| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Ciprofloxacin Hydrochloride |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually3-5days |
| Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram，Alibaba Assurance Order |
| Supply Ability: | 5000kg/Month |
| CAS: | 93107-08-5 | Mf: | C17H19ClFN3O3.HCl |
|---|---|---|---|
| MW: | 397.83 | Specification: | 99% |
| EINECS No.: | 642-985-5 | Appearance: | White Crystalline Powder |
| Sample: | Available | ||
| High Light: | Ciprofloxacin Hydrochloride Powder Antibiotics,CAS 93107-08-5 API Pharmaceutical,Pharmaceutical Grade Ciprofloxacin Hydrochloride Powder |
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Pharmaceutical Grade Antibiotics 99% Ciprofloxacin Hydrochloride Powder CAS 93107-08-5
|
Product name |
Ciprofloxacin Hydrochloride |
|
Appearance |
White Crystalline Powder |
|
CAS |
93107-08-5 |
|
MF |
C17H19ClFN3O3.HCl |
|
Purity |
99% |
|
Storage |
Keep in cool dry place. |
The Introductction of Ciprofloxacin Hydrochloride
Ciprofloxacin hydrochloride is the hydrochloride salt of ciprofloxacin, which is a synthetic second-generation quinolone antibacterial drug with broad-spectrum antibacterial activity and good bactericidal effect. It is 2-4 times stronger than norfloxacin and enrofloxacin in antibacterial activity against almost all bacteria, and has antibacterial effects on Enterobacter, Pseudomonas aeruginosa, Haemophilus influenzae, gonococcus, streptococcus, Legionella and Staphylococcus aureus.
Ciprofloxacin hydrochloride is white or slightly yellow crystalline powder; almost odorless, bitter taste.
Ciprofloxacin hydrochloride is soluble in water, slightly soluble in methanol, very slightly soluble in ethanol, almost insoluble in chloroform, easily soluble in sodium hydroxide test solution.
The mechanism of action of ciprofloxacin hydrochloride is that it can bind to bacterial DNA gyrase subunit A, which inhibits the cleavage and linkage function of the enzyme and prevents the replication of bacterial DAN, and presents antibacterial effect. It has good water solubility, broad spectrum and high efficiency. It has significant antibacterial effect on Escherichia coli, Salmonella, Pseudomonas aeruginosa, Haemophilus influenzae, gonococcus, streptococcus, Legionella, Staphylococcus aureus, Bacteroides fragilis and Mycoplasma, which is better than other similar drugs as well as cephalosporins and aminoglycosides, and also has obvious effect on β-lactam-resistant and gentamicin-resistant pathogens.
The Application & Ciprofloxacin Hydrochloride
Ciprofloxacin hydrochloride can be used for
(1) genitourinary system infections caused by sensitive bacteria, including simple and complicated urinary tract infections, bacterial prostatitis, Neisseria gonorrhoeae urethritis or cervicitis (including those caused by enzyme-producing strains).
(2) Respiratory tract infections, including acute attacks of bronchial infections and pulmonary infections due to sensitive gram-negative bacilli.
(3) Gastrointestinal infections, caused by Shigella spp., Salmonella spp., enterotoxin-producing Escherichia coli, Aeromonas hydrophila, and Vibrio parahaemolyticus.
(4) Typhoid fever.
(5) Bone and joint infections.
(6) Skin and soft tissue infections.
(7) Septicemia and other systemic infections.
Other Name of Ciprofloxacin Hydrochloride:
(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacidmonohydrochloride;LEVOFLOXACINHYDROCHLORIDE;7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid,9-fluoro-2,3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-,hydrochloride(1:1),(3S)-;3S)-9-Fluoro-2,3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-Chemicalbook7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacidMonohydrochlori;(S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylicacidhydrochloride;-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylicacidhydrochloride;-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl);usp2799%LevofloxacinwhitepowderAntibacterial
The COA of Ciprofloxacin Hydrochloride
Product Name: Ciprofloxacin hydrochloride
Batch Number: HNB220508
| Batch Quantity: 1000kg |
|
Manufacture Date: May.08,2022 Analysis Date: May.09,2022 Expiry Date: May.07,2024 |
| Storage: Store in cool & dry place. Store in well-closed containers. |
| Shelf life: 24 Months when properly stored. |
| ITEMS OF ANALYSIS | SPECIFICATIONS | RESULT |
| Appearance | White or faintly yellowish crystalline powder | Complies |
| Assay by HPLC(dry base) | 98% to 102% | 100.4% |
| Identification | Correspond to retention time of major peak in the chromatogram obtained from the reference solution | Complies |
| IR | Complies | |
| Gives reaction of chlorides | Complies | |
| pH | 3~4.5 | 3.7 |
| Water | 4.7%~6.7% | 5.5% |
| Residue on ignltion | ≤0.1% | 0.0% |
| Iron | ≤0.005% | Not Detected |
| Heavy metals | ≤0.001% | Complies |
| Related Substances | Fluoroquinolonic acid: ≤0.2% | <0.05% |
| Ciprofloxacin ethlenediamine analog: ≤0.2% | <0.05% | |
| Impurities | Any other individual impurities: ≤0.2% | 0.1% |
| Total impurities:≤0.5% | 0.1% | |
| Conclusion | Complied with the USP41 standard | |
