Pharmaceutical API Raw Material 99% Gentamycin Sulfate Powder CAS 1405-41-0

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Gentamycin sulfate
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 1405-41-0 Mf: C(19-21)H(39-43)N5O7·H2SO4
MW: 533.36 Specification: 99%
EINECS No.: 215-778-9 Appearance: White Crystalline Powder
Sample: Available
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Gentamycin Sulfate Pharmaceutical API Raw Material


99% Gentamycin Sulfate Powder


CAS 1405-41-0 Gentamycin Sulfate Powder

Product Description

Pharmaceutical API raw material 99% Gentamycin sulfate Powder CAS 1405-41-0

Pharmaceutical API Raw Material 99% Gentamycin Sulfate Powder CAS 1405-41-0 0

Product name

Gentamycin sulfate


White Crystalline Powder








Keep in cool dry place.

Pharmaceutical API Raw Material 99% Gentamycin Sulfate Powder CAS 1405-41-0 1


The Introductction of Gentamycin sulfate


Gentamycin sulfate is an organic substance with the chemical formula C60H125O22N15-H2SO4, white or off-white crystalline powder, moisture-attracting, easily soluble in water, insoluble in lipids, insoluble in organic solvents, chemically stable, more stable to changes in temperature and acidity, pH 4.0-6.0 in 4% aqueous solution.


Gentamycin sulfate is an aminoglycoside antibiotic. It has good antibacterial effect on various Gram-negative bacteria and Gram-positive bacteria, and has good antibacterial effect on various Enterobacteriaceae such as Escherichia coli, Klebsiella, Aspergillus, Salmonella, Shigella, Enterobacter, Serratia and Pseudomonas aeruginosa.
Neisseria spp. and Haemophilus influenzae are moderately sensitive to gentamicin sulfate.

Gentamycin sulfate also has some effect on Brucella spp, Bacillus subtilis, Bacillus immobilis, and Campylobacter fetus.
Gentamycin sulfate has good antibacterial effect on about 80% of methicillin-sensitive strains of Staphylococcus spp. (including Staphylococcus aureus and coagulase-negative Staphylococcus), but methicillin-resistant strains are mostly resistant to gentamicin sulfate.
Gentamycin sulfate is less effective against Streptococcus spp. and Streptococcus pneumoniae, while Enterococcus spp. are mostly resistant to this product.
Gentamycin sulfate is combined with β-lactams, most of them can obtain synergistic antibacterial effect.


The mechanism of action of Gentamycin sulfate is to bind to the 30S subunit of bacterial ribosome and inhibit bacterial protein synthesis.


The Application & Function of Gentamycin sulfate


Gentamycin sulfate is clinically used for sepsis, respiratory tract infection, biliary tract infection, purulent peritonitis, intracranial infection, urinary tract infection and bacillary dysentery caused by Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Bacillus dysenteriae, Klebsiella, Bacillus deformans and other sensitive bacteria.


1. Gentamycin sulfate used for the treatment of serious infections caused by sensitive gram-negative bacilli, such as Escherichia coli, Klebsiella, Enterobacter, Aspergillus, Serratia, Pseudomonas aeruginosa and staphylococcal methicillin-sensitive strains, such as sepsis, lower respiratory tract infections, intestinal infections, pelvic infections, abdominal infections, skin soft tissue infections, complicated urinary tract infections, etc. The treatment of abdominal infection and pelvic infection should be combined with anti-anaerobic drugs, and gentamicin is mostly used clinically in combination with other antibacterial drugs. Combined with penicillin (or ampicillin) can be used to treat enterococcal infections.


2. Gentamycin sulfate used for central nervous system infection caused by sensitive bacteria, such as meningitis, ventriculitis, can be used at the same time with the product intrathecal injection as an adjuvant treatment.


Other Name of Gentamycin sulfate:


GENTAMICIN SULPHATE STERILE;Gentak;U-gencin;GENTAMICIN 2,5-SULFATE HYDRATE;100ppm;Pangram;sch9724;Gentalin;Genticyn;Septopal


The COA of Gentamycin sulfate


CAS number 1405-41-0 Product Name Gentamycin Sulfate
Manufacture Date: 20th Jan,2022 Analysis Date: 21th Jan, 2022
Batch NO.: HNB220120-1 Expiry Date: 19th Jan, 2024
Storage: Store in cool&dry place, in well-closed containers.
Shelf life: 24 Months when properly stored.


Appearance White or yellowish white powder,odorless or almost bygroscopic Complies
Assay(HPLC) ≥6801u/mg 6871u/mg
Solubility Very soluble in water,insoluble in acetone,chloroform,ether Complies
Identification A:B:C the positive reaction Complies
Specific rotation +53.5° ~ +59° +58.0°
PH 5.0 ~ 7.5 6.7
Impurity A ≤ 0.2% Complies
Impurity C 3%~15% Complies
Any other impurity Not more than area of the principal peak in the chromatogram obtained with RS(B)5% Complies
Total other impurity

Not more than 3times the area of the principal peak in the

Chromatogram obtained with RS(B)15%

Loss on drying ≤8.0% 5.0%
Sulphate 27.0 ~ 31.0% 28.4%
Sulphate ash ≤1.0% 0.2%
Microcount limit test ≤500col/g Complies
yeast and molds ≤10col/g Complies
Escherichia coil Absent Complies
Psuedo monas Absent Complies
Conclusion Meet with the USP standard

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