98% Veterinary API Raw Material Florfenicol Powder CAS 73231-34-2

Veternary API raw material 98% Florfenicol Powder CAS 73231-34-2

The Introductction of Florfenicol

Florfenicol is a synthetic monofluorine derivative of methylsulfonamycin with the molecular formula C12H14Cl2FNO4S. It is a white or off-white crystalline powder, odorless, very slightly soluble in water and chloroform, slightly soluble in glacial acetic acid, and soluble in methanol and ethanol. It is a new broad-spectrum antimicrobial agent of chloramfenicol class for veterinary use, which was successfully developed in the late 1980s.

Florfenicol is an antibiotic drug, which produces broad-spectrum antibacterial effect by inhibiting the activity of peptidyl transferase, and has a wide antibacterial spectrum, including various Gram-positive and negative bacteria and mycoplasma. Sensitive bacteria include Haemophilus, Shigella, Salmonella, E. coli, Pneumococcus, H. influenzae, Streptococcus, Staphylococcus aureus, Chlamydia, Leptospira, Rickettsia, etc. in cattle and pigs. The product can enter the bacterial cell through lipid solubility, and mainly acts on the 50s subunit of the 70s ribosome of bacteria, inhibiting the transpeptidase, blocking the growth of peptidase, inhibiting the formation of peptide chain, thus preventing the synthesis of protein and achieving antibacterial purpose.

Florfenicol is rapidly absorbed orally, widely distributed, with long half-life, high blood concentration and long blood maintenance time.

The Application & Function of Florfenicol

Florfenicol was initially used mainly in aquaculture for the treatment of pseudonuclear pasteurellosis and streptococcal disease in yellowtail and natural outbreaks of boils in Atlantic salmon with remarkable effectiveness.

The main application scope and effects are as follows.

1, livestock: used to prevent and control asthma, infectious pleuropneumonia, atrophic rhinitis, swine pneumonia, streptococcal disease, etc. caused by respiratory distress, elevated body temperature, coughing, choking, reduced food intake, wasting, etc. It is effective for piglets caused by E. coli, etc. yellow and white dysentery, enteritis, hemorrhagic dysentery, edema disease, etc.
2, Poultry: It is used to prevent and treat cholera, white diarrhea, diarrhea, stubborn diarrhea, yellow, white and green stool, watery stool, dysentery, dotted or diffuse bleeding of intestinal mucosa, umbilicus, heart and liver wrapping, chronic respiratory disease caused by bacteria and mycoplasma, infectious rhinitis, cloudy air sac, cough, tracheal croup, respiratory difficulty, etc.
3, It is effective for infectious plasma membrane inflammation, Escherichia coli and Pseudomonas aeruginosa of ducks.
4, Treat bacterial fish disease, internal use.

Other Name of Florfenicol:

2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide
Florfeniol
Flofenicol
2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide

The COA of Florfenicol