.2% | <0.1 |
| Amide | ≤0.5% | <0.1 |
| Phenothiazine | ≤0.2% | No detected |
| 2-Chorophenothiazine | ≤0.5% | <0.1 |
| 2-Bromophenothiazine | ≤0.1% | No detected |
| Dimer | ≤0.3% | 0.15% |
| Unknow single impurity | ≤0.2% | <0.1 |
| Total impurity | ≤1.5% | 0.3% |
