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98% Veterinary API Raw Material Florfenicol Powder CAS 73231-34-2

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Florfenicol
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 73231-34-2 Mf: C12H14Cl2FNO4S
MW: 358.21 Specification: 98%
EINECS No.: 642-986-0 Appearance: White Crystalline Powder
Sample: Available
High Light:

API Florfenicol Powder

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CAS 73231-34-2 Veterinary Florfenicol Powder

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98% Veterinary API


Product Description

Veternary API raw material 98% Florfenicol Powder CAS 73231-34-2

98% Veterinary API Raw Material Florfenicol Powder CAS 73231-34-2 0

Product name

Florfenicol

Appearance

White Crystalline Powder

CAS

73231-34-2

MF

C12H14Cl2FNO4S

Purity

99%

Storage

Keep in cool dry place.

98% Veterinary API Raw Material Florfenicol Powder CAS 73231-34-2 1

 

The Introductction of Florfenicol

 

Florfenicol is a synthetic monofluorine derivative of methylsulfonamycin with the molecular formula C12H14Cl2FNO4S. It is a white or off-white crystalline powder, odorless, very slightly soluble in water and chloroform, slightly soluble in glacial acetic acid, and soluble in methanol and ethanol. It is a new broad-spectrum antimicrobial agent of chloramphenicol class for veterinary use, which was successfully developed in the late 1980s.

 

Florfenicol is an antibiotic drug, which produces broad-spectrum antibacterial effect by inhibiting the activity of peptidyl transferase, and has a wide antibacterial spectrum, including various Gram-positive and negative bacteria and mycoplasma. Sensitive bacteria include Haemophilus, Shigella, Salmonella, E. coli, Pneumococcus, H. influenzae, Streptococcus, Staphylococcus aureus, Chlamydia, Leptospira, Rickettsia, etc. in cattle and pigs. The product can enter the bacterial cell through lipid solubility, and mainly acts on the 50s subunit of the 70s ribosome of bacteria, inhibiting the transpeptidase, blocking the growth of peptidase, inhibiting the formation of peptide chain, thus preventing the synthesis of protein and achieving antibacterial purpose.

 

Florfenicol is rapidly absorbed orally, widely distributed, with long half-life, high blood concentration and long blood maintenance time.

 

The Application & Function of Florfenicol

 

Florfenicol was initially used mainly in aquaculture for the treatment of pseudonuclear pasteurellosis and streptococcal disease in yellowtail and natural outbreaks of boils in Atlantic salmon with remarkable effectiveness.

 

The main application scope and effects are as follows.


1, livestock: used to prevent and control asthma, infectious pleuropneumonia, atrophic rhinitis, swine pneumonia, streptococcal disease, etc. caused by respiratory distress, elevated body temperature, coughing, choking, reduced food intake, wasting, etc. It is effective for piglets caused by E. coli, etc. yellow and white dysentery, enteritis, hemorrhagic dysentery, edema disease, etc.
2, Poultry: It is used to prevent and treat cholera, white diarrhea, diarrhea, stubborn diarrhea, yellow, white and green stool, watery stool, dysentery, dotted or diffuse bleeding of intestinal mucosa, umbilicus, heart and liver wrapping, chronic respiratory disease caused by bacteria and mycoplasma, infectious rhinitis, cloudy air sac, cough, tracheal croup, respiratory difficulty, etc.
3, It is effective for infectious plasma membrane inflammation, Escherichia coli and Pseudomonas aeruginosa of ducks.
4, Treat bacterial fish disease, internal use.

 

Other Name of Florfenicol:

 

2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide
Florfeniol
Flofenicol
2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

 

 

The COA of Florfenicol

 

Batch No.: HNB220210
Product Name: Florfenicol
CAS No.: 73231-34-2
Quantity: 1100kg
Man. Date: Feb., 10th, 2022        Analysis Date:Feb., 10th, 2022      Expiry Date: Feb., 11th, 2024
Storage: Store in cool&dry place, in well-closed containers.
Shelf life: 36 Months when properly stored.
Standard: CP2015
ITEMS OF ANALYSIS SPECIFICATIONS RESULT
Solubility Easy soluble in dimethylformamide, soluble in methanol, slight soluble in glacial acetic acid, very slight soluble in water and chloroform. Complies
Characteristics White or almost white crystalline powder Complies
Identification The retention time of the main peak of the sample and the retention time of the main peak of the reference sample should be the same Complies
The infrared absorption spectrum should be consistent with that of the reference sample Complies
Melting point 152℃~156℃ 154.9℃
Specific rotation -16°~-19° -17.1°
Water ≤ 0.5% 1.2%
Related substance Single impurity: ≤ 0.5% 0.32%
Total impurities: ≤ 2% 0.62%
Heavy metals ≤ 20ppm Complies
Chloride ≤ 0.02% <0.02%
Fluorine ≥ 4.8% 4.9%
pH 4.5-6.5 5.9
Residue on Ignition ≤ 0.1% 0.04%
Assay(dry) ≥ 98.0% 98.8%
Conclusion Complies with the CP2015 standard

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