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Pure Colistin Sulfate Powder Veterinary API Raw Material CAS 1264-72-8

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Colistin sulfate
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 1264-72-8 Mf: C52H100N16O17S
MW: 358.21 Specification: 19560IU/mg
EINECS No.: 215-034-3 Appearance: White To Yellowish Powder
Sample: Available
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Pure Colistin Sulfate Powder API


Veterinary API Colistin Sulfate Powder

Product Description

Veternary API raw material pure Colistin sulfate Powder CAS 1264-72-8

Pure Colistin Sulfate Powder Veterinary API Raw Material CAS 1264-72-8 0

Product name

Colistin sulfate


White to yellowish Powder








Keep in cool dry place.

Pure Colistin Sulfate Powder Veterinary API Raw Material CAS 1264-72-8 1


The Introductction of Colistin sulfate


Colistin Sulfate is white or almost white powder, odorless, bitter with moisture-attracting property, easily soluble in water, slightly soluble in methanol, ethanol, almost insoluble in acetone, ether, etc. The free base is slightly soluble in water. It is stable in the range of PH3-7.5.

Colistin Sulfate is produced by Bacillus polymyxa and has a strong antibacterial effect on Gram-negative bacteria and is used to treat intestinal diseases caused by Gram-negative bacteria. It is better in combination with sulfadiazine effect.

Colistin Sulfate is a narrow-spectrum antibiotic. It mainly has strong antibacterial effect on Gram-negative bacteria, and the sensitive bacteria are Pseudomonas aeruginosa, Escherichia coli, Enterobacter spp, Klebsiella spp, Salmonella spp, Shigella spp, Pasteurella spp and Vibrio spp. And Aspergillus spp., Brucella spp., Serratia spp. and all Gram-positive bacteria are resistant to this product. Polymyxins are slow-acting bactericides, mainly acting on bacterial cell membranes. When in contact with sensitive bacteria, the free amino group (positively charged) in their chemical structure binds with the phosphate of phosphate (negatively charged) on bacterial cell membranes, increasing membrane permeability and causing leakage of important intracellular substances such as amino acids, purines, pyrimidines and K+. It can also affect the function of nucleoplasm and ribosome. Bacteria are not easily resistant to this product, and there is no cross-resistance with other antibiotics, but there is complete cross-resistance between polymyxin) and B.

Colistin Sulfate premix is light brown or brown granules or powder, easily soluble in water, heat resistant, not easily absorbed by the digestive tract, rapid excretion, low toxicity, no side effects, not easy to produce resistant strains, is one of the safest livestock and poultry growth promotion antibiotics.


The Application & Function of Colistin sulfate


Colistin Sulfate is an antibiotic drug used to treat intestinal diseases caused by gram-negative bacilli and has some growth-promoting effects.

Colistin Sulfate is mainly used for sensitive bacterial infections, such as sepsis, acute enteritis, urinary tract infections, etc.

Colistin Sulfate has extremely strong anti-Gram-negative bacillus ability. Especially, it has specific developmental hindering effect on E. coli, Salmonella and Pseudomonas aeruginosa.


Other Name of Colistin sulfate:


belcomycin;Animal Feed Additives colistin sulfate Colistin Sulfate; Animal Feed Additives colistin sulfate CAS1264-72-8 ColistinSulfate;liusuanlianjunsu; N-[4-amino-1-[[1-[[4-amino-1-oxo-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino; COLISTINE SULFATE; COLISTIN SULPHATE PURE GRADE; Colistin sulphate premix 10% 40%


The COA of Colistin sulfate


CAS number 1264-72-8 Product Name Colistin sulfate
Manufacture Date 18th Mar.,2022 Analysis Date 18th Mar., 2022
Batch NO. HNB220318-1 Test sample 1000gram
Storage Store in cool&dry place, in well-closed containers.
Shelf life 24 Months when properly stored.


Appearance White to yellowish powder Conforms
  • Take about 20mg of this product, add 2ml of phosphate buffer (pH7.0) and 0.2ml of 0.5%ninhydrin aqueous solution, heat to boil, the solution turns purple.
  • Take about 2mg of this product, add 5ml of water to dissolve it, add 5ml of 10% sodium hydroxide solution, add 5 drops of 1% copper sulfate solution, every 1 drop will be fully shaken, the solution will be reddish purple.
  • Reaction of sulfate salt
Solubility Soluble in water, slightly soluble in ethanol, almost insoluble in acetone, trichloromethane, or ether. Conforms
Loss on drying ≤3.5% 1.25%
PH 4.0~6.0 5.5
Sulfated Ash ≤1.0% 0.04%
Sulfate (Dry basis) 16.0%~18.0% 17.9%
Related Substances Any impurity: ≤4.0% 1.33%
Total impurity: ≤5.0% 1.89%
Potency (Dry basis) ≥19000IU/mg 19560IU/mg
Conclusion Conform with the Standard

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