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CAS 2058-46-0 Veterinary API Raw Material Pure Oxytetracycline Hydrochloride Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Oxytetracycline hydrochloride
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 2058-46-0 Mf: C22H25ClN2O9
MW: 533.36 Specification: 99%
EINECS No.: 218-161-2 Appearance: Yellow Crystalline Powder
Sample: Available
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Pure Oxytetracycline Hydrochloride Powder

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CAS 2058-46-0 Veterinary API

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Veterinary Oxytetracycline Hydrochloride Powder


Product Description

Veternary API raw material pure Oxytetracycline hydrochloride Powder CAS 2058-46-0​

CAS 2058-46-0 Veterinary API Raw Material Pure Oxytetracycline Hydrochloride Powder 0

Product name

Oxytetracycline hydrochloride

Appearance

Yellow Crystalline Powder

CAS

2058-46-0

MF

C52H100N16O17S

Purity

99%

Storage

Keep in cool dry place.

CAS 2058-46-0 Veterinary API Raw Material Pure Oxytetracycline Hydrochloride Powder 1

 

The Introductction of Oxytetracycline hydrochloride

 

Doxycycline hydrochloride is a tetracycline antibiotic.


Doxycycline hydrochloride is a broad-spectrum antibacterial agent, many rickettsiae, mycoplasma, chlamydia, spirochetes, amoeba and some malaria parasites are also sensitive to this product. Alias: Dicyclomycin, oxytetracycline. It is a broad-spectrum antibacterial agent, many rickettsiae, mycoplasma, chlamydia, spirochetes, amoeba and some malaria parasites are also sensitive to this product. Enterococcus spp. are resistant to it. Other genera such as Actinomyces, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nucleus, Vibrio, Brucella, Campylobacter, Yersinia, etc. are sensitive to this product.

 

Oxytetracycline hydrochloride is yellow crystalline powder; odorless, moisture-attracting; darkens in daylight, easily destroyed in alkali solution. It is easily soluble in water, slightly soluble in methanol or ethanol, insoluble in ether.

 

The Application & Function of Oxytetracycline hydrochloride

 

Oxytetracycline hydrochloride is used as an elective agent for (1) rickettsial diseases, including epidemic typhus, endemic typhus, Rocky Mountain fever, scrub typhus and Q fever. (2) Mycoplasma spp. infections. (3) Chlamydia spp. infections, including parrot fever, venereal disease, lymphogranuloma, nonspecific urethritis, tuberculosis, cervicitis, and trachoma. (4) Regression fever. (5) Brucellosis. (6) Cholera. (7) Rabbit fever. (8) Plague. (9) Soft chancre.
The treatment of brucellosis and plague needs to be combined with aminoglycosides.

 

Due to the serious resistance of common pathogenic bacteria to hygromycin hydrochloride, it can be used as the drug of choice only when the pathogenic bacteria are sensitive to this product; Escherichia coli, Enterobacter aerogenes, Fusobacterium loxodes, Shigella spp., Haemophilus influenzae (limited to respiratory tract infections) and Klebsiella spp. (limited to respiratory and urinary tract infections) and other gram-negative bacillus infections that are sensitive to hygromycin hydrochloride.


Oxytetracycline hydrochloride should not be used for any type of staphylococcal or hemolytic streptococcal infections.

 

Oxytetracycline hydrochloride may be used in patients with tetanus, gas gangrene, yaws, syphilis, gonorrhea and leptospirosis, as well as Actinomyces spp. and Listeria monocytogenes infections who are allergic to penicillins.

 

Oxytetracycline hydrochloride may be used as an adjunctive therapy in patients with acute intestinal amebiasis and moderate to severe acne.

 

Other Name of Oxytetracycline hydrochloride:

 

Oxytetracycline hydrochloride
5-hydroxytetracycline hydrochloride
(4s-(4alpha,4aalpha,5alpha,5aalpha,6beta,12aalpha))-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride
Oxytetracycline HCL
OTC HCL
(2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
(3E,11S)-3-[amino(hydroxy)methylidene]-4a,6,7,11,12-pentahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride
(4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
Oxytertracycline HCL
10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-monohydrochloride

 

The COA of Oxytetracycline hydrochloride

 

Product Name: Oxytetracycline Hydrochloride

Batch Number: HNB220415

Batch Quantity: 800kg

Manufacture Date: 15th, Apr.,2022    Analysis Date: 16th, Apr.,2022    Expiry Date: 14th, Apr.,2024

Storage: Store in cool & dry place. Store in well-closed containers.

Shelf life: 24 Months when properly stored.

 

Items Specification Results
Characters Yellow crystalline powder Conforms
Identification A. Thin-layer chromatography results Conforms
B. Colour reaction with sulfuric acid Conforms
C. Give reaction of chlorides Conforms
pH 2.0 ~ 3.0 2.4
Specific optical rotation -188°~ -200° -195°
Specific absorbance 270nm ~ 290nm 273nm
Light-absorbing impurities 430nm A≤0.50 0.15
490nm A≤0.20 0.02
Related substances Impurity A ≤0.5% 0.02%
Impurity B ≤2.0% 0.60%
Impurity C ≤2.0% 0.80%
Total impurity of D,E,F ≤2.0% 0.20%
4-Epianhydrotetracycline ≤0.5% 0.07%
Total impurities ≤3.0% 1.80%
Heavy metals ≤50ppm <50ppm
Loss on drying ≤2.0% 0.60%
Sulphated Ash ≤0.5% 0.04%
Assay 95.0% ~ 102.0% 98.5%
Conclusion: The above certificate of analysis complies with BP2020

 

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