|Place of Origin:||China|
|Model Number:||Colistin sulfate|
|Minimum Order Quantity:||1KG|
|Packaging Details:||Aluminum foil bag|
|Payment Terms:||L/C, D/A, D/P, T/T, Western Union, MoneyGram，Alibaba Assurance Order|
|EINECS No.:||215-034-3||Appearance:||White To Yellowish Powder|
Pure Colistin Sulfate Powder API,
Veterinary API Colistin Sulfate Powder
Veternary API raw material pure Colistin sulfate Powder CAS 1264-72-8
The Introductction of Colistin sulfate
Colistin Sulfate is white or almost white powder, odorless, bitter with moisture-attracting property, easily soluble in water, slightly soluble in methanol, ethanol, almost insoluble in acetone, ether, etc. The free base is slightly soluble in water. It is stable in the range of PH3-7.5.
Colistin Sulfate is produced by Bacillus polymyxa and has a strong antibacterial effect on Gram-negative bacteria and is used to treat intestinal diseases caused by Gram-negative bacteria. It is better in combination with sulfadiazine effect.
Colistin Sulfate is a narrow-spectrum antibiotic. It mainly has strong antibacterial effect on Gram-negative bacteria, and the sensitive bacteria are Pseudomonas aeruginosa, Escherichia coli, Enterobacter spp, Klebsiella spp, Salmonella spp, Shigella spp, Pasteurella spp and Vibrio spp. And Aspergillus spp., Brucella spp., Serratia spp. and all Gram-positive bacteria are resistant to this product. Polymyxins are slow-acting bactericides, mainly acting on bacterial cell membranes. When in contact with sensitive bacteria, the free amino group (positively charged) in their chemical structure binds with the phosphate of phosphate (negatively charged) on bacterial cell membranes, increasing membrane permeability and causing leakage of important intracellular substances such as amino acids, purines, pyrimidines and K+. It can also affect the function of nucleoplasm and ribosome. Bacteria are not easily resistant to this product, and there is no cross-resistance with other antibiotics, but there is complete cross-resistance between polymyxin) and B.
Colistin Sulfate premix is light brown or brown granules or powder, easily soluble in water, heat resistant, not easily absorbed by the digestive tract, rapid excretion, low toxicity, no side effects, not easy to produce resistant strains, is one of the safest livestock and poultry growth promotion antibiotics.
Colistin Sulfate is an antibiotic drug used to treat intestinal diseases caused by gram-negative bacilli and has some growth-promoting effects.
Colistin Sulfate is mainly used for sensitive bacterial infections, such as sepsis, acute enteritis, urinary tract infections, etc.
Colistin Sulfate has extremely strong anti-Gram-negative bacillus ability. Especially, it has specific developmental hindering effect on E. coli, Salmonella and Pseudomonas aeruginosa.
|CAS number||1264-72-8||Product Name||Colistin sulfate|
|Manufacture Date||18th Mar.,2022||Analysis Date||18th Mar., 2022|
|Batch NO.||HNB220318-1||Test sample||1000gram|
|Storage||Store in cool&dry place, in well-closed containers.|
|Shelf life||24 Months when properly stored.|
|Appearance||White to yellowish powder||Conforms|
|Solubility||Soluble in water, slightly soluble in ethanol, almost insoluble in acetone, trichloromethane, or ether.||Conforms|
|Loss on drying||≤3.5%||1.25%|
|Sulfate (Dry basis)||16.0%~18.0%||17.9%|
|Related Substances||Any impurity: ≤4.0%||1.33%|
|Total impurity: ≤5.0%||1.89%|
|Potency (Dry basis)||≥19000IU/mg||19560IU/mg|
|Conclusion||Conform with the Standard|